Exposure-response function dataset IEHIAS

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The text on this page is taken from an equivalent page of the IEHIAS-project.

As part of the EU-funded INTARESE project, which contributed to the development of this Toolbox, guidelines were devised for summarising exposure-response functions (ERFs). These guidelines were used to derive a set of 'core' ERFs for a range of environmental stressors and health outcomes, mainly targetted at issues covered by the seven case studies in the INTARESE project.

The attached spreadsheet presents the ERFs, and gives supporting information. Summary ERFs are based on studies published in the peer-reviewed international literature. In addition to the overall effect estimate, the 95% confidence intervals are given as a quantitative measure of uncertainty in the ERFs. The measure of uncertainty includes variability within studies and between studies. The spreadheet also also provides the references used in developing the ERFs.

The ERFs in this data set are likely to be useful in other assessments. Care should nevertheless be applied in using them, for their relevance and validity depends on the policy question, study design and local setting. As a minimum, the summary ERFs should be useful as a starting point in the Issue Framing to decide whether a stressor needs to be quantitatively included in the assessment, and at the Design stage in order to provide a basis foir screening and feasibility testing.

File attachments

See also

Integrated Environmental Health Impact Assessment System
IEHIAS is a website developed by two large EU-funded projects Intarese and Heimtsa. The content from the original website was moved to Opasnet.
Topic Pages
Toolkit
Data

Boundaries · Population: age+sex 100m LAU2 Totals Age and gender · ExpoPlatform · Agriculture emissions · Climate · Soil: Degredation · Atlases: Geochemical Urban · SoDa · PVGIS · CORINE 2000 · Biomarkers: AP As BPA BFRs Cd Dioxins DBPs Fluorinated surfactants Pb Organochlorine insecticides OPs Parabens Phthalates PAHs PCBs · Health: Effects Statistics · CARE · IRTAD · Functions: Impact Exposure-response · Monetary values · Morbidity · Mortality: Database

Examples and case studies Defining question: Agriculture Waste Water · Defining stakeholders: Agriculture Waste Water · Engaging stakeholders: Water · Scenarios: Agriculture Crop CAP Crop allocation Energy crop · Scenario examples: Transport Waste SRES-population UVR and Cancer
Models and methods Ind. select · Mindmap · Diagr. tools · Scen. constr. · Focal sum · Land use · Visual. toolbox · SIENA: Simulator Data Description · Mass balance · Matrix · Princ. comp. · ADMS · CAR · CHIMERE · EcoSenseWeb · H2O Quality · EMF loss · Geomorf · UVR models · INDEX · RISK IAQ · CalTOX · PANGEA · dynamiCROP · IndusChemFate · Transport · PBPK Cd · PBTK dioxin · Exp. Response · Impact calc. · Aguila · Protocol elic. · Info value · DST metadata · E & H: Monitoring Frameworks · Integrated monitoring: Concepts Framework Methods Needs
Listings Health impacts of agricultural land use change · Health impacts of regulative policies on use of DBP in consumer products
Guidance System
The concept
Issue framing Formulating scenarios · Scenarios: Prescriptive Descriptive Predictive Probabilistic · Scoping · Building a conceptual model · Causal chain · Other frameworks · Selecting indicators
Design Learning · Accuracy · Complex exposures · Matching exposure and health · Info needs · Vulnerable groups · Values · Variation · Location · Resolution · Zone design · Timeframes · Justice · Screening · Estimation · Elicitation · Delphi · Extrapolation · Transferring results · Temporal extrapolation · Spatial extrapolation · Triangulation · Rapid modelling · Intake fraction · iF reading · Piloting · Example · Piloting data · Protocol development
Execution Causal chain · Contaminant sources · Disaggregation · Contaminant release · Transport and fate · Source attribution · Multimedia models · Exposure · Exposure modelling · Intake fraction · Exposure-to-intake · Internal dose · Exposure-response · Impact analysis · Monetisation · Monetary values · Uncertainty
Appraisal