ERF of omega-3 fatty acids

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Scope

What is the exposure-response function (ERF) of omega-3 fatty acids?

Definition

Exposure-response of fish oil intake for MI risk in adults is indexed by variable age. It applies to the last two age categories.

Data

The study by Cohen et al. 2005 ^[1] estimates that increasing maternal docosahexaenoic acid (DHA) intake by 100 mg/day increases child's IQ by 0.13 points D↷. This value represents central estimate while the upper and lower bound for this ERF is 0.08 and 0.18. Triangular distribution is used.

Dependencies

None defined.

Unit

IQ points/(100mg omega-3/d)

Formula

Result

ERF of omega-3 fatty acids(?)
Obs	Trait	Response metric	Exposure route	Exposure metric	Exposure unit	Threshold	ERF parameter	ERF	Description
1	IQ	Change in IQ points	Placenta				ERS	0.07(±0,01)
2	myocardial infarction		fish ingestion

References

↑ Cohen, J.T., PhD, Bellinger, D.C, PhD, W.E., MD, Bennett A., and Shaywitz B.A. 2005b. A Quantitative Analysis of Prenatal Intake of n-3 Polyunsaturated Fatty Acids and Cognitive Development. American Journal of Preventive Medicine 2005;29(4):366–374).

[1] Cohen, J.T., PhD, Bellinger, D.C, PhD, W.E., MD, Bennett A., and Shaywitz B.A. 2005b. A Quantitative Analysis of Prenatal Intake of n-3 Polyunsaturated Fatty Acids and Cognitive Development. American Journal of Preventive Medicine 2005;29(4):366–374).

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