ERF of indoor dampness on respiratory health effects: Difference between revisions

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{{variable|moderator=Ulla H-S}}
{{variable|moderator=Ulla H-S}}


== Scope ==
== Question ==


What is the association between exposure to indoor dampness and mould in homes and respiratory health effects?
What is the association between exposure to indoor dampness and mould in homes and respiratory health effects?
== Answer ==
'''Concentration-response function
<t2b index="Disease,Response metric,Subjects,Exposure route,Exposure metric,Exposure unit,ERF parameter,Threshold,Observation" locations="ERF,Description" unit=" [[OR]] per yes/no visible dampness and/or mold or mold odor
">
Respiratory health effect|Upper respiratory tract symptoms|All|Inhalation|yes/no visible dampness and/or mold or mold odor|-|OR|0|1.70|1.70 (1.44-2.00), No. studies: 13
</t2b>
Page-specific entries (indices that have exactly one value each for the whole variable; usually mentioned in the title and/or in the scope.):
* Pollutant: visible dampness and/or mold or mold odor


== Definition ==
== Definition ==

Revision as of 08:43, 19 January 2012



Question

What is the association between exposure to indoor dampness and mould in homes and respiratory health effects?

Answer

Concentration-response function

ERF of indoor dampness on respiratory health effects: Difference between revisions([[OR]] per yes/no visible dampness and/or mold or mold odor)
ObsDiseaseResponse metricSubjectsExposure routeExposure metricExposure unitERF parameterThresholdERFDescription
1Respiratory health effectUpper respiratory tract symptomsAllInhalationyes/no visible dampness and/or mold or mold odor-OR01.701.70 (1.44-2.00), No. studies: 13

Page-specific entries (indices that have exactly one value each for the whole variable; usually mentioned in the title and/or in the scope.):

  • Pollutant: visible dampness and/or mold or mold odor



Definition

Data

Odds ratios for different health effects in homes with vs. without visible dampness and/or mold or mold odor. [1] [2]
Outcome Subjects No. studies Odds ratio central estimate (95 % CI) Estimated % increase in damp homes
Upper respiratory tract symptoms All 13 1.70 (1.44–2.00) 52
Cough All 18 1.67 (1.49–1.86) 50
Adults 6 1.52 (1.18–1.96)
Children 12 1.75 (1.56–1.96)
Wheeze All 22 1.50 (1.38–1.64) 44
Adults 5 1.39 (1.04–1.85)
Children 17 1.53 (1.39–1.68)
Current asthma All 10 1.56 (1.30–1.86) 50
Ever-diagnosed asthma All 8 1.37 (1.23–1.53) 33
Children 1.35 (1.20–1.51)
Asthma development All 4 1.34 (0.86–2.10) 30
Bronchitis All 1.45 (1.32–1.59)
Children 1.38 (1.28–1.47)
Respiratory infections All 1.44 (1.31–1.59)
Adults 1.49 (1.14–1.95)
Children 1.48 (1.33–1.65)
Sensitivity to inhaled antigens Children 1.33 (1.23–1.44)
Hay fever Children 1.35 (1.18–1.53)

Dependencies

Unit

OR per yes/no visible dampness and/or mold or mold odor

Formula

  • Generates random samples of possible ORs.
    • Normal distribution assumed, sd estimated from confidence interval using sd = (upper bound - lower bound)/3.92
n <- 10000
erf <- rnorm(n, 1.56, (1.86-1.30)/3.92)
dim(erf) <- c(n, 1, 1)
dimnames(erf) <- list(obs=1:n, Outcome="Current asthma", "Age"="All")
erf <- as.data.frame(as.table(erf))

Result

{{#opasnet_base_link:Op_en4716}}


See also

Keywords

References

  1. W. J. Fisk, Q. Lei-Gomez, M. J. Mendell. Meta-analyses of the associations of respiratory health effects with dampness and mold in homes. Indoor Air 2007; 17: 284–296. doi:10.1111/j.1600-0668.2007.00475.x
  2. Mendell et al. 2011. Respiratory and allergic health effects of dampness and mold, and dampness-related agents: a review of the epidemiological evidence. Environmental Health Perspectives 119(6), 748-756.

Related files

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