ARNT

From Opasnet
Jump to: navigation, search


ARNT: (AH Receptor Nuclear Translocator) a protein in cell nucleus which acts as a partner of AH receptor and some other transcription factors. The complex of AHR + ARNT is called heterodimer, because it is a dimer of two different proteins. ARNT is in fact a misnomer, since it was previously thought to translocate AHR from the cytoplasm of the cell to the nucleus, but in fact it only binds AHR after this has entered the nucleus.[1]

References

  1. Tuomisto, Vartiainen, Tuomisto: Dioxin synopsis. Report / National Institute for Health and Welfare, ISSN 1798-0089 ; 14/2011 [1]