User:Jouni
Jouni Tuomisto
academy researcher
National Public Health Institute (KTL)
P.O.Box 95
FI-70701 Kuopio
Finland
Personal information
Jouni T. Tuomisto
- Researcher 1992-2005, KTL
- Post-doc researcher 2000-2001, Harvard School of Public Health
- Academy researcher 2005-2010, Academy of Finland and KTL
- Senior researcher and chief researcher 2010-, THL
- National Institute for Health and Welfare (THL)
- Department of Health Protection
- P.O.Box 95, FI-70701 Kuopio
email: firstname.lastname@thl.fi
phone: +358295246305
Areas of interest
- Open policy practice
- Open assessment
- Improved methods for risk analysis
- Decision analysis
- Fine particles
- Dioxins and other persistent pollutants
- Energy production and its emissions
- Climate change
I have medical background (Lic. Med. 1992 and Dr. Med. Sci. 1999 from the University of Kuopio). I started my research career with dioxin toxicology and did mechanistic research in rats on several areas: inheritance of dioxin resistance; feeding behaviour, body weight regulation and related neurotransmitter changes in hypothalamus; dose-response studies and modelling on various endpoints; tumour promotion; a particular liver syndrome resulting in biliverdin accumulation. At the same time, I coordinated a large case-control study on dioxins and soft-tissue sarcoma, where the patients were collected from 16 hospitals in Southern Finland. After my thesis (1999) I went to Harvard Center for Risk Analysis (Harvard University, Boston, USA) as a post-doc (2000-2001). I studied risk analysis, probability theory, and decision analysis, and did research on health risks of fine particles. I learned new methods, such as elicitation of expert judgement that is used when estimates are needed for risk assessment but measurements are not possible. I also used probabilistic methods such as Monte Carlo simulation and developed risk models for fine particles. During my stay in Boston, KTL/Environmental Health (YTOS) applied for the status of Centre of Excellence for Environmental Health Risk Analysis. The application was based on the excellent research performed in the fields of environmental epidemiology, exposure assessment, and toxicology in YTOS on dioxins and air pollution. This existing knowledge base was complemented by methods I learnt in Harvard. The application was successful, and YTOS had the status of the Centre of Excellence during 2002-2007. I have been the group leader of the risk analysis group in the Centre since the beginning. I have performed or supervised research on the health effects of fine particles from buses in Helsinki Metropolitan Area; risks and benefits of eating farmed salmon; comparative risks on cancer and developmental defects due to dioxin in food; health effects of the total fine particle emissions in Finland; and health effects of different traffic scenarios. I coordinated the EU research application Beneris, which was about developing risk assessment methodologies for risks in food. There were seven partners from different countries in Europe, and it was a major effort in and resource for food risk assessment in Finland, as KTL has a major role in the application. I was a workpackage leader in a large integrated project INTARESE about environmental health risks (funded by the EU for 2005-2010). The topic of the workpackage is risk characterisation. A special focus is on tools, methods, and computer programs for assessing and characterising risks. I have participated in research projects about fine particles and energy production (BIOHER, CLAIH) coordinated by THL. I have supervised the health impact assessment part of the projects. In addition, I am a workpackage leader in the project URGENCHE that broadens the scope from fine particles to other health impacts of climate change mitigation. My major scientific contribution is nowadays the development of open assessment. Is is an assessment method or framework that improves traditional decision analyses or impact assessments by opening up the process of making the assessment to collaboration between experts, decision makers, and stakeholders without hampering scientific scrutiny. I have also developed a web workspace Opasnet for making such assessments online. Several research projects are actively using the website for their research and assessments.
Education
- Med. Lic. 1992
- Dr. Med. Sci. 1999
- Adjunct professor (docent) (field: toxicology, especially risk assessment) 2004
Current research
Selected publications
- Tuomisto JT, Tainio M: An economic way of reducing health, environmental, and other pressures of urban traffic: a decision analysis on trip aggregation. BMC Public Health 2005, 5:123. http://www.biomedcentral.com/1471-2458/5/123/abstract
- Tuomisto, JT; Wilson, A; Cooke, RM; Tainio, M; Evans, JS. 2005. Mortality in Kuwait due to pm from oil fires after the Gulf War: Combining expert elicitation assessments. EPIDEMIOLOGY 16 (5): S74-S75.
- Tuomisto, JT; Pekkanen, J. 2005. Assessing environmental health risks or net health benefits?. SCANDINAVIAN JOURNAL OF PUBLIC HEALTH 33 (3): 162-163.
- Tuomisto, JT; Tuomisto, J; Tainio, M; Niittynen, M; Verkasalo, P; Vartiainen, T; Kiviranta, H; Pekkanen, J. 2004. Risk-benefit analysis of eating farmed salmon. SCIENCE 305 (5683): 476-476.
- Tuomisto, JT; Pekkanen, J; Kiviranta, H; Tukiainen, E; Vartiainen, T; Tuomisto, J. 2004. Soft-tissue sarcoma and dioxin: A case-control study. INTERNATIONAL JOURNAL OF CANCER 108 (6): 893-900.
- Niittynen, M; Tuomisto, JT; Auriola, S; Pohjanvirta, R; Syrjala, P; Simanainen, U; Viluksela, M; Tuomisto, J. 2003. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced accumulation of biliverdin and hepatic peliosis in rats.. TOXICOLOGICAL SCIENCES 72 (1): 361-362, Suppl. S.
- Levy, JI; Carrothers, TJ; Tuomisto, JT; Hammitt, JK; Evans, JS. 2001. Assessing the public health benefits of reduced ozone concentrations. ENVIRONMENTAL HEALTH PERSPECTIVES 109 (12): 1215-1226.
- Tuomisto, JT; Viluksela, M; Pohjanvirta, R; Tuomisto, J. 1999. The AH receptor and a novel gene determine acute toxic responses to TCDD: Segregation of the resistant alleles to different rat lines. TOXICOLOGY AND APPLIED PHARMACOLOGY 155 (1): 71-81.
List of publications
Jouni T. Tuomisto (1967): Scientific publications 22 January 2014
A. Peer-reviewed scientific articles
- 1991
- Tuomisto JT, Unkila M, Pohjanvirta R, Koulu M, Tuomisto L. Effect of A Single Dose of Tcdd on the Level of Histamine in Discrete Nuclei in Rat-Brain. Agents Actions 1991; 33(1-2):154-156.
- 1993
- Pohjanvirta R, Unkila M, Tuomisto JT, Vuolteenaho O, Leppaluoto J, Tuomisto J. Effect of 2,3,7,8-Tetrachlorodibenzo-P-Dioxin (Tcdd) on Plasma and Tissue Beta-Endorphin-Like Immunoreactivity in the Most Tcdd-Susceptible and the Most Tcdd-Resistant Rat Strain. Life Sci 1993; 53(19):1479-1487.
- Unkila M, Tuomisto JT, Pohjanvirta R, MacDonald E, Tuomisto L, Koulu M et al. Effect of A Single Lethal Dose of Tcdd on the Levels of Monoamines, Their Metabolites and Tryptophan in Discrete Brain Nuclei and Peripheral-Tissues of Long-Evans Rats. Pharmacol Toxicol 1993; 72(4-5):279-285.
- Pohjanvirta R, Unkila M, Tuomisto JT, Tuomisto J. TCDD reduces selectively plasma ß-endorphin levels in TCDD-susceptible Long-Evans rats but not in TCDD-resistant Han/Wistar rats. Organohalogen Comp 1993; 13:297-300.
- Tuomisto JT, Pohjanvirta R, Unkila M, Räisänen L, Tuomisto J. Effects of TCDD on motor activity of TCDD-susceptible and -resistant rat strains. Organohalogen Comp 1993; 13:313-315.
- 1994
- Unkila M, Pohjanvirta R, MacDonald E, Tuomisto JT, Tuomisto J. Dose-Response and Time-Course of Alterations in Tryptophan-Metabolism by 2,3,7,8-Tetrachlorodibenzo-P-Dioxin (Tcdd) in the Most Tcdd-Susceptible and the Most Tcdd-Resistant Rat Strain - Relationship with Tcdd Lethality. Toxicol Appl Pharmacol 1994; 128(2):280-292.
- Pohjanvirta R, Unkila M, Tuomisto JT, Tuomisto J. Modulation of TCDD-induced wasting syndrome by diabetes. Organohalogen Comp 1994; 21:315-318.
- 1995
- Pohjanvirta R, Unkila M, Linden J, Tuomisto JT, Tuomisto J. Toxic Equivalency Factors do Not Predict the Acute Toxicities of Dioxins in Rats. Eur J Pharmacol Env Toxicol Pharmacol 1995; 293(4):341-353.
- Tuomisto JT, Pohjanvirta R, Unkila M, Tuomisto J. 2,3,7,8-Tetrachlorodibenzo-P-Dioxin-Induced Anorexia and Wasting Syndrome in Rats - Aggravation After Ventromedial Hypothalamic-Lesion. Eur J Pharmacol Env Toxicol Pharmacol 1995; 293(4):309-317.
- Unkila M, Ruotsalainen M, Pohjanvirta R, Viluksela M, MacDonald E, Tuomisto JT et al. Effect of 2,3,7,8-Tetrachlorodibenzo-P-Dioxin (Tcdd) on Tryptophan and Glucose-Homeostasis in the Most Tcdd-Susceptible and the Most Tcdd-Resistant Species, Guinea-Pigs and Hamsters. Arch Toxicol 1995; 69(10):677-683.
- Unkila M, Pohjanvirta R, Tuomisto JT, Tuomisto J. Alterations in Plasma Tryptophan Binding to Albumin in 2,3,7,8-Tetrachlorodibenzo-P-Dioxin-Treated Long-Evans Rats. Eur J Pharmacol Env Toxicol Pharmacol 1995; 293(2):115-121.
- Vartiainen T, Lampi P, Tuomisto JT, Tuomisto J. Polychlorodibenzo-P-Dioxin and Polychlorodibenzofuran Concentrations in Human Fat Samples in A Village After Pollution of Drinking-Water with Chlorophenols. Chemosphere 1995; 30(8):1429-1438.
- Unkila M, Pohjanvirta R, Viluksela M, Tuomisto JT, Rozman K, Tuomisto J. Effect of TCDD on tryptophan and glucose homeostasis in the most TCDD-susceptible and the most TCDD-resistant species guinea pigs and hamsters. Organohalogen Comp 1995; 25:219-223.
- Unkila M, Pohjanvirta R, Viluksela M, Tuomisto JT, Rozman K, Tuomisto J. Effect of TCDD on tryptophan and glucose homeostasis in the most TCDD-susceptible and the most TCDD-resistant species, guinea pigs and hamsters. Organohalogen Comp 1995; 25:219-223.
- 1996
- Tuomisto JT, Pohjanvirta R, Unkila M, Viluksela M, Tuomisto J. TCDD blocks the weight increasing effect of paraventricular lesion. Organohalogen Comp 1996; 29:371-374.
- Unkila M, Pohjanvirta R, Tuomisto JT, Viluksela M, Tuomisto J. Amelioration of short-term toxicity of TCDD with a fish oil rich in omega-3 fatty acids in Long-Evans rats. Organohalogen Comp 1996; 29:277-280.
- Viluksela M, Pohjanvirta R, Tuomisto JT, Unkila M, Tuomisto J. Nitric oxide antagonist N-nitro-L-arginine decreases the lethality of TCDD in mice, but increases it in rats. Organohalogen Comp 1996; 29:272-276.
- 1998
- Valjakka A, Vartiainen J, Tuomisto L, Tuomisto JT, Olkkonen H, Airaksinen MM. The fasciculus retroflexus controls the integrity of REM sleep by supporting the generation of hippocampal theta rhythm and rapid eye movements in rats. Brain Res Bull 1998; 47(2):171-184.
- Pohjanvirta R, Simanainen U, Viluksela M, Tuomisto JT, Tuomisto J. Effect of geldanamycin on the acute toxicity of TCDD. Organohalogen Comp 1998; 37:191-194.
- Tuomisto JT, Pohjanvirta R, Viluksela M, Tuomisto J. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and lesion of dorsomedial hypothalamic nucleus have additive effects on body weight loss. Organohalogen Comp 1998; 37:81-83.
- Viluksela M, Simanainen U, Tuomisto JT, Pohjanvirta R, Harper PA, Okey AB et al. Characterization of the deviant structure-activity relationship for chlorinated dibenzo-p-dioxins (CDDs) in the resistant Han/Wistar rats. Organohalogen Comp 1998; 38:287-290.
- Pekkanen J, Tuomisto JT. Väestönkasvu on vain yksi taudeista. Duodecim 1998; 114:594.
- 1999
- Pohjanvirta R, Viluksela M, Tuomisto JT, Unkila M, Karasinska J, Franc MA et al. Physicochemical differences in the AH receptors of the most TCDD-susceptible and the most TCDD-resistant rat strains. Toxicol Appl Pharmacol 1999; 155(1):82-95.
- Tuomisto JT, Viluksela M, Pohjanvirta R, Tuomisto J. The AH receptor and a novel gene determine acute toxic responses to TCDD: Segregation of the resistant alleles to different rat lines. Toxicol Appl Pharmacol 1999; 155(1):71-81.
- Tuomisto JT, Pohjanvirta R, Unkila M, Tuomisto J. TCDD-induced anorexia and wasting syndrome in rats: Effects of diet-induced obesity and nutrition. Pharmacology Biochemistry and Behavior 1999; 62(4):735-742.
- Viluksela M, Unkila M, Pohjanvirta R, Tuomisto JT, Stahl BU, Rozman KK et al. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on liver phosphoenolpyruvate carboxykinase (PEPCK) activity, glucose homeostasis and plasma amino acid concentrations in the most TCDD-susceptible and the most TCDD-resistant rat strains. Arch Toxicol 1999; 73(6):323-336.
- Strandman T, Koistinen J, Kiviranta H, Vuorinen PJ, Tuomisto JT, Tuomisto J et al. Levels of some polybrominated diphenyl ethers (PBDEs) in fish and human adipose tissue in Finland. Organohalogen Comp 1999; 40:355-358.
- 2000
- Kiviranta H, Vartiainen T, Verta M, Tuomisto JT, Tuomisto J. High fish-specific dioxin concentrations in Finland. Lancet 2000; 355(9218):1883-1885.
- Tuomisto JT, Viluksela M, Pohjanvirta R, Tuomisto J. Changes in food intake and food selection in rats after 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure. Pharmacology Biochemistry and Behavior 2000; 65(3):381-387.
- Viluksela M, Bager Y, Tuomisto JT, Scheu G, Unkila M, Pohjanvirta R et al. Liver tumor-promoting activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in TCDD-sensitive and TCDD-resistant rat strains. Cancer Res 2000; 60(24):6911-6920.
- Kattainen H, Simanainen U, Tuomisto JT, Kovero O, Alaluusua S, Tuomisto J et al. In utero/lactational TCDD exposure impairs the molar tooth development in rats. Organohalogen Comp 2000; 49:229-232.
- Simanainen U, Tuomisto JT, Kattainen H, Tuomisto J, Viluksela M. Effects of in utero and lactational TCDD exposure on male reproduction pattern in three differentially TCDD sensitive rat lines. Organohalogen Comp 2000; 49:342-344.
- Tuomisto JT, Pekkanen J, Kiviranta H, Tukiainen E, Vartiainen T, Tuomisto J. Soft tissue sarcoma and dioxin exposure in Finnish general population. Organohalogen Comp 2000; 48:107-110.
- 2001
- Jämsä T, Viluksela M, Tuomisto JT, Tuomisto J, Tuukkanen J. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on bone in two rat strains with different aryl hydrocarbon receptor structures. J Bone Miner Res 2001; 16(10):1812-1820.
- Kattainen H, Tuukkanen J, Simanainen U, Tuomisto JT, Kovero O, Lukinmaa PL et al. In utero/lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure impairs molar tooth development in rats. Toxicol Appl Pharmacol 2001; 174(3):216-224.
- Levy JI, Carrothers TJ, Tuomisto JT, Hammitt JK, Evans JS. Assessing the public health benefits of reduced ozone concentrations. Environ Health Perspect 2001; 109(12):1215-1226.
- 2002
- Kiukkonen A, Viluksela M, Sahlberg C, Alaluusua S, Tuomisto JT, Tuomisto J et al. Response of the incisor tooth to 2,3,7,8-tetrachlorodibenzo-p-dioxin in a dioxin-resistant and a dioxin-sensitive rat strain. Toxicol Sci 2002; 69(2):482-489.
- Niittynen M, Tuomisto JT, Auriola S, Pohjanvirta R, Syrjala P, Simanainen U et al. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-induced accumulation of biliverdin and hepatic peliosis in rats. Toxicol Sci 2002; 71(1):112-123.
- Pohjanvirta R, Korkalainen M, McGuire J, Simanainen U, Juvonen R, Tuomisto JT et al. Comparison of acute toxicities of indolo[3,2-b]carbazole (ICZ) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in TCDD-sensitive rats. Food Chem Toxicol 2002; 40(7):1023-1032.
- Simanainen U, Tuomisto JT, Tuomisto J, Viluksela M. Structure-activity relationships and dose responses of polychlorinated dibenzo-p-dioxins for short-term effects in 2,3,7,8-tetrachlorodibenzo-p-dioxin-resistant and -sensitive rat strains. Toxicol Appl Pharmacol 2002; 181(1):38-47.
- Fletcher N, Stern N, Viluksela M, Tuomisto JT, Pohjanvirta R, Tuomisto J et al. The retinoid response in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-treated Long-Evans and Han/Wistar rats. Organohalogen Comp 2002; 55:437-439.
- 2003
- Simanainen U, Tuomisto JT, Tuomisto J, Viluksela M. Dose-response analysis of short-term effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in three differentially susceptible rat lines. Toxicol Appl Pharmacol 2003; 187(2):128-136.
- Stern N, Lind PM, Larsson S, Viluksela M, Tuomisto JT, Tuomisto J et al. TCDD induces trabecular bone loss and bone fragility in a TCDD-sensitive but not in a TCDD-resistant rat strain. Organohalogen Comp 2003; 64:312-315.
- 2004
- Miettinen HM, Huuskonen H, Partanen AM, Miettinen P, Tuomisto JT, Pohjanvirta R et al. Effects of epidermal growth factor receptor deficiency and 2,3,7,8-tetrachlor.odibenzo-p-dioxin on fetal development in mice. Toxicology Letters 2004; 150(3):285-291.
- Simanainen U, Adamsson A, Tuomisto JT, Miettinen HM, Toppari J, Tuomisto J et al. Adult 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure and effects on male reproductive organs in three differentially TCDD-susceptible rat lines. Toxicol Sci 2004; 81(2):401-407.
- Simanainen U, Haavisto T, Tuomisto JT, Paranko J, Toppari J, Tuomisto J et al. Pattern of male reproductive system effects after in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure in three differentially TCDD-sensitive rat lines. Toxicol Sci 2004; 80(1):101-108.
- Simanainen U, Tuomisto JT, Pohjanvirta R, Syrjala P, Tuomisto J, Viluksela M. Postnatal development of resistance to short-term high-dose toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in TCDD-resistant and -semiresistant rats. Toxicol Appl Pharmacol 2004; 196(1):11-19.
- Tuomisto J, Pekkanen J, Kiviranta H, Tukiainen E, Vartiainen T, Viluksela M et al. Dioxin cancer risk - example of hormesis? Non linearity in Biology, Toxicology and Medicine 2004.
- Tuomisto JT, Pekkanen J, Kiviranta H, Tukiainen E, Vartiainen T, Tuomisto J. Soft-tissue sarcoma and dioxin: A case-control study. Int J Cancer 2004; 108(6):893-900.
- Tuomisto JT, Tuomisto J, Tainio M, Niittynen M, Verkasalo P, Vartiainen T et al. Risk-benefit analysis of eating farmed salmon. Science 2004; 305(5683):476.
- 2005
- Tuomisto, JT; Pekkanen, J. 2005. Assessing environmental health risks or net health benefits?. SCANDINAVIAN JOURNAL OF PUBLIC HEALTH 33 (3): 162-163.
- Tuomisto, JT; Tainio, M. 2005. An economic way of reducing health, environmental, and other pressures of urban traffic: a decision analysis on trip aggregation. BMC PUBLIC HEALTH 5:123.
- Kiviranta, H; Tuomisto, JT; Tuomisto, J; Tukiainen, E; Vartiainen, T. 2005. Polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls in the general population in Finland. CHEMOSPHERE 60 (7): 854-869.
- Fletcher, N; Giese, N; Schmidt, C; Stern, N; Lind, PM; Viluksela, M; Tuomisto, JT; Tuomisto, J; Nau, H; Hakansson, H. 2005. Altered retinoid metabolism in female long-evans and Han/Wistar rats following long-term 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-treatment. TOXICOLOGICAL SCIENCES 86 (2): 264-272.
- Hanninen, OO; Palonen, J; Tuomisto, JT; Yli-Tuomi, T; Seppanen, O; Jantunen, MJ. 2005. Reduction potential of urban PM2.5 mortality risk using modern ventilation systems in buildings. INDOOR AIR 15 (4): 246-256.
- Hanninen, OO; Tuomisto, JT; Jantunen, MJ. 2005. Characterization of model error in a simulation of fine particulate matter exposure distributions of the working age population in Helsinki, Finland. JOURNAL OF THE AIR & WASTE MANAGEMENT ASSOCIATION 55 (4): 446-457.
- Tainio, M; Tuomisto, JT; Hanninen, O; Aarnio, P; Koistinen, KJ; Jantunen, MJ; Pekkanen, J. 2005. Health effects caused by primary fine particulate matter (PM2.5) emitted from buses in the Helsinki metropolitan area, Finland. RISK ANALYSIS 25 (1): 151-160.
- 2006
- Tuomisto J, Pekkanen J, Kiviranta H, Tukiainen E, Vartiainen T, Viluksela M, Tuomisto JT. Dioxin Cancer Risk - Example of Hormesis? Dose Response. 2006 May 1;3(3):332-341. [1]
- 2007
- van Bree, L; Fudge, N; Tuomisto, JT; Brunekreef, B. 2007. Closing the gap between science and policy on air pollution and health. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES 70 (3-4): 377-381.
- Tainio M, Tuomisto JT, Hanninen O, et al.: Parameter and model uncertainty in a life-table model for fine particles (PM2.5): a statistical modeling study. ENVIRONMENTAL HEALTH, 6 (Article 6) AUG 23 2007.
- Cooke RM, Wilson AM, Tuomisto JT, et al. A Probabilistic characterization of the relationship between fine particulate matter and mortality: Elicitation of European experts. ENVIRONMENTAL SCIENCE & TECHNOLOGY 41 (18): 6598-6605 SEP 15 2007. [2]
- Niittynen M, Simanainen U, Syrjala P, et al. Differences in acute toxicity syndromes of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 1,2,3,4,7,8-hexachlorodibenzo-p-dioxin in rats. TOXICOLOGY 235 (1-2): 39-51 JUN 3 2007 2007.
- Kiljunen M, Vanhatalo M, Mantyniemi S, et al. Human dietary intake of organochlorines from Baltic herring: Implications of individual fish variability and fisheries management. AMBIO 36 (2-3): 257-264 APR 2007.
- Main KM, Kiviranta H, Virtanen HE, Sundqvist E, Tuomisto JT, Tuomisto J, Vartiainen T, Skakkebaek NE, Toppari J. Flame retardants in placenta and breast milk and cryptorchidism in newborn boys. Environ Health Perspect. 2007 Oct;115(10):1519-26. [3]
- 2008
- Jouni T. Tuomisto, Andrew Wilson, John S. Evans, Marko Tainio. 2008. Uncertainty in mortality response to airborne fine particulate matter: Combining European air pollution experts. Reliability Engineering and System Safety 93: 732-744. doi:10.1016/j.ress.2007.03.002
- Niittynen M, Tuomisto JT, Pohjanvirta R. Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on heme oxygenase-1, biliverdin IXalpha reductase and delta-aminolevulinic acid synthetase 1 in rats with wild-type or variant AH receptor. Toxicology. 2008 Sep 4;250(2-3):132-42. Epub 2008 Jul 10. [4]
- Karvosenoja, N (Karvosenoja, Niko); Tainio, M (Tainio, Marko); Kupiainen, K (Kupiainen, Kaarle); Tuomisto, JT (Tuomisto, Jouni T.); Kukkonen, J (Kukkonen, Jaakko); Johansson, M (Johansson, Matti). Evaluation of the emissions and uncertainties of PM2.5 originated from vehicular traffic and domestic wood combustion in Finland. BOREAL ENVIRONMENT RESEARCH, 13 (5): 465-474 OCT 31 2008.
- Leino O, Tainio M, Tuomisto JT. Comparative risk analysis of dioxins in fish and fine particles from heavy-duty vehicles. Risk Anal. 2008 Feb;28(1):127-40. [5]
- Franc MA, Moffat ID, Boutros PC, Tuomisto JT, Tuomisto J, Pohjanvirta R, Okey AB. Patterns of dioxin-altered mRNA expression in livers of dioxin-sensitive versus dioxin-resistant rats. Arch Toxicol. 2008 Nov;82(11):809-30. Epub 2008 May 9. Erratum in: Arch Toxicol. 2008 Nov;82(11):831. [6]
- 2009
- Marko Tainio, Mikhail Sofiev, Mika Hujo, Jouni T. Tuomisto, Miranda Loh, Matti J. Jantunen, Ari Karppinen, Leena Kangas, Niko Karvosenoja, Kaarle Kupiainen, Petri Porvari, Jaakko Kukkonen: Evaluation of the European population intake fractions for European and Finnish anthropogenic primary fine particulate matter emissions. Atmospheric Environment 43 (2009) 3052–3059.
- Marko Tainio, Niko Karvosenoja, Petri Porvari, Arjen Raateland, Jouni T. Tuomisto, Matti Johansson, Jaakko Kukkonen, Kaarle Kupiainen: A simple concept for GIS-based estimation of population exposure to primary fine particles from vehicular traffic and domestic wood combustion. Boreal Environment Research 14 (2009): 850-860.
- 2010
- Sand S, Fletcher N, von Rosen D, Kalantari F, Viluksela M, Tuomisto JT, Tuomisto J, Falk-Filipsson A, Håkansson H. Quantitative and statistical analysis of differences in sensitivity between Long-Evans and Han/Wistar rats following long-term exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Regul Toxicol Pharmacol. 2010 Jul-Aug;57(2-3):136-45. Epub 2010 Feb 4. [7]
- Herlin M, Kalantari F, Stern N, Sand S, Larsson S, Viluksela M, Tuomisto JT, Tuomisto J, Tuukkanen J, Jämsä T, Lind PM, Håkansson H. Quantitative characterization of changes in bone geometry, mineral density and biomechanical properties in two rat strains with different Ah-receptor structures after long-term exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicology. 2010 Jun 29;273(1-3):1-11. Epub 2010 Apr 18. [8]
- Hirvonen T, Sinkko H, Hallikainen A, Kiviranta H, Pietinen P, Valsta L, Tuomisto JT. Modelling the intake of polychlorinated dibenzo-p-dioxins and dibenzofurans: impact of energy under-reporting and number of reporting days in dietary surveys. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2010 Aug;27(8):1170-6. [9]
- Tainio, M (Tainio, M.); Tuomisto, JT (Tuomisto, J. T.); Pekkanen, J (Pekkanen, J.); Karvosenoja, N (Karvosenoja, N.); Kupiainen, K (Kupiainen, K.); Porvari, P (Porvari, P.); Sofiev, M (Sofiev, M.); Karppinen, A (Karppinen, A.); Kangas, L (Kangas, L.); Kukkonen, J (Kukkonen, J.): Uncertainty in health risks due to anthropogenic primary fine particulate matter from different source types in Finland. ATMOSPHERIC ENVIRONMENT 2010: 44 (17): 2125-2132 doi:10.1016/j.atmosenv.2010.02.036
- 2011
- Lensu S, Tuomisto JT, Tuomisto J, Pohjanvirta R. Characterization of the 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-provoked strong and rapid aversion to unfamiliar foodstuffs in rats. Toxicology. 2011 May 10;283(2-3):140-50. Epub 2011 Mar 22. [10]
- Lensu S, Tuomisto JT, Tuomisto J, Viluksela M, Niittynen M, Pohjanvirta R. Immediate and highly sensitive aversion response to a novel food item linked to AH receptor stimulation. Toxicol Lett. 2011 Jun 24;203(3):252-7. Epub 2011 Mar 31. [11]
- Pohjola MV, Tuomisto JT. Openness in participation, assessment, and policy making upon issues of environment and environmental health: a review of literature and recent project results. Environ Health. 2011 Jun 16;10:58. [12]
- Pohjola, M.V., Pohjola, P., Paavola, S., Bauters, M., Tuomisto, J.T., 2011b. Pragmatic knowledge services. Journal of Universal Computer Science 17, 472-497. doi:10.3217/jucs-017-03-0472
- 2012
- H. E. Virtanen, J. J. Koskenniemi, E. Sundqvist, K. M. Main, H. Kiviranta, J. T. Tuomisto, J. Tuomisto, M. Viluksela, T. Vartiainen, N. E. Skakkebaek and J. Toppari. Associations between congenital cryptorchidism in newborn boys and levels of dioxins and PCBs in placenta. Int J Androl. 2012 Jun;35(3):283-93. doi: 10.1111/j.1365-2605.2011.01233.x. Epub 2011 Dec 13. doi:10.1111/j.1365-2605.2011.01233.x ISSN 0105-6263
- Verhagen H, Tijhuis MJ, Gunnlaugsdottir H, Kalogeras N, Leino O, Luteijn JM, Magnússon SH, Odekerken G, Pohjola MV, Tuomisto JT, Ueland O, White BC, Holm F. State of the art in benefit-risk analysis: Introduction. Food Chem Toxicol. (2012) 50: 1: 2-4. [13]
- Tijhuis MJ, de Jong N, Pohjola MV, Gunnlaugsdóttir H, Hendriksen M, Hoekstra J, Holm F, Kalogeras N, Leino O, van Leeuwen FX, Luteijn JM, Magnússon SH, Odekerken G, Rompelberg C, Tuomisto JT, Ueland O, White BC, Verhagen H. State of the art in benefit-risk analysis: Food and nutrition. Food Chem Toxicol. (2012) 50: 1: 5-25. [14]
- Luteijn JM, White BC, Gunnlaugsdóttir H, Holm F, Kalogeras N, Leino O, Magnússon SH, Odekerken G, Pohjola MV, Tijhuis MJ, Tuomisto JT, Ueland O, McCarron PA, Verhagen H. State of the art in benefit-risk analysis: Medicines. Food Chem Toxicol. (2012) 50: 1: 26-32 [15]
- Magnússon SH, Gunnlaugsdóttir H, van Loveren H, Holm F, Kalogeras N, Leino O, Luteijn JM, Odekerken G, Pohjola MV, Tijhuis MJ, Tuomisto JT, Ueland O, White BC, Verhagen H. State of the art in benefit-risk analysis: Food microbiology. Food Chem Toxicol. (2012) 50: 1: 33-39. [16]
- Pohjola MV, Leino O, Kollanus V, Tuomisto JT, Gunnlaugsdóttir H, Holm F, Kalogeras N, Luteijn JM, Magnússon SH, Odekerken G, Tijhuis MJ, Ueland O, White BC, Verhagen H. State of the art in benefit-risk analysis: Environmental health. Food Chem Toxicol. (2012) 50: 1: 40-55. [17]
- Kalogeras N, Odekerken-Schröder G, Pennings JM, Gunnlaugsdottir H, Holm F, Leino O, Luteijn JM, Magnússon SH, Pohjola MV, Tijhuis MJ, Tuomisto JT, Ueland O, White BC, Verhagen H. State of the art in benefit-risk analysis: Economics and Marketing-Finance. Food Chem Toxicol. (2012) 50: 1: 56-66. [18]
- Ueland O, Gunnlaugsdottir H, Holm F, Kalogeras N, Leino O, Luteijn JM, Magnússon SH, Odekerken G, Pohjola MV, Tijhuis MJ, Tuomisto JT, White BC, Verhagen H. State of the art in benefit-risk analysis: Consumer perception. Food Chem Toxicol. (2012) 50: 1: 67-76. [19]
- Tijhuis, M.J., Pohjola, M.V., Gunnlaugsdóttir, H., Kalogeras, N., Leino, O., Luteijn, J.M., Magnússon, S.H., Odekerken, G., Poto, M., Tuomisto, J.T., Ueland, Ø., White, B.C., Holm, F., Verhagen, H., 2011. Looking beyond Borders: Integrating best practices in benefit-risk analysis into the field of food and nutrition. Food and Chemical Toxicology (2012) 50: 1: 77-93. doi:10.1016/j.fct.2011.11.044
- Karjalainen AK, Hirvonen T, Kiviranta H, Sinkko H, Kronberg-Kippilä C, Virtanen SM, Hallikainen A, Leino O, Knip M, Veijola R, Simell O, Tuomisto JT. Long-term daily intake estimates of polychlorinated dibenzo-p-dioxins and furans, polychlorinated biphenyls and polybrominated diphenylethers from food in Finnish children: risk assessment implications. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2012;29(9):1475-88. doi:10.1080/19440049.2012.694373 . [20].
- Tuomisto J, Tuomisto JT. Is the fear of dioxin cancer more harmful than dioxin? Toxicol Lett. 2012 May 5;210(3):338-44. doi:10.1016/j.toxlet.2012.02.007 . [21].
- Virtanen HE, Koskenniemi JJ, Sundqvist E, Main KM, Kiviranta H, Tuomisto JT, Tuomisto J, Viluksela M, Vartiainen T, Skakkebaek NE, Toppari J. Associations between congenital cryptorchidism in newborn boys and levels of dioxins and PCBs in placenta. Int J Androl. 2012 Jun;35(3):283-93. doi:10.1111/j.1365-2605.2011.01233.x . [22].
- 2013
- Anna K. Karjalainen, Anja Hallikainen, Tero Hirvonen, Hannu Kiviranta, Mikael Knip, Carina Kronberg-Kippilä, Olli Leino, Olli Simell, Harri Sinkko, Jouni T. Tuomisto, Riitta Veijola, Eija-Riitta Venäläinen, Suvi M. Virtanen. Estimated intake levels for Finnish children of methylmercury from fish. Food and Chemical Toxicology: Volume 54, April 2013, Pages 70-77. doi:10.1016/j.fct.2012.02.074 [23].
- Leino O, Kiviranta H, Karjalainen AK, Kronberg-Kippilä C, Sinkko H, Larsen EH, Virtanen S, Tuomisto JT. Pollutant concentrations in placenta. Food Chem Toxicol. 2013 Apr;54:59-69. doi:10.1016/j.fct.2011.10.058 . [24].
- Mikko V. Pohjola, Pasi Pohjola, Marko Tainio, Jouni T. Tuomisto: Perspectives to Performance of Environment and Health Assessments and Models—From Outputs to Outcomes? (Review). Int. J. Environ. Res. Public Health 2013, 10, 2621-2642; doi:10.3390/ijerph10072621
- Leino O, Karjalainen AK, Tuomisto JT. Effects of docosahexaenoic acid and methylmercury on child's brain development due to consumption of fish by Finnish mother during pregnancy: A probabilistic modeling approach. Food Chem Toxicol. 2013 Apr;54:50-8. doi: 10.1016/j.fct.2011.06.052. Epub 2011 Jun 23. [Epub ahead of print] [25] doi:10.1016/j.fct.2011.06.052
- 2014
- Niittynen M, Simanainen U, Pohjanvirta R, Sankari S, Tuomisto JT. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Increases Bilirubin Formation but Hampers Quantitative Hepatic Conversion of Biliverdin to Bilirubin in Rats with Wild-Type AH Receptor. Basic Clin Pharmacol Toxicol. 2014 Jan 13. doi: 10.1111/bcpt.12191. [Epub ahead of print]
- Sandström, Vilma; Tuomisto, Jouni T.; Majaniemi, Sami; Rintala, Teemu; Pohjola, Mikko V.: Evaluating effectiveness of open assessments on alternative biofuel sources. Sustainability: Science, Practice & Policy (2014): 10(1) Published online May 16, 2014. [26]
- Fantke, P., Jolliet, O., Apte, J.S., Cohen, A.J., Evans, J.S., Hänninen, O.O., Hurley, F., Jantunen, M.J., Jerrett, M., Levy, J.I., Loh, M.M., Marshall, J.D., Miller, B.G., Preiss, P., Spadaro, J.V., Tainio, M., Tuomisto, J.T., Weschler, C.J., McKone, T.E., 2014. Health effects of fine particulate matter in life cycle impact assessment: Conclusions from the Basel guidance workshop. The International Journal of Life Cycle Assessment, doi:10.1007/s11367-11014-10822-11362
B. Non-refereed scientific articles
- Tuomisto JT, Unkila M, Pohjanvirta R, MacDonald E, Tuomisto L. Effect of a single dose of TCDD on the level of histamine in discrete nuclei in rat brain. XIX Meeting of the European Histamine Research Society. Abstracts. Kuopio: University of Kuopio, 1990: 117.
- Unkila M, Tuomisto JT, Pohjanvirta R, MacDonald E, Tuomisto L, Tuomisto J. Effect of a single dose of TCDD on the levels of monoamines, their metabolites and tryptophan in discrete hypothalamic nuclei of rat brain. Acta Univ Tamperensis ser B 1990; 33:67.
- Tuomisto J, Tuomisto JT, Unkila M, Pohjanvirta R. TCDD completely reverses the hyperphagia due to VMH lesion. Soc Neurosci Abstr , 1993.
- Tuomisto JT, Pohjanvirta R, Unkila M, Tuomisto J. TCDD reduces feed intake of rats despite hyperphagia by VMH lesion. In: Tuomisto J, Ruuskanen J, editors. Proceedings of the First Finnish Conference of Environmental Sciences. Kuopio: University of Kuopio, 1993: 369-371.
- Tuomisto JT, Pohjanvirta R, Unkila M, Tuomisto J. TCDD reduces feed intake of rats despite hyperphagia by VMH lesion. Pharmacol Toxicol 1993; 73, suppl.II:115.
- Pohjanvirta R, Laitinen J, Unkila M, Tuomisto JT, Tuomisto J. TCDD may induce an alternative metabolic route for melatonin in the rat. Hum Exp Toxicol 1994; 13:807.
- Tuomisto JT, Pohjanvirta R, Unkila M, Tuomisto J. Effects of TCDD on spontaneous motor activity of rats and guinea pigs. Hum Exp Toxicol 1994; 13:808.
- Unkila M, Pohjanvirta R, Tuomisto JT, Tuomisto J. Characterization of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced changes in plasma tryptophan binding to albumin. Hum Exp Toxicol 1994; 13:808.
- Tuomisto JT, Pohjanvirta R, Unkila M, Tuomisto J. Effects of nutrition and forced feeding on 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) -induced wasting syndrome in rats. In: Saski E, Saarinen T, editors. Helsinki: University of Helsinki, 1995: 153-156.
- Tuomisto JT. Environmental and other attitudes among Finnish scouts and non-scouts. In: Saski E, Saarinen T, editors. Helsinki: University of Helsinki, 1995: 71-72.
- Tuomisto JT, Pohjanvirta R, Unkila M, Tuomisto J. Interactions between TCDD and weight increasing factors. Toxicologist 1995; 15:67.
- Unkila M, Pohjanvirta R, Tuomisto JT, Tuomisto J. TCDD-induced changes in tryptophan (TRP) in rats: Association with TCDD lethality. Toxicologist 1995; 15:67.
- Tuomisto JT, Unkila M, Pohjanvirta R, Viluksela M, Tuomisto J. TCDD cancels the effects on body weight of lesions of ventromedical hypothalamic and paraventricular nuclei. Proc Neurosci Abstr 1996; 22, part 2:1409.
- Unkila M, Marjakangas O, Viluksela M, Pohjanvirta R, Tuomisto JT, Tuomisto J. Tumor necrosis factor a (TNF-a) does not play a major role in the acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the rat. Joint Meeting of the Finnish Society of Toxicology and the British Toxicology Society 1996.
- Tuomisto JT, Pohjanvirta R, Viluksela M, Tuomisto J. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and lesion of hypothalamic dorsomedial nucleus have additive effects on body weight loss. In: Högmander H, Oikari A, editors. Proceedings of the Third Finnish Conference of Environmental Sciences. Jyväskylä: University of Jyväskylä, 1997: 291-293.
- Tuomisto JT, Laaksonen M, Viluksela M, Pohjanvirta R, Tuomisto J. Minor changes in leptin levels after 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure. Pharmacol Toxicol 1997; 80, Suppl. III:113.
- Tuomisto JT, Pohjanvirta R, Viluksela M, Tuomisto J. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and lesion of hypothalamic dorsomedial nucleus have additive effects on body weight loss. Finnish-Estonian Congress of Toxicology, Tartu, May 22-24 1997;67.
- Viluksela M, Bager Y, Tuomisto JT, Unkila M, Pohjanvirta R, Flodström S et al. Comparison of liver tumor promoting activity of TCDD in a TCDD-sensitive and a TCDD-resistant rat strain. Pharmacol Toxicol 1997; 80, Suppl. III:152.
- Pohjanvirta R, Juvonen R, Tuomisto JT, Unkila M, Viluksela M, Bergman J et al. Indolol(3,2-b)carbazole (ICZ) is a weaker Ah receptor agonist in vivo than in vitro. Toxicol Lett 1998; suppl. 1/95:102.
- Tuomisto JT, Viluksela M, Tuomisto J. Separation of Ah receptor and another dioxin resistance gene in new rat lines. Toxicol Sci 1998; 42:66.
- Viluksela M, Unkila M, Stahl BU, Pohjanvirta R, Tuomisto JT, Rozman KK et al. Effects of TCDD on the liver phosphoenolpyruvate carboxykinase (PEPCK) activity and glucose homeostasis in a TCDD-susceptible and a TCDD-resistant rat strain. Toxicol Sci 1998; 42:381.
- Tuomisto JT, Alm S, Juuti S, Kettunen A, Kurttio P, Pekkanen J et al. Pyrkilo method in a complicated environmental health problem: Paakkila asbestos mine case, Finland. In: Kuusisto S, Isoaho S, Puhakka J, editors. Proceedings. Fourth Finnish Conference of Environmental Sciences. Tampere: Tampere University of Technology, 1999: 244-247.
- Tuomisto JT, Pekkanen J, Alm S, Kurttio P, Venalainen R, Juuti S et al. Deliberation process by an explicit factor-effect-value network (Pyrkilo): Paakkila asbestos mine case, Finland. Epidemiol 1999; 10(4):S114.
- Jämsä T, Viluksela M, Tuomisto JT, Tuomisto J, Tuukkanen J. Peripheral quantitative computed tomography and three-point bending test in evaluating the effect of dioxins on rat long bones. Proceedings of the 12th Conference of the European Society of Biomechanics. Dublin: 2000: 339.
- Tuomisto JT, Celebi C, Simanainen U, Haavisto AM, Skakkebaek NE, Tuomisto J et al. Testicular toxicity of TCDD in a TCDD-sensitive and a TCDD-resistant rat strain: a stereological analysis. Toxicol Sci 2000; 54, suppl:276.
- Viluksela M, Bager Y, Tuomisto JT, Scheu G, Unkila M, Pohjanvirta R et al. Liver tumor promoting activity of TCDD in a TCDD-sensitive and a TCDD-resistant rat strain. Toxicol Sci 2000; 54, suppl:276.
- Kattainen H, Tuukkanen J, Simanainen U, Tuomisto JT, Kovero O, Alaluusua S et al. Impairment of molar tooth development after low dose in utero/lactational TCDD exposure in rats. Pharmacol Toxicol 2001; 88, suppl. I:20.
- Kattainen H, Tuukkanen J, Simanainen U, Tuomisto JT, Kovero O, Lukinmaa P-L et al. Toxicological significance of dioxin-induced defects in tooth development. Kuopio University Publications D 2001; 249:57.
- Kiukkonen AP, Viluksela M, Alaluusua S, Sahlberg C, Tuomisto JT, Tuomisto J. Response of H/W and L-E rat incisors to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Int Assoc Dentl Res Congress . 2001.
- Pohjanvirta R, Korkalainen M, McQuire J, Simanainen U, Juvonen R, Tuomisto JT et al. Toxicity of indolo(3,2-b)carbazole (ICZ) in vivo. Kuopio University Publications D 2001; 249:64.
- Tuomisto JT. Centre of Environmental Health Risk Analysis: Working between science and policy. Airnet . 2002.
- Tuomisto JT, Pekkanen J, Kiviranta H, Tukiainen E, Vartiainen T, Tuomisto J. Soft tissue sarcoma and dioxins - A case-control study. Epidemiol 2002; 13(4):S187.
- Tuomisto JT, Simanainen U, Viluksela M, Pohjanvirta R, Tuomisto J. Postnatal development of resistance to acute lethality of TCDD in two TCDD-resistant rat strains. Toxicol Sci 2002; 66:334.
- Viluksela M, Jämsä T, Kattainen H, Simanainen U, Tuomisto JT, Tuomisto J et al. Effects of in utero/lactational exposure to TCDD on bone in rats. Toxicol Sci 2002; 66:170.
- Fletcher N, Schmidt C, Stern N, Viluksela M, Tuomisto JT, Pohjanvirta R et al. Hepatic retinoid levels in a TCDD-sensitive (Long-Evans) and TCDD-resistant (Han/Wistar) rat strain following long-term low-dose TCDD exposure. Toxicol Sci 2003; 72(S-1):1763.
- Niittynen M, Tuomisto JT, Auriola S, Pohjanvirta R, Syrjala P, Simanainen U et al. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced accumulation of biliverdin and hepatic peliosis in rats. Toxicol Sci 2003; 72(S-1):1756.
- Simanainen U, Niittynen M, Tuomisto JT, Pohjanvirta R, Viluksela M, Tuomisto J. Differences in acute toxicity syndromes of TCDD and hexachlorodibenzo-p-dioxin in rats. Toxicol Sci 2003; 72(S-1):1753.
- Tainio M, Tuomisto JT. Comparing methodologies of six fine particle risk assessments. In: Honkanen J, Koponen P, editors. Proceedings. Sixth Finnish Conference of Environmental Sciences. Joensuu: University of Joensuu, 2003.
- Tainio M, Tuomisto JT, Aarnio P, Jantunen M, Koistinen K, Hänninen O et al. Estimation of the contributions of different sources to average PM2.5 exposure of the adult population of Helsinki. 13th Annual Conference of International Society of Exposure Analysis. Abstract book. Stresa, Italy: International Society of Exposure Analysis, 2003.
- Tainio M, Tuomisto JT, Aarnio P, Jantunen M, Pekkanen J. Comparison of different bus types and mortality due to fine particulate matter in Helsinki, Finland. World Congress on Risk.Abstracts , 44. 2003.
- Giese N, Fletcher N, Schmidt C, Stern N, Viluksela M, Tuomisto JT et al. Altered retinoid metabolism in rat strains with different sensitivity to TCDD toxicity. Toxicol Appl Pharmacol 2004; 197(3):212.
- Hänninen O, Tuomisto JT, Yli-Tuomi T, Jantunen M. Reduction of urban population mortality risk caused by PM2.5 using modern ventilation systems in buildings. 2004.
- Niittynen M, Tuomisto JT, Tuomisto J, Korkalainen M, Pohjanvirta R. The effect of TCDD on mRNA expression of key heme metabolic enzymes in rats with hepatic biliverdin accumulation. Toxicol Appl Pharmacol 2004; 197(3):215.
- Pohjanvirta R, Unkila M, Tuomisto JT, Viluksela M, Okey AB, Tuomisto J. Rat strain difference-based animal model for mechanistic studies of dioxin toxicity. Toxicology 2004; 194(3):221.
- Simanainen U, Miettinen HM, Haavisto T, Adamsson A, Koistinen J, Tuomisto JT et al. Comparison of sensitivity to male reproductive system effects after fetal and adult tetrachlorodibenzo-P-dioxin (TCDD) exposure. Toxicol Appl Pharmacol 2004; 197(3):354.
- Tuomisto JT, Tainio M, Pekkanen J, Tuomisto J. Comparative risk analysis of dioxins and fine particulate matter. Toxicol Appl Pharmacol 2004; 197(3):169.
- Viluksela M, Saurola P, Koivusaari J, Finnlund M, Verta M, Erasto P et al. Time trends of persistent halogenated aromatic hydrocarbons in Osprey (Pandion haliaetus) eggs in Finland. Toxicol Appl Pharmacol 2004; 197(3):216.
- Tuomisto, JT; Tainio, M; Pekkanen, J; Tuomisto, J. 2004. Comparative risk analysis of dioxins and fine particulate matter. TOXICOLOGY AND APPLIED PHARMACOLOGY 197 (3): 169-169.
- Giese, N; Fletcher, N; Schmidt, C; Stern, N; Viluksela, M; Tuomisto, JT; Tuomisto, J; Hakansson, H; Nau, H. 2004. Altered retinoid metabolism in rat strains with different sensitivity to TCDD toxicity. TOXICOLOGY AND APPLIED PHARMACOLOGY 197 (3): 212-212.
- Niittynen, M; Tuomisto, JT; Tuomisto, J; Korkalainen, M; Pohjanvirta, R. 2004. The effect of TCDD on mRNA expression of key heme metabolic enzymes in rats with hepatic biliverdin accumulation. TOXICOLOGY AND APPLIED PHARMACOLOGY 197 (3): 215-215.
- Viluksela, M; Saurola, P; Koivusaari, J; Finnlund, M; Verta, M; Erasto, P; Tuomisto, JT; Kiviranta, H. 2004. Time trends of persistent halogenated aromatic hydrocarbons in Osprey (Pandion haliaetus) eggs in Finland. TOXICOLOGY AND APPLIED PHARMACOLOGY 197 (3): 216-216.
- Tuomisto, JT; Wilson, A; Cooke, RM; Tainio, M; Evans, JS. 2005. Mortality in Kuwait due to pm from oil fires after the Gulf War: Combining expert elicitation assessments. EPIDEMIOLOGY 16 (5): S74-S75.
- Evans, JS; Wilson, A; Tuomisto, JT; Tainio, M; Cooke, RM. 2005. What risk assessment can tell us about the mortality impacts of the Kuwaiti oil fires. EPIDEMIOLOGY 16 (5): S137-S138.
- Hanninen, O; Tuomisto, JT; Tainio, M; Jantunen, M. 2006. Five approaches to PM2.5 exposure reduction in a northern metropolitan area. EPIDEMIOLOGY 17 (6): S522-S522, Suppl. S.
- Tuomisto, JT; Tainio, M. 2006. Extended causal diagrams in describing environmental health risks. EPIDEMIOLOGY 17 (6): S524-S524, Suppl. S.
- Sand, S; Fletcher, N; von Rosen, D; Victorin, K; Viluksela, M; Tuomisto, JT; Tuomisto, J; Filipsson, AF; Hakansson, H. 2006. Quantitative and statistical analysis of differences in sensitivity between Long-Evans and Han/Wistar rats following long-term exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. TOXICOLOGY LETTERS 164: S74-S74.
- Tuomisto, J; Leino, O; Kiviranta, H; Tuomisto, JT. 2006. Use of intake fraction to improve dioxin risk assessment. TOXICOLOGY LETTERS 164: S148-S149.
- Tuomisto, JT: A saga of industrial pollution. Science 19 July 2013: Vol. 341 no. 6143 pp. 238-239. doi:10.1126/science.1240379 .
- Teemu Rintala, Einari Happonen, Jouni Tuomisto: OpasnetUtils. Utility functions for dealing with data in Opasnet (www.opasnet.org) environment. A software package for R. Version 1.0.0. CRAN, 2013. [28], accessed 19 July 2013.
- Helga Gunnlaugsdottir and Jouni T. Tuomisto. Foreword. Integrated Benefit and Risk Analysis for Assessing Food Safety and Health Benefit; Results from QALIBRA and BENERIS. (Editorial) Food and Chemical Toxicology: Volume 54, April 2013, Pages 1–2. doi:10.1016/j.fct.2011.09.020
- Niittynen M, Pärjälä E, Tuomisto JT. Increased use of biomass in combined heat and power production: health impacts due to PM2.5 emissions. Abstracts of the 2013 Conference of the International Society of Environmental Epidemiology (ISEE), the International Society of Exposure Science (ISES), and the International Society of Indoor Air Quality and Climate (ISIAQ), August 19–23, 2013, Basel, Switzerland. 2013. Environ Health Perspect; http://dx.doi.org/10.1289/ehp.ehbasel13.
- Tuomisto JT, Torras Ortiz S, Niittynen M. Online energy balance tool to assess health impacts of climate policies in cities - case EU (Kuopio, Stuttgart) and China (Suzhou). Abstracts of the 2013 Conference of the International Society of Environmental Epidemiology (ISEE), the International Society of Exposure Science (ISES), and the International Society of Indoor Air Quality and Climate (ISIAQ), August 19–23, 2013, Basel, Switzerland. 2013. Environ Health Perspect; http://dx.doi.org/10.1289/ehp.ehbasel13.
- Jantunen M, Asikainen A, Niittynen M, Pärjälä E, Tuomisto JT. Conceptual model linking urban GHG policies to health and wellbeing (URGENCHE). Abstracts of the 2013 Conference of the International Society of Environmental Epidemiology (ISEE), the International Society of Exposure Science (ISES), and the International Society of Indoor Air Quality and Climate (ISIAQ), August 19–23, 2013, Basel, Switzerland. 2013. Environ Health Perspect; http://dx.doi.org/10.1289/ehp.ehbasel13.
C. Scientific monographs
- Tuomisto J, Vartiainen T, Tuomisto JT. Synopsis on dioxins and PCBs. Kuopio: National Public Health Institute, 1999.
- Tuomisto JT. TCDD: a challenge to mechanistic toxicology [Dissertation]. Kuopio: National Public Health Institute, 1999.
- Tainio M, Tuomisto JT, Aarnio P, Jantunen M, Koistinen K, Hänninen O et al. Eri bussitekniikoiden vaikutus pienhiukkasten aiheuttamaan kuolleisuuteen Pääkaupunkiseudulla vuonna 2020. Monisteita 2004:1. 2004. Helsinki, Ministry of Social Effects and Health. ISBN 952-00-1459-4, ISSN 1237-200X.
- Tuomisto JT, Pohjola M: Open risk assessment. A new way of providing scientific information for decision-making. Publications of the National Public Health Institute B18/2007. 2007
- Tuomisto JT. Foreword. Food Chem Toxicol. 2013 Apr;54:1-2. doi:10.1016/j.fct.2011.09.020 . [27].
- Tuomisto, Jouko; Vartiainen, Terttu; Tuomisto, Jouni T. Synopsis on dioxins and PCBs. National Institute for Health and Welfare, Report 14/2011.
- Hans Verhagen and Olli Leino (Eds.)Integrated Benefit and Risk Analysis for Assessing Food Safety and Health Benefit; Results from QALIBRA and BENERIS. Volume 54, Pages 1-78 (April 2013). (Jouni Tuomisto has written the Foreword and three original articles in this special issue.)
D. Publications intended for professional communities
- Carrothers TJ, Wolff SK, Tuomisto JT, Wilson A, Levy JI, Graham JD et al. Fine particulate air pollution in the US: a preliminary analysis of the value of research. In: European Commission, WHO, European Collaborative Action, editors. Role of human exposure assessment in air quality management. Report on the joint workshop. 2004.
- Tuomisto JT. Concepts of science-policy interface: Concepts in current practice and potential areas of development. In: van Bree L, Fudge N, Tuomisto JT, editors. Airnet Science/Policy Interface report. Utrecht, the Netherlands: 2004.
- Tuomisto JT, Tainio M. Health impact assessment of primary fine particles (PM2.5) emitted from busses in Helsinkin Metropolitan Area, Finland. In: Hurley F, Sanderson E, editors. Airnet Health Impact Assessment report. Utrecht, the Netherlands: 2004.
- Tuomisto JT. Terveydelle haitalliset yhdyskuntailman saasteet ja toksiset aineet. Kirjassa Koulu M, Tuomisto J. Farmakologia & toksikologia (luku 77).
- Ahtoniemi, Pauliina; Tainio, Marko; Tuomisto, Jouni T; Karvosenoja, Niko; Kupiainen, Kaarle; Porvari, Petri; Karppinen, Ari; Kangas, Leena; Kukkonen, Jaakko. Health risks from nearby sources of fine particulate matter : Domestic wood combustion and road traffic (PILTTI) [Pienhiukkasten lähipäästöjen terveysriskit: puun pienpoltto ja tieliikenne (PILTTI)]. National Institute for Health and Welfare, Report 3/2010.
- Kauppila, Tommi; Komulainen, Hannu; Makkonen, Sari; Tuomisto, Jouni T (eds.). 2013. Metallikaivosalueiden ympäristöriskinarviointiosaamisen kehittäminen: MINERA-hankkeen loppuraportti. [Summary: Improving Environmental Risk Assessments for Metal Mines: Final Report of the MINERA Project.] Geology Survey Finland, Research Report 199. 223 pages. ISBN 978-952-217-231-0 (PDF) [28]
- Tuomisto, Jouni. Toms River A Story of Science and Salvation. SCIENCE 2013-08-15.
- Komulainen, Hannu; Kallio, Antti; Tuomisto, Jouni: Kaivostoiminnan ympäristöterveysriskit. Ympäristö ja Terveys-lehti, 2014-12-15, ISSN 0358-3333.
- Asikainen, Arja; Pärjälä, Erkki; Kettunen, Tapio; Niittynen, Marjo; Tuomisto, Jouni. Kasvihuonekaasupäästöjen paikallisten vähentämistoimenpiteiden vaikutukset Kuopiossa. Ympäristö ja terveys-lehti 2014-10-13.
- Hänninen, Otto; Kutvonen, Juho; Rumrich, Isabella; Asikainen, Arja; Tuomisto, Jouni. Tupakka, radon ja ympäristöterveys. Ympäristö ja Terveys-lehti 2014-09-15, ISSN 0358-3333.
- Tuomisto, Jouni T.; Pohjola, Mikko; Pohjola, Pasi. Avoin päätöksentekokäytäntö voisi parantaa tiedon hyödyntämistä. Yhteiskuntapolitiikka 1/2014, 66-75. http://urn.fi/URN:NBN:fi-fe2014031821621
- Tuomisto, Jouni T.; Hänninen, Otto; Asikainen, Arja; Pohjola, Mikko. Ympäristöterveysriskien torjunta osana kestävää kehitystä. Ympäristö ja Terveys-lehti 2014.
⇤--#: . Tästä puuttuvat mm. ilmastonmuutostyöryhmän raportit! --Jouni (talk) 13:32, 28 January 2015 (UTC) (type: truth; paradigms: science: attack)
----#: . Article in trade journal; article in a professional manual or guide of professional information system, textbook material; professional conference proceedings; published development or research report or study; textbook, professional manual or guide, dictionary --Lhiq 16:09, 11 September 2013 (EEST) (type: truth; paradigms: science: comment)
E. Publications intended for the general public, linked to the applicant's research
----#: . Popularised article, newspaper article; popularised monograph (no letters to editor, short commentaries of self-published works) --Lhiq 16:16, 11 September 2013 (EEST) (type: truth; paradigms: science: comment)
F. Public artistic and design activities
----#: . Published independent work of art; public partial realisation of a work of art; public artistic performance or exhibition; model or design adopted for production/use --Lhiq 16:17, 11 September 2013 (EEST) (type: truth; paradigms: science: comment)
G. Theses
- Tuomisto JT. TCDD: a challenge to mechanistic toxicology [Dissertation]. Kuopio: National Public Health Institute, 1999.
----#: . Polytechnic thesis, Bachelor's thesis, Master's thesis, polytechnic Master's thesis; Licenciate thesis; doctoral dissertation (monograph); doctoral dissertation (article) --Lhiq 16:08, 11 September 2013 (EEST) (type: truth; paradigms: science: comment)
H. Patents and invention disclosures
----#: . Granted patent; invention disclousure --Lhiq 16:18, 11 September 2013 (EEST) (type: truth; paradigms: science: comment)
I. Audiovisual material, ICT software
----#: . Audiovisual material, ICT software --Lhiq 16:19, 11 September 2013 (EEST) (type: truth; paradigms: science: comment)
Websites
- Opasnet contributors. (2013). Opasnet. An English web workspace for providing scientific information to help societal decision-making. http://en.opasnet.org (accessed 19 April 2013. Own contribution: 2202 pages edited, contribution score: 2339.)
- Opasnet contributors (2013). Opasnet. A Finnish web workspace for providing scientific information to help societal decision-making. http://fi.opasnet.org (accessed 19 April 2013. Own contribution: 1170 pages edited, contribution score: 1277.)
⇤--#: . En osaa sijoittaa näitä mihinkään --Lhiq 16:15, 11 September 2013 (EEST) (type: truth; paradigms: science: attack)
Links
Key words
References
Files
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