ERF of waterborne microbes
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Question
What are the dose-response functions of pathogens in drinking water?
Answer
Rationale
Data
| Pathogen | Reference |
| Campylobacter | [1] |
| Rotavirus | [2] |
| Norovirus | [3] |
| Cryptosporidium | [4] |
| Giardia | [5] |
| E.coli O157:H7 | [6] |
| Obs | Pathogen | Function type | Function | Rname | Unit | Param1 | Param2 |
|---|---|---|---|---|---|---|---|
| 1 | Campylobacter | Beta Poisson approximation | 1-(1+Dose/Param2)^-Param1 | f.beta.poisson.approx | No unit | 0.024 | 0.011 |
| 2 | Rotavirus | Exact beta Poisson | 1-exp(-(Param1/(Param1+Param2))*Dose) | f.exact.beta.poisson | No unit | 0.167 | 0.191 |
| 3 | Norovirus | Exact beta Poisson | 1-exp(-(Param1/(Param1+Param2))*Dose) | f.exact.beta.poisson | No unit | 0.04 | 0.055 |
| 4 | Cryptosporidium | Exact beta Poisson | 1-exp(-(Param1/(Param1+Param2))*Dose) | f.exact.beta.poisson | No unit | 0.115 | 0.176 |
| 5 | Giardia | Exponential | 1-exp(-Param1*Dose) | f.exponential | No unit | 0.0199 | 0 |
| 6 | E.coli O157:H7 | Exact beta Poisson | 1-exp(-(Param1/(Param1+Param2))*Dose) | f.exact.beta.poisson | No unit | 0.157 | 9.16 |
Calculations
See also
References
- ↑ Campylobacter (Teunis et al. 2005) Exact Beta-Poisson model Low Dose Approximation:Dose Response relationship for Campylobacter from model fit results presented by Teunis et al. (2005) Epidemiol. Infec. 133, 583-592.
- ↑ Teunis, P. F. M. and Havelaar, A. (2000). "The beta Poisson dose‐response model is not a single hit model."Risk Analysis 20(4): 511‐518.
- ↑ Teunis et al. 2008 Norwalk Virus: How Infectious is It? Journal of Medical Virology 80:1468-1476.
- ↑ Teunis et al., 2002 Risk Analysis 22(1) 175-183
- ↑ Teunis et al., 1996 RIVM report No. 284550002 " The dose-response relation in human volunteers for gastro-intestinal pathogens"
- ↑ Teunis, P., Takumi, K. and Shinagawa, K. (2004). "Dose response for infection by Escherichia coli O157:H7 from outbreak data." Risk Analysis 24(2): 401‐407.
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