ERF of indoor dampness on respiratory health effects

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Question

What is the association between exposure to indoor dampness and mould in homes and respiratory health effects? ←--#: . The question is clear. --Isabell Rumrich 10:27, 4 February 2013 (EET) (type: truth; paradigms: science: defence)

Answer

Exposure-response function

ERF of indoor dampness on respiratory health effects: Difference between revisions(OR per yes/no visible dampness and/or mold or mold odor)

Obs	Disease	Response metric	Subjects	Exposure route	Exposure metric	Exposure unit	ERF parameter	Threshold	ERF	Description
1	Upper respiratory tract symptoms		All	Inhalation	visible dampness and/or mold or mold odor	yes/no	OR	0	1.70	1.70 (1.44-2.00), No. studies: 13
2	Cough		All	Inhalation	visible dampness and/or mold or mold odor	yes/no	OR	0	1.67	1.67 (1.49-1.86), No. studies: 18
3	Cough		Adults	Inhalation	visible dampness and/or mold or mold odor	yes/no	OR	0	1.52	1.52 (1.18-1.96), No. studies: 6
4	Cough		Children	Inhalation	visible dampness and/or mold or mold odor	yes/no	OR	0	1.75	1.75 (1.56-1.96), No. studies: 6
5	Wheeze		All	Inhalation	visible dampness and/or mold or mold odor	yes/no	OR	0	1.50	1.50 (1.38-1.64), No. studies: 22
6	Wheeze		Adults	Inhalation	visible dampness and/or mold or mold odor	yes/no	OR	0	1.39	1.39 (1.04-1.85), No. studies: 5
7	Wheeze		Children	Inhalation	visible dampness and/or mold or mold odor	yes/no	OR	0	1.53	1.53 (1.39-1.68), No. studies: 17
8	Current asthma		All	Inhalation	visible dampness and/or mold or mold odor	yes/no	OR	0	1.56	1.56 (1.30-1.86), No. studies: 10
9	Ever-diagnosed asthma		All	Inhalation	visible dampness and/or mold or mold odor	yes/no	OR	0	1.37	1.37 (1.23-1.53), No. studies: 8
10	Ever-diagnosed asthma		Children	Inhalation	visible dampness and/or mold or mold odor	yes/no	OR	0	1.35	1.35 (1.20-1.51), No. studies: -
11	Asthma development		All	Inhalation	visible dampness and/or mold or mold odor	yes/no	OR	0	1.34	1.34 (0.86-2.10), No. studies: 4
12	Bronchitis		All	Inhalation	visible dampness and/or mold or mold odor	yes/no	OR	0	1.45	1.45 (1.32-1.59), No. studies: -
13	Bronchitis		Children	Inhalation	visible dampness and/or mold or mold odor	yes/no	OR	0	1.38	1.38 (1.28-1.47), No. studies: -
14	Respiratory infections		All	Inhalation	visible dampness and/or mold or mold odor	yes/no	OR	0	1.44	1.44 (1.31-1.59), No. studies: -
15	Respiratory infections		Adults	Inhalation	visible dampness and/or mold or mold odor	yes/no	OR	0	1.49	1.49 (1.14-1.95), No. studies: -
16	Respiratory infections		Children	Inhalation	visible dampness and/or mold or mold odor	yes/no	OR	0	1.48	1.48 (1.33-1.65), No. studies: -
17	Sensitivity to inhaled antigens		Children	Inhalation	visible dampness and/or mold or mold odor	yes/no	OR	0	1.33	1.33 (1.23-1.44), No. studies: -
18	Hay fever		Children	Inhalation	visible dampness and/or mold or mold odor	yes/no	OR	0	1.35	1.35 (1.18-1.53), No. studies: -

Page-specific entries (indices that have exactly one value each for the whole variable; usually mentioned in the title and/or in the scope.):

• Pollutant: visible dampness and/or mold or mold odor
• Threshold: 0
• Exposure metric: yes/no
• Exposure route: Inhalation

----#: . You can leave the columns listed above out of the table, because all rows have the same value. If you do, then you MUST put the respective information to Category:Exposure-response functions. --Jouni 17:38, 23 January 2012 (EET) (type: truth; paradigms: science: comment)

⇤--#: . If possible, "Disease" should be something that has an ICT-10 code (in this case, the information that is in column "Response metric". In contrast, "Response metric" should describe how the disease was measured: number of cases, incidence, prevalence,... --Jouni 17:38, 23 January 2012 (EET) (type: truth; paradigms: science: attack)

⇤--#: . The comment emphasizing some changes is more than a year old and there are no changes or any kind of reactions to it. --Isabell Rumrich 10:29, 4 February 2013 (EET) (type: truth; paradigms: science: attack)

Rationale

Data

Odds ratios for different health effects in homes with vs. without visible dampness and/or mold or mold odor.

Outcome	Subjects	No. studies	Odds ratio central estimate (95 % CI)	Estimated % increase in damp homes
Upper respiratory tract symptoms	All	13	1.70 (1.44–2.00)	52
Cough	All	18	1.67 (1.49–1.86)	50
	Adults	6	1.52 (1.18–1.96)	–
	Children	12	1.75 (1.56–1.96)	–
Wheeze	All	22	1.50 (1.38–1.64)	44
	Adults	5	1.39 (1.04–1.85)	–
	Children	17	1.53 (1.39–1.68)	–
Current asthma	All	10	1.56 (1.30–1.86)	50
Ever-diagnosed asthma	All	8	1.37 (1.23–1.53)	33
	Children		1.35 (1.20–1.51)
Asthma development	All	4	1.34 (0.86–2.10)	30
Bronchitis	All		1.45 (1.32–1.59)
	Children		1.38 (1.28–1.47)
Respiratory infections	All		1.44 (1.31–1.59)
	Adults		1.49 (1.14–1.95)
	Children		1.48 (1.33–1.65)
Sensitivity to inhaled antigens	Children		1.33 (1.23–1.44)
Hay fever	Children		1.35 (1.18–1.53)

Dependencies

----#: . There are no dependencies listed yet, and we cannot come up with some. --Isabell Rumrich 10:44, 4 February 2013 (EET) (type: truth; paradigms: science: comment)

Unit

⇤--#: . Unit is not a part of Rationale, it could be added to the data table. --Isabell Rumrich 10:37, 4 February 2013 (EET) (type: truth; paradigms: science: attack)

OR per yes/no visible dampness and/or mold or mold odor

Calculations

• Generates random samples of possible ORs.
  • Normal distribution assumed, sd estimated from confidence interval using sd = (upper bound - lower bound)/3.92

+ Show code- Hide code library(OpasnetUtils) library(xtable) ERFindoorDampnessOnRespiratoryHealthEffects <- Ovariable("ERFindoorDampnessOnRespiratoryHealthEffects", ddata = "Op_en4716", getddata = FALSE, save = TRUE) cat("Ovariable ERFindoorDampnessOnRespiratoryHealthEffects saved for later use. Page name: Op_en4716, code name: calculations\n") print(xtable(EvalOutput(ERFindoorDampnessOnRespiratoryHealthEffects)@output), type = "html")

←--#: . R-code runs now. --Isabell Rumrich 10:30, 4 February 2013 (EET) (type: truth; paradigms: science: defence)

See also

• heande:Moisture damage
• Assessment of building policies' effect on dampness and asthma in Europe

Keywords

Dampness and mould, ERF, Respiratory Disease, Asthma, Indoor Environment, Allergy

----#: . We added keywords. --Isabell Rumrich 10:41, 4 February 2013 (EET) (type: truth; paradigms: science: comment)

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