Osteoporosis

This page is a knowledge crystal of subtype variable. The page identifier is Op_en4523
Moderator:Teemu R (see all)
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This page is a part of Heimtsa incidence database.

Scope

What is the prevalence of osteoporosis in the general population?

Definition

Rate (age, sex ratio)	Context (population size studied, location, date data taken, end-point measured)	Definition of end-point	Reference
Spain: ~2 million women with osteoporosis; prevalent in 26.1% of women 50+	Contains information on fractures and prevalence of osteoporosis across Europe with references for each of the facts
7.8 million affected (6.5 million women)	Germany, 2003	Claims data for patients with osteoporosis (M80, M81) or an osteoporosis-related fracture diagnosis (S22, S32, S42, S52, S72, S82) or treatment with anti-osteoporosis drugs
40.8% in women >50 and 17.7% in men >50	Denmark, 1995-1999	Based on normal Danish values for BMD, the expected number of subjects aged 50 years + with osteoporosis according to the WHO definition was calculated
Women, 45-59yrs 5.0% had a BMD <2.5 SD of the mean premenopausal reference value and were thus considered to be osteoporotic. Patients were classified as slow (41.7%), borderline (28.2%), and fast (30.1%) bone losers. By integrating the estimated annual percent bone loss with baseline bone mineral content, 27.6% of the postmenopausal women were identified as at risk of developing osteoporosis at age 65 years.	n=2286, Italy, risk of osteoporosis	Risk of osteoporosis by combining a baseline distal forearm bone mineral content measurement with an estimation of annual percent bone loss as shown by plasma bone Gla protein, serum alkaline phosphatase, and fasting urinary creatinine-corrected calcium and hydroxyproline
Prevalence of osteoporosis at the age intervals shown in Sweden using female-derived reference ranges at the femoral neck. (Reprinted from [24] reference missing) Men Women Age range %of Number %of Number (years) population affected (000) population affected (000) 50–54 2.5 7.0 6.3 17.0 55–59 3.5 7.6 9.6 21.1 60–64 5.8 11.4 14.3 30.0 65–69 7.4 14.2 20.2 43.7 70–74 7.8 14.6 27.9 63.0 75–79 10.3 13.7 37.5 68.3 80–84 16.6 14.7 47.2 67.8 50–80 6.3 83.2 21.2 310.9	Sweden, osteoporosis, paper contains other tables and data	WHO criteria

Result

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