Disability weights: Difference between revisions
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'''Arguments defending this approach include:''' | '''Arguments defending this approach include:''' | ||
- DALY weights are an intrinsically subjective value for which no "true estimate" exists. They should be treated as a normative value, which does not need further uncertainty intervals. | - DALY weights are an intrinsically subjective value for which no "true estimate" exists. They should be treated as a normative value, which does not need further uncertainty intervals. | ||
- Uncertainty in very small DALY weights (for less severe effects) affects overall outcomes of DALY calculations much more than uncertainty in large disability weights. This is a "flaw" of the method: if health would be defined as 1 and death as 0 (as is being done with QALYs), the more severe outcomes would have more overall uncertainty. The uncertainty is greatest for the smallest disability weights and narrows as more severe weights are attained (figure 5.16<ref> Colin D. Mathers, Joshua A. Salomon, Majid Ezzati, Stephen Begg, Stephen Vander Hoorn, and Alan D. Lopez, "Sensitivity and Uncertainty Analyses for Burden of Disease and Risk Factor Estimates." 2006. Global Burden of Disease and Risk Factors,ed. , 399-426. New York: Oxford University Press. DOI: 10.1596/978-0-8213-6262-4/Chpt-5. | - Uncertainty in very small DALY weights (for less severe effects) affects overall outcomes of DALY calculations much more than uncertainty in large disability weights. This is a "flaw" of the method: if health would be defined as 1 and death as 0 (as is being done with QALYs), the more severe outcomes would have more overall uncertainty. The uncertainty is greatest for the smallest disability weights and narrows as more severe weights are attained (figure 5.16<ref> Colin D. Mathers, Joshua A. Salomon, Majid Ezzati, Stephen Begg, Stephen Vander Hoorn, and Alan D. Lopez, "Sensitivity and Uncertainty Analyses for Burden of Disease and Risk Factor Estimates." 2006. Global Burden of Disease and Risk Factors,ed. , 399-426. New York: Oxford University Press. DOI: 10.1596/978-0-8213-6262-4/Chpt-5. | ||
</ref> | </ref> | ||
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'''Arguments opposing this approach include:''' | '''Arguments opposing this approach include:''' | ||
- Estimates of DALY weights differ between experts, so this variation should be presented in the overall distribution of these weights. | - Estimates of DALY weights differ between experts, so this variation should be presented in the overall distribution of these weights. | ||
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=== Formula === {{disclink|Formula?}} | === Formula === | ||
{{disclink|Formula?}} | |||
*[http://www.who.int/entity/healthinfo/bodreferencedisabilityweights.xls WHO data table] | *[http://www.who.int/entity/healthinfo/bodreferencedisabilityweights.xls WHO data table] |
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DALY weights describe the weights that are given to different diseases in the calculation of disability-adjusted life years.
Scope
DALY weight (also called: disability weight, severity weight) is a number that describes the severity of a disease. It varies from 0 (perfect health) to 1 (death).
Definition
Causality
List of parents:
- No causal parents
Data
Disability weights are obtained by posing two different Person Trade-Off (PTO) questions to expert panels Question 1 compares life extensions for disabled and healthy people Question 2 compares cures for illness with extension of life
Ideally, these values should be derived from empirical data among representative populations. Combining the answers to these questions results in an average disability weight. Usually, these weights are presented as a fixed parameter, without a confidence interval or other type of distribution.
Arguments defending this approach include:
- DALY weights are an intrinsically subjective value for which no "true estimate" exists. They should be treated as a normative value, which does not need further uncertainty intervals.
- Uncertainty in very small DALY weights (for less severe effects) affects overall outcomes of DALY calculations much more than uncertainty in large disability weights. This is a "flaw" of the method: if health would be defined as 1 and death as 0 (as is being done with QALYs), the more severe outcomes would have more overall uncertainty. The uncertainty is greatest for the smallest disability weights and narrows as more severe weights are attained (figure 5.16[1] ).This provides a skewed image. In order to avoid this, distributions should not be used. Another solution might be to normalize the weights. D↷
Arguments opposing this approach include:
- Estimates of DALY weights differ between experts, so this variation should be presented in the overall distribution of these weights.
Including uncertainty intervals of disability weights will probably not affect the ranking of overall disease burden estimates very significantly (WHO GBD study). However, it will affect the confidence interval of individual estimates.
List of data files or sources:
- Disability weights for comorbidity and their influence on Health-adjusted Life Expectancy
- Global Burden of Disease in 2002: data sources, methods and results, page 88
- General WHO info for calculating DALYs
- WHO data table
Formula
Unit
dimensionless (between 0 and 1)
References
- ↑ Colin D. Mathers, Joshua A. Salomon, Majid Ezzati, Stephen Begg, Stephen Vander Hoorn, and Alan D. Lopez, "Sensitivity and Uncertainty Analyses for Burden of Disease and Risk Factor Estimates." 2006. Global Burden of Disease and Risk Factors,ed. , 399-426. New York: Oxford University Press. DOI: 10.1596/978-0-8213-6262-4/Chpt-5.
Result
Annex Table 3. Age-specific disability weights for untreated and treated forms of sequelae included in the Global Burden of Disease Study. | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Untreated form | Treated form | |||||||||||
Age group (years) | Age group (years) | |||||||||||
Sequela | 0-4 | 5-14 | 15-44 | 45-59 | 60+ | 0-4 | 5-14 | 15-44 | 45-59 | 60+ | ||
Tuberculosis | ||||||||||||
HIV sero-negative cases | 0.294 | 0.294 | 0.264 | 0.274 | 0.274 | 0.294 | 0.294 | 0.264 | 0.274 | 0.274 | ||
HIV sero-positive cases | 0.294 | 0.294 | 0.264 | 0.274 | 0.274 | 0.294 | 0.294 | 0.264 | 0.274 | 0.274 | ||
Syphilis | ||||||||||||
Congenital syphilis | 0.315 | 0.315 | 0.315 | 0.315 | 0.315 | 0.315 | 0.315 | 0.315 | 0.315 | 0.315 | ||
Low birth weight | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Primary | 0.015 | 0.015 | 0.015 | 0.014 | 0.014 | 0.015 | 0.015 | 0.015 | 0.014 | 0.014 | ||
Secondary | 0.048 | 0.048 | 0.048 | 0.048 | 0.044 | 0.048 | 0.048 | 0.048 | 0.048 | 0.044 | ||
Tertiary -- Cardiovascular | 0.196 | 0.196 | 0.196 | 0.196 | 0.196 | 0.196 | 0.196 | 0.196 | 0.196 | 0.196 | ||
Tertiary -- Gummas | 0.102 | 0.102 | 0.102 | 0.102 | 0.094 | 0.102 | 0.102 | 0.102 | 0.102 | 0.094 | ||
Tertiary -- Neurologic | 0.283 | 0.283 | 0.283 | 0.283 | 0.283 | 0.283 | 0.283 | 0.283 | 0.283 | 0.283 | ||
Chlamydia | ||||||||||||
Ophthalmia neonatorum | 0.180 | 0.000 | 0.000 | 0.000 | 0.000 | 0.180 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Low birth weight | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Corneal scar -- Blindness | 0.600 | 0.600 | 0.600 | 0.600 | 0.600 | 0.493 | 0.491 | 0.488 | 0.488 | 0.488 | ||
Corneal scar -- Low vision | 0.223 | 0.245 | 0.245 | 0.245 | 0.245 | 0.223 | 0.245 | 0.245 | 0.245 | 0.245 | ||
Cervicitis | 0.049 | 0.049 | 0.049 | 0.049 | 0.049 | 0.049 | 0.049 | 0.049 | 0.049 | 0.049 | ||
Neonatal pneumonia | 0.280 | 0.280 | 0.276 | 0.276 | 0.280 | 0.280 | 0.280 | 0.276 | 0.276 | 0.280 | ||
Pelvic inflammatory disease | 0.420 | 0.420 | 0.420 | 0.420 | 0.420 | 0.169 | 0.169 | 0.169 | 0.169 | 0.169 | ||
Ectopic pregnancy | 0.000 | 0.549 | 0.549 | 0.549 | 0.000 | 0.000 | 0.549 | 0.549 | 0.549 | 0.000 | ||
Tubo-ovarian abscess | 0.000 | 0.549 | 0.549 | 0.549 | 0.000 | 0.000 | 0.549 | 0.549 | 0.549 | 0.000 | ||
Chronic pelvic pain | 0.122 | 0.122 | 0.122 | 0.122 | 0.122 | 0.122 | 0.122 | 0.122 | 0.122 | 0.122 | ||
Infertility | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | ||
Symptomatic urethritis | 0.067 | 0.067 | 0.067 | 0.067 | 0.067 | 0.067 | 0.067 | 0.067 | 0.067 | 0.067 | ||
Epididymitis | 0.167 | 0.167 | 0.167 | 0.167 | 0.167 | 0.167 | 0.167 | 0.167 | 0.167 | 0.167 | ||
Stricture | 0.151 | 0.151 | 0.151 | 0.151 | 0.151 | 0.151 | 0.151 | 0.151 | 0.151 | 0.151 | ||
Gonorrhoea | ||||||||||||
Ophthalmia neonatorum | 0.180 | 0.000 | 0.000 | 0.000 | 0.000 | 0.180 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Low birth weight | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Corneal scar -- Blindness | 0.600 | 0.000 | 0.000 | 0.000 | 0.000 | 0.600 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Corneal scar -- Low vision | 0.223 | 0.245 | 0.245 | 0.245 | 0.245 | 0.223 | 0.245 | 0.245 | 0.245 | 0.245 | ||
Cervicitis | 0.049 | 0.049 | 0.049 | 0.049 | 0.049 | 0.049 | 0.049 | 0.049 | 0.049 | 0.049 | ||
Pelvic inflammatory disease | 0.169 | 0.169 | 0.169 | 0.169 | 0.169 | 0.169 | 0.169 | 0.169 | 0.169 | 0.169 | ||
Ectopic pregnancy | 0.000 | 0.549 | 0.549 | 0.549 | 0.000 | 0.000 | 0.549 | 0.549 | 0.549 | 0.000 | ||
Tubo-ovarian abscess | 0.000 | 0.549 | 0.549 | 0.549 | 0.000 | 0.000 | 0.549 | 0.549 | 0.549 | 0.000 | ||
Chronic pelvic pain | 0.122 | 0.122 | 0.122 | 0.122 | 0.122 | 0.122 | 0.122 | 0.122 | 0.122 | 0.122 | ||
Infertility | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | ||
Symptomatic urethritis | 0.067 | 0.067 | 0.067 | 0.067 | 0.067 | 0.067 | 0.067 | 0.067 | 0.067 | 0.067 | ||
Epididymitis | 0.167 | 0.167 | 0.167 | 0.167 | 0.167 | 0.167 | 0.167 | 0.167 | 0.167 | 0.167 | ||
Stricture | 0.151 | 0.151 | 0.151 | 0.151 | 0.151 | 0.151 | 0.151 | 0.151 | 0.151 | 0.151 | ||
HIV | ||||||||||||
Cases | 0.123 | 0.123 | 0.136 | 0.136 | 0.136 | 0.123 | 0.123 | 0.136 | 0.136 | 0.136 | ||
AIDS | 0.505 | 0.505 | 0.505 | 0.505 | 0.505 | 0.505 | 0.505 | 0.505 | 0.505 | 0.505 | ||
Diarrhoeal diseases -- Episodes | 0.119 | 0.094 | 0.086 | 0.086 | 0.088 | 0.119 | 0.094 | 0.086 | 0.086 | 0.088 | ||
Pertussis | ||||||||||||
Episodes | 0.178 | 0.166 | 0.156 | 0.156 | 0.156 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Mental retardation | 0.469 | 0.483 | 0.483 | 0.486 | 0.485 | 0.394 | 0.420 | 0.451 | 0.466 | 0.468 | ||
Poliomyelitis -- Lameness | 0.369 | 0.369 | 0.369 | 0.369 | 0.369 | 0.369 | 0.369 | 0.369 | 0.369 | 0.369 | ||
Diphtheria | ||||||||||||
Episodes | 0.231 | 0.230 | 0.230 | 0.230 | 0.230 | 0.231 | 0.230 | 0.230 | 0.230 | 0.230 | ||
Neurological complications | 0.078 | 0.078 | 0.078 | 0.078 | 0.078 | 0.078 | 0.078 | 0.078 | 0.078 | 0.078 | ||
Myocarditis | 0.323 | 0.323 | 0.323 | 0.323 | 0.323 | 0.323 | 0.323 | 0.323 | 0.323 | 0.323 | ||
Measles -- Episodes | 0.152 | 0.152 | 0.152 | 0.152 | 0.152 | 0.152 | 0.152 | 0.152 | 0.152 | 0.152 | ||
Tetanus -- Episodes | 0.640 | 0.640 | 0.610 | 0.604 | 0.612 | 0.640 | 0.640 | 0.610 | 0.604 | 0.612 | ||
Bacterial meningitis, meningococcaemia | ||||||||||||
Streptococcus pneumoniae -- Episodes | 0.616 | 0.616 | 0.613 | 0.613 | 0.613 | 0.616 | 0.616 | 0.613 | 0.613 | 0.613 | ||
Haemophilus influenzae -- Episodes | 0.616 | 0.616 | 0.613 | 0.613 | 0.613 | 0.616 | 0.616 | 0.613 | 0.613 | 0.613 | ||
Neisseria meningitidis -- Episodes | 0.616 | 0.616 | 0.613 | 0.613 | 0.613 | 0.616 | 0.616 | 0.613 | 0.613 | 0.613 | ||
Meningococcaemia without meningitis -- | ||||||||||||
Episodes | 0.152 | 0.152 | 0.152 | 0.152 | 0.152 | 0.152 | 0.152 | 0.152 | 0.152 | 0.152 | ||
Deafness | 0.233 | 0.227 | 0.216 | 0.215 | 0.213 | 0.175 | 0.169 | 0.168 | 0.168 | 0.168 | ||
Seizure disorder | 0.099 | 0.150 | 0.150 | 0.150 | 0.150 | 0.041 | 0.065 | 0.065 | 0.065 | 0.065 | ||
Motor deficit | 0.388 | 0.388 | 0.388 | 0.397 | 0.468 | 0.334 | 0.334 | 0.334 | 0.337 | 0.390 | ||
Mental retardation | 0.469 | 0.483 | 0.483 | 0.486 | 0.485 | 0.394 | 0.420 | 0.451 | 0.466 | 0.468 | ||
Hepatitis B and hepatitis C -- Episodes | 0.170 | 0.181 | 0.209 | 0.212 | 0.212 | 0.170 | 0.181 | 0.209 | 0.212 | 0.212 | ||
Malaria | ||||||||||||
Episodes | 0.211 | 0.195 | 0.172 | 0.172 | 0.172 | 0.211 | 0.195 | 0.172 | 0.172 | 0.172 | ||
Anaemia | 0.012 | 0.012 | 0.012 | 0.013 | 0.012 | 0.012 | 0.012 | 0.012 | 0.013 | 0.012 | ||
Neurological sequelae | 0.473 | 0.473 | 0.473 | 0.473 | 0.473 | 0.436 | 0.435 | 0.435 | 0.435 | 0.435 | ||
Trypanosomiasis -- Episodes | 0.350 | 0.350 | 0.350 | 0.350 | 0.350 | 0.350 | 0.350 | 0.350 | 0.350 | 0.350 | ||
Chagas disease | ||||||||||||
Infection | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Cardiomyopathy without congestive | ||||||||||||
heart failure | 0.062 | 0.062 | 0.062 | 0.062 | 0.062 | 0.062 | 0.062 | 0.062 | 0.062 | 0.062 | ||
Cardiomyopathy with congestive | ||||||||||||
heart failure | 0.323 | 0.323 | 0.323 | 0.323 | 0.323 | 0.171 | 0.171 | 0.171 | 0.171 | 0.171 | ||
Megaviscera | 0.240 | 0.240 | 0.240 | 0.240 | 0.240 | 0.240 | 0.240 | 0.240 | 0.240 | 0.240 | ||
Schistosomiasis -- Infection | 0.005 | 0.005 | 0.006 | 0.006 | 0.006 | 0.005 | 0.005 | 0.006 | 0.006 | 0.006 | ||
Leishmaniasis | ||||||||||||
Visceral | 0.243 | 0.243 | 0.243 | 0.243 | 0.243 | 0.243 | 0.243 | 0.243 | 0.243 | 0.243 | ||
Cutaneous | 0.023 | 0.023 | 0.023 | 0.023 | 0.023 | 0.023 | 0.023 | 0.023 | 0.023 | 0.023 | ||
Lymphatic filariasis | ||||||||||||
Hydrocele >15 cm | 0.066 | 0.070 | 0.075 | 0.075 | 0.075 | 0.066 | 0.070 | 0.075 | 0.075 | 0.075 | ||
Bancroftian lymphoedema | 0.067 | 0.080 | 0.113 | 0.128 | 0.119 | 0.067 | 0.080 | 0.113 | 0.128 | 0.119 | ||
Brugian lymphoedema | 0.064 | 0.080 | 0.113 | 0.128 | 0.119 | 0.064 | 0.080 | 0.113 | 0.128 | 0.119 | ||
Onchocerciasis | ||||||||||||
Blindness | 0.600 | 0.600 | 0.600 | 0.600 | 0.600 | 0.493 | 0.491 | 0.488 | 0.488 | 0.488 | ||
Itching | 0.068 | 0.068 | 0.068 | 0.068 | 0.068 | 0.068 | 0.068 | 0.068 | 0.068 | 0.068 | ||
Low vision | 0.223 | 0.245 | 0.245 | 0.245 | 0.245 | 0.223 | 0.245 | 0.245 | 0.245 | 0.245 | ||
Leprosy | ||||||||||||
Cases | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Disabling leprosy | 0.153 | 0.153 | 0.153 | 0.153 | 0.153 | 0.153 | 0.153 | 0.153 | 0.153 | 0.153 | ||
Dengue | ||||||||||||
Dengue haemorrhagic fever | 0.211 | 0.195 | 0.172 | 0.172 | 0.172 | 0.211 | 0.195 | 0.172 | 0.172 | 0.172 | ||
Japanese encephalitis | ||||||||||||
Episodes | 0.616 | 0.616 | 0.613 | 0.613 | 0.613 | 0.616 | 0.616 | 0.613 | 0.613 | 0.613 | ||
Cognitive impairment | 0.469 | 0.483 | 0.483 | 0.486 | 0.485 | 0.394 | 0.420 | 0.451 | 0.466 | 0.468 | ||
Neurological sequelae | 0.388 | 0.388 | 0.388 | 0.397 | 0.468 | 0.334 | 0.334 | 0.334 | 0.337 | 0.390 | ||
Trachoma | ||||||||||||
Blindness | 0.600 | 0.600 | 0.600 | 0.600 | 0.600 | 0.493 | 0.491 | 0.488 | 0.488 | 0.488 | ||
Low Vision | 0.223 | 0.245 | 0.245 | 0.245 | 0.245 | 0.223 | 0.245 | 0.245 | 0.245 | 0.245 | ||
Ascariasis | ||||||||||||
High intensity infection | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Cotemporaneous cognitive deficit | 0.006 | 0.006 | 0.006 | 0.006 | 0.006 | 0.006 | 0.006 | 0.006 | 0.006 | 0.006 | ||
Cognitive impairment | 0.463 | 0.463 | 0.463 | 0.463 | 0.463 | 0.463 | 0.463 | 0.463 | 0.463 | 0.463 | ||
Intestinal obstruction | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | ||
Trichuriasis | ||||||||||||
High intensity infection | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Cotemporaneous cognitive deficit | 0.006 | 0.006 | 0.006 | 0.006 | 0.006 | 0.006 | 0.006 | 0.006 | 0.006 | 0.006 | ||
Massive dysentery syndrome | 0.138 | 0.116 | 0.114 | 0.114 | 0.129 | 0.138 | 0.116 | 0.114 | 0.114 | 0.129 | ||
Cognitive impairment | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | ||
Ancylostomiasis and necatoriasis | ||||||||||||
High intensity infection | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Anaemia | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | ||
Cognitive impairment | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | ||
Lower respiratory infections | ||||||||||||
Episodes | 0.280 | 0.280 | 0.276 | 0.276 | 0.280 | 0.280 | 0.280 | 0.276 | 0.276 | 0.280 | ||
Chronic sequelae | 0.099 | 0.099 | 0.099 | 0.099 | 0.099 | 0.099 | 0.099 | 0.099 | 0.099 | 0.099 | ||
Upper respiratory infections | ||||||||||||
Episodes | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Pharyngitis | 0.070 | 0.070 | 0.070 | 0.070 | 0.070 | 0.070 | 0.070 | 0.070 | 0.070 | 0.070 | ||
Otitis media | ||||||||||||
Episodes | 0.023 | 0.023 | 0.023 | 0.023 | 0.023 | 0.023 | 0.023 | 0.023 | 0.023 | 0.023 | ||
Deafness | 0.233 | 0.227 | 0.216 | 0.215 | 0.213 | 0.175 | 0.169 | 0.168 | 0.168 | 0.168 | ||
Maternal haemorrhage | ||||||||||||
Episodes | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Sheehan syndrome | 0.065 | 0.065 | 0.065 | 0.065 | 0.065 | 0.065 | 0.065 | 0.065 | 0.065 | 0.065 | ||
Severe anaemia | 0.087 | 0.087 | 0.093 | 0.090 | 0.087 | 0.087 | 0.087 | 0.093 | 0.090 | 0.087 | ||
Maternal sepsis | ||||||||||||
Episodes | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Infertility | 0.000 | 0.000 | 0.180 | 0.000 | 0.000 | 0.000 | 0.000 | 0.180 | 0.000 | 0.000 | ||
Hypertensive disorders of pregnancy | ||||||||||||
Episodes | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Neurological sequelae | 0.388 | 0.388 | 0.388 | 0.397 | 0.468 | 0.388 | 0.388 | 0.388 | 0.397 | 0.468 | ||
Obstructed labour | ||||||||||||
Episodes | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Stress incontinence | 0.025 | 0.025 | 0.025 | 0.025 | 0.033 | 0.025 | 0.025 | 0.025 | 0.025 | 0.033 | ||
Rectovaginal fistula | 0.000 | 0.000 | 0.430 | 0.000 | 0.000 | 0.000 | 0.000 | 0.430 | 0.000 | 0.000 | ||
Abortion | ||||||||||||
Episodes | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Infertility | 0.000 | 0.000 | 0.180 | 0.000 | 0.000 | 0.000 | 0.000 | 0.180 | 0.000 | 0.000 | ||
Low birth weight -- All sequelae | 0.291 | 0.291 | 0.291 | 0.291 | 0.291 | 0.256 | 0.256 | 0.256 | 0.256 | 0.256 | ||
Birth asphyxia and birth trauma -- | ||||||||||||
All sequelae | 0.381 | 0.381 | 0.381 | 0.381 | 0.381 | 0.334 | 0.334 | 0.334 | 0.334 | 0.334 | ||
Protein-energy malnutrition | ||||||||||||
Wasting | 0.053 | 0.000 | 0.000 | 0.000 | 0.000 | 0.053 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Stunting | 0.002 | 0.000 | 0.000 | 0.000 | 0.000 | 0.002 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Developmental disability | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | ||
Iodine deficiency | ||||||||||||
Goitre -- grade 0 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Goitre -- grade 1 | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | ||
Goitre -- grade 2 | 0.025 | 0.025 | 0.025 | 0.025 | 0.025 | 0.025 | 0.025 | 0.025 | 0.025 | 0.025 | ||
Mild developmental disability | 0.006 | 0.006 | 0.006 | 0.006 | 0.006 | 0.006 | 0.006 | 0.006 | 0.006 | 0.006 | ||
Cretinoidism | 0.255 | 0.255 | 0.255 | 0.255 | 0.255 | 0.255 | 0.255 | 0.255 | 0.255 | 0.255 | ||
Cretinism | 0.804 | 0.804 | 0.804 | 0.804 | 0.804 | 0.804 | 0.804 | 0.804 | 0.804 | 0.804 | ||
Vitamin A deficiency | ||||||||||||
Xerophthalmia | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Corneal scar | 0.274 | 0.282 | 0.282 | 0.282 | 0.282 | 0.274 | 0.282 | 0.282 | 0.282 | 0.282 | ||
Iron-deficiency anaemia | ||||||||||||
Mild | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Moderate | 0.011 | 0.011 | 0.011 | 0.012 | 0.012 | 0.011 | 0.011 | 0.011 | 0.012 | 0.012 | ||
Severe | 0.087 | 0.087 | 0.093 | 0.090 | 0.087 | 0.087 | 0.087 | 0.093 | 0.090 | 0.087 | ||
Very severe | 0.241 | 0.244 | 0.255 | 0.252 | 0.252 | 0.241 | 0.244 | 0.255 | 0.252 | 0.252 | ||
Cognitive impairment | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | 0.024 | ||
Cancers -- Preterminal | ||||||||||||
Mouth and oropharynx | 0.145 | 0.145 | 0.145 | 0.145 | 0.145 | 0.090 | 0.090 | 0.090 | 0.090 | 0.090 | ||
Oesophagus | 0.217 | 0.217 | 0.217 | 0.217 | 0.217 | 0.217 | 0.217 | 0.217 | 0.217 | 0.217 | ||
Stomach | 0.217 | 0.217 | 0.217 | 0.217 | 0.217 | 0.217 | 0.217 | 0.217 | 0.217 | 0.217 | ||
Colon and rectum | 0.217 | 0.217 | 0.217 | 0.217 | 0.217 | 0.217 | 0.217 | 0.217 | 0.217 | 0.217 | ||
Liver | 0.239 | 0.239 | 0.239 | 0.239 | 0.239 | 0.239 | 0.239 | 0.239 | 0.239 | 0.239 | ||
Pancreas | 0.301 | 0.301 | 0.301 | 0.301 | 0.301 | 0.237 | 0.237 | 0.237 | 0.237 | 0.237 | ||
Trachea, bronchus and lung | 0.146 | 0.146 | 0.146 | 0.146 | 0.146 | 0.146 | 0.146 | 0.146 | 0.146 | 0.146 | ||
Melanoma and other skin | 0.045 | 0.045 | 0.045 | 0.045 | 0.045 | 0.045 | 0.045 | 0.045 | 0.045 | 0.045 | ||
Breast | 0.069 | 0.069 | 0.069 | 0.069 | 0.069 | 0.086 | 0.086 | 0.086 | 0.086 | 0.086 | ||
Cervix uteri | 0.066 | 0.066 | 0.066 | 0.066 | 0.066 | 0.075 | 0.075 | 0.075 | 0.075 | 0.075 | ||
Corpus uteri | 0.066 | 0.066 | 0.066 | 0.066 | 0.066 | 0.099 | 0.104 | 0.104 | 0.096 | 0.079 | ||
Ovary | 0.081 | 0.081 | 0.081 | 0.081 | 0.081 | 0.097 | 0.097 | 0.097 | 0.084 | 0.059 | ||
Prostate | 0.113 | 0.113 | 0.113 | 0.113 | 0.113 | 0.134 | 0.134 | 0.134 | 0.134 | 0.134 | ||
Bladder | 0.085 | 0.085 | 0.085 | 0.085 | 0.085 | 0.087 | 0.087 | 0.087 | 0.087 | 0.085 | ||
Lymphomas and multiple myeloma | 0.089 | 0.089 | 0.089 | 0.089 | 0.089 | 0.057 | 0.057 | 0.057 | 0.057 | 0.057 | ||
Leukaemia | 0.098 | 0.098 | 0.108 | 0.112 | 0.112 | 0.083 | 0.083 | 0.093 | 0.097 | 0.097 | ||
Cancers -- Terminal | 0.809 | 0.809 | 0.809 | 0.809 | 0.809 | 0.809 | 0.809 | 0.809 | 0.809 | 0.809 | ||
Diabetes mellitus | ||||||||||||
Cases | 0.012 | 0.012 | 0.012 | 0.012 | 0.012 | 0.033 | 0.033 | 0.033 | 0.033 | 0.033 | ||
Diabetic foot | 0.137 | 0.137 | 0.137 | 0.137 | 0.137 | 0.129 | 0.129 | 0.129 | 0.129 | 0.129 | ||
Neuropathy | 0.078 | 0.078 | 0.078 | 0.078 | 0.078 | 0.064 | 0.064 | 0.064 | 0.064 | 0.064 | ||
Retinopathy -- Blindness | 0.600 | 0.600 | 0.600 | 0.600 | 0.600 | 0.493 | 0.491 | 0.488 | 0.488 | 0.488 | ||
Amputation | 0.155 | 0.155 | 0.155 | 0.155 | 0.155 | 0.068 | 0.068 | 0.068 | 0.068 | 0.068 | ||
Unipolar major depression -- episodes | 0.600 | 0.600 | 0.600 | 0.600 | 0.600 | 0.302 | 0.302 | 0.302 | 0.302 | 0.302 | ||
Bipolar disorder -- Cases | 0.583 | 0.583 | 0.583 | 0.583 | 0.583 | 0.383 | 0.383 | 0.383 | 0.383 | 0.383 | ||
Schizophrenia -- Cases | 0.627 | 0.627 | 0.627 | 0.645 | 0.667 | 0.351 | 0.351 | 0.351 | 0.351 | 0.351 | ||
Epilepsy -- Cases | 0.099 | 0.150 | 0.150 | 0.150 | 0.150 | 0.041 | 0.065 | 0.065 | 0.065 | 0.065 | ||
Alcohol use -- | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | ||
Alcohol dependence syndrome | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | ||
Dementia -- Cases | 0.627 | 0.627 | 0.627 | 0.645 | 0.667 | 0.627 | 0.627 | 0.627 | 0.645 | 0.667 | ||
Parkinson disease -- Cases | 0.392 | 0.392 | 0.392 | 0.392 | 0.406 | 0.316 | 0.316 | 0.316 | 0.316 | 0.332 | ||
Multiple sclerosis -- Cases | 0.410 | 0.410 | 0.410 | 0.420 | 0.437 | 0.410 | 0.410 | 0.410 | 0.420 | 0.437 | ||
Drug use -- | ||||||||||||
Dysfunctional and harmful drug use | 0.252 | 0.252 | 0.250 | 0.250 | 0.250 | 0.252 | 0.252 | 0.250 | 0.250 | 0.250 | ||
Post-traumatic stress disorder -- Cases | 0.105 | 0.105 | 0.108 | 0.108 | 0.108 | 0.105 | 0.105 | 0.108 | 0.108 | 0.108 | ||
Obsessive-compulsive disorders -- | ||||||||||||
Cases | 0.129 | 0.129 | 0.129 | 0.129 | 0.129 | 0.080 | 0.080 | 0.080 | 0.080 | 0.080 | ||
Panic disorder -- Cases | 0.173 | 0.173 | 0.173 | 0.173 | 0.173 | 0.091 | 0.091 | 0.091 | 0.091 | 0.091 | ||
Glaucoma -- Blindness | 0.600 | 0.600 | 0.600 | 0.600 | 0.600 | 0.600 | 0.600 | 0.600 | 0.600 | 0.600 | ||
Cataracts -- Blindness | 0.600 | 0.600 | 0.600 | 0.600 | 0.600 | 0.493 | 0.491 | 0.488 | 0.488 | 0.488 | ||
Rheumatic heart disease -- | ||||||||||||
Congestive heart failure | 0.323 | 0.323 | 0.323 | 0.323 | 0.323 | 0.171 | 0.171 | 0.171 | 0.171 | 0.171 | ||
Ischaemic heart disease | ||||||||||||
Acute myocardial infarction | 0.491 | 0.491 | 0.491 | 0.491 | 0.491 | 0.395 | 0.395 | 0.395 | 0.395 | 0.395 | ||
Angina pectoris | 0.227 | 0.227 | 0.227 | 0.227 | 0.227 | 0.095 | 0.095 | 0.095 | 0.095 | 0.095 | ||
Congestive heart failure | 0.323 | 0.323 | 0.323 | 0.323 | 0.323 | 0.171 | 0.171 | 0.171 | 0.171 | 0.171 | ||
Cerebrovascular disease -- | ||||||||||||
First-ever stroke | 0.262 | 0.262 | 0.262 | 0.268 | 0.301 | 0.224 | 0.224 | 0.224 | 0.224 | 0.258 | ||
Inflammatory heart diseases | ||||||||||||
Myocarditis | 0.323 | 0.323 | 0.323 | 0.323 | 0.323 | 0.171 | 0.171 | 0.171 | 0.171 | 0.171 | ||
Pericarditis | 0.323 | 0.323 | 0.323 | 0.323 | 0.323 | 0.171 | 0.171 | 0.171 | 0.171 | 0.171 | ||
Endocarditis | 0.323 | 0.323 | 0.323 | 0.323 | 0.323 | 0.171 | 0.171 | 0.171 | 0.171 | 0.171 | ||
Cardiomyopathy | 0.323 | 0.323 | 0.323 | 0.323 | 0.323 | 0.171 | 0.171 | 0.171 | 0.171 | 0.171 | ||
COPD -- Symptomatic cases | 0.428 | 0.428 | 0.428 | 0.428 | 0.428 | 0.388 | 0.388 | 0.388 | 0.388 | 0.388 | ||
Asthma -- Cases | 0.099 | 0.099 | 0.099 | 0.099 | 0.099 | 0.059 | 0.059 | 0.059 | 0.059 | 0.059 | ||
Peptic ulcer -- Cases | 0.115 | 0.115 | 0.115 | 0.115 | 0.115 | 0.003 | 0.003 | 0.003 | 0.003 | 0.003 | ||
Cirrhosis of the liver -- | ||||||||||||
Symptomatic cases | 0.330 | 0.330 | 0.330 | 0.330 | 0.330 | 0.330 | 0.330 | 0.330 | 0.330 | 0.330 | ||
Appendicitis -- Episodes | 0.463 | 0.463 | 0.463 | 0.463 | 0.463 | 0.463 | 0.463 | 0.463 | 0.463 | 0.463 | ||
Nephritis and nephrosis | ||||||||||||
Acute glomerulonephritis | 0.082 | 0.082 | 0.104 | 0.104 | 0.104 | 0.107 | 0.107 | 0.107 | 0.096 | 0.096 | ||
End-stage renal disease | 0.082 | 0.082 | 0.104 | 0.104 | 0.104 | 0.107 | 0.107 | 0.107 | 0.096 | 0.096 | ||
Benign prostatic hypertrophy -- | ||||||||||||
Symptomatic cases | 0.038 | 0.038 | 0.038 | 0.038 | 0.038 | 0.038 | 0.038 | 0.038 | 0.038 | 0.038 | ||
Rheumatoid arthritis -- Cases | 0.233 | 0.233 | 0.233 | 0.233 | 0.233 | 0.174 | 0.174 | 0.174 | 0.174 | 0.174 | ||
Osteoarthritis | ||||||||||||
Hip | 0.156 | 0.156 | 0.156 | 0.156 | 0.156 | 0.108 | 0.108 | 0.108 | 0.108 | 0.108 | ||
Knee | 0.156 | 0.156 | 0.156 | 0.156 | 0.156 | 0.108 | 0.108 | 0.108 | 0.108 | 0.108 | ||
Congenital anomalies | ||||||||||||
Abdominal wall defect -- Cases | 0.850 | 0.000 | 0.000 | 0.000 | 0.000 | 0.850 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Anencephaly -- Cases | 0.850 | 0.000 | 0.000 | 0.000 | 0.000 | 0.850 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Anorectal atresia -- Cases | 0.850 | 0.000 | 0.000 | 0.000 | 0.000 | 0.850 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Cleft lip -- Cases | 0.098 | 0.000 | 0.000 | 0.000 | 0.000 | 0.016 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Cleft palate -- Cases | 0.231 | 0.000 | 0.000 | 0.000 | 0.000 | 0.015 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Oesophageal atresia -- Cases | 0.850 | 0.000 | 0.000 | 0.000 | 0.000 | 0.850 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Renal agenesis -- Cases | 0.850 | 0.000 | 0.000 | 0.000 | 0.000 | 0.850 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Down syndrome -- Cases | 0.593 | 0.593 | 0.593 | 0.593 | 0.593 | 0.593 | 0.593 | 0.593 | 0.593 | 0.593 | ||
Congenital heart anomalies -- Cases | 0.323 | 0.323 | 0.323 | 0.323 | 0.323 | 0.323 | 0.323 | 0.323 | 0.323 | 0.323 | ||
Spina bifida -- Cases | 0.593 | 0.593 | 0.593 | 0.593 | 0.593 | 0.593 | 0.593 | 0.593 | 0.593 | 0.593 | ||
Dental caries -- Episodes | 0.081 | 0.081 | 0.081 | 0.081 | 0.081 | 0.081 | 0.081 | 0.081 | 0.081 | 0.081 | ||
Periodontal disease -- Episodes | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | ||
Edentulism -- Cases | 0.061 | 0.061 | 0.061 | 0.061 | 0.061 | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | ||
Drownings | ||||||||||||
Episodes | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | ||
Quadriplegia | 0.005 | 0.005 | 0.005 | 0.005 | 0.005 | 0.005 | 0.005 | 0.005 | 0.005 | 0.005 | ||
Poisoning -- Episodes | 0.611 | 0.611 | 0.607 | 0.607 | 0.607 | 0.611 | 0.611 | 0.607 | 0.607 | 0.607 | ||
Fractures | ||||||||||||
Skull -- Short term | 0.431 | 0.431 | 0.431 | 0.431 | 0.431 | 0.431 | 0.431 | 0.431 | 0.431 | 0.431 | ||
Skull -- Long term | 0.411 | 0.411 | 0.411 | 0.410 | 0.395 | 0.350 | 0.350 | 0.350 | 0.350 | 0.404 | ||
Face bones | 0.223 | 0.223 | 0.223 | 0.223 | 0.223 | 0.223 | 0.223 | 0.223 | 0.223 | 0.223 | ||
Vertebral column | 0.266 | 0.266 | 0.266 | 0.266 | 0.266 | 0.266 | 0.266 | 0.266 | 0.266 | 0.266 | ||
Injured spinal cord | 0.725 | 0.725 | 0.725 | 0.725 | 0.725 | 0.725 | 0.725 | 0.725 | 0.725 | 0.725 | ||
Fractures | ||||||||||||
Rib or sternum | 0.199 | 0.199 | 0.199 | 0.199 | 0.199 | 0.199 | 0.199 | 0.199 | 0.199 | 0.199 | ||
Pelvis | 0.247 | 0.247 | 0.247 | 0.247 | 0.247 | 0.247 | 0.247 | 0.247 | 0.247 | 0.247 | ||
Clavicle, scapula, or humerus | 0.153 | 0.153 | 0.137 | 0.137 | 0.137 | 0.153 | 0.153 | 0.137 | 0.137 | 0.137 | ||
Radius or ulna | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | 0.180 | ||
Hand bones | 0.100 | 0.100 | 0.100 | 0.100 | 0.100 | 0.100 | 0.100 | 0.100 | 0.100 | 0.100 | ||
Femur -- Short term | 0.372 | 0.372 | 0.372 | 0.372 | 0.372 | 0.372 | 0.372 | 0.372 | 0.372 | 0.372 | ||
Femur -- Long term | 0.272 | 0.272 | 0.272 | 0.272 | 0.272 | 0.272 | 0.272 | 0.272 | 0.272 | 0.272 | ||
Patella, tibia, or fibula | 0.271 | 0.271 | 0.271 | 0.271 | 0.271 | 0.271 | 0.271 | 0.271 | 0.271 | 0.271 | ||
Ankle | 0.196 | 0.196 | 0.196 | 0.196 | 0.196 | 0.196 | 0.196 | 0.196 | 0.196 | 0.196 | ||
Foot bones | 0.077 | 0.077 | 0.077 | 0.077 | 0.077 | 0.077 | 0.077 | 0.077 | 0.077 | 0.077 | ||
Dislocated shoulder, elbow, or hip | 0.074 | 0.074 | 0.074 | 0.074 | 0.074 | 0.074 | 0.074 | 0.074 | 0.074 | 0.074 | ||
Sprains | 0.064 | 0.064 | 0.064 | 0.064 | 0.064 | 0.064 | 0.064 | 0.064 | 0.064 | 0.064 | ||
Intracranial injury | ||||||||||||
Short term | 0.359 | 0.359 | 0.359 | 0.359 | 0.359 | 0.359 | 0.359 | 0.359 | 0.359 | 0.359 | ||
Long term | 0.359 | 0.359 | 0.359 | 0.359 | 0.359 | 0.359 | 0.359 | 0.359 | 0.359 | 0.359 | ||
Internal injuries | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.208 | 0.208 | 0.208 | 0.208 | 0.208 | ||
Open wound | 0.108 | 0.108 | 0.108 | 0.108 | 0.108 | 0.108 | 0.108 | 0.108 | 0.108 | 0.108 | ||
Injury to eyes | 0.354 | 0.354 | 0.354 | 0.354 | 0.354 | 0.301 | 0.300 | 0.299 | 0.299 | 0.299 | ||
Amputations | ||||||||||||
Thumb | 0.165 | 0.165 | 0.165 | 0.165 | 0.165 | 0.165 | 0.165 | 0.165 | 0.165 | 0.165 | ||
Finger | 0.102 | 0.102 | 0.102 | 0.102 | 0.102 | 0.102 | 0.102 | 0.102 | 0.102 | 0.102 | ||
Arm | 0.102 | 0.102 | 0.102 | 0.102 | 0.102 | 0.102 | 0.102 | 0.102 | 0.102 | 0.102 | ||
Toe | 0.078 | 0.078 | 0.078 | 0.078 | 0.078 | 0.064 | 0.064 | 0.064 | 0.064 | 0.064 | ||
Foot | 0.300 | 0.300 | 0.300 | 0.300 | 0.300 | 0.300 | 0.300 | 0.300 | 0.300 | 0.300 | ||
Leg | 0.300 | 0.300 | 0.300 | 0.300 | 0.300 | 0.300 | 0.300 | 0.300 | 0.300 | 0.300 | ||
Crushing | 0.218 | 0.218 | 0.218 | 0.218 | 0.218 | 0.218 | 0.218 | 0.218 | 0.218 | 0.218 | ||
Burns | ||||||||||||
<20% -- Short term | 0.186 | 0.186 | 0.186 | 0.186 | 0.186 | 0.158 | 0.158 | 0.158 | 0.158 | 0.158 | ||
<20% -- Long term | 0.041 | 0.041 | 0.041 | 0.041 | 0.041 | 0.011 | 0.011 | 0.011 | 0.011 | 0.011 | ||
>20% and <60% -- Short term | 0.469 | 0.469 | 0.469 | 0.469 | 0.469 | 0.441 | 0.441 | 0.441 | 0.441 | 0.441 | ||
>20% and <60% -- Long term | 0.255 | 0.255 | 0.255 | 0.255 | 0.255 | 0.255 | 0.255 | 0.255 | 0.255 | 0.255 | ||
>60% -- Short term | 0.469 | 0.469 | 0.469 | 0.469 | 0.469 | 0.441 | 0.441 | 0.441 | 0.441 | 0.441 | ||
>60% -- Long term | 0.255 | 0.255 | 0.255 | 0.255 | 0.255 | 0.255 | 0.255 | 0.255 | 0.255 | 0.255 | ||
Injured nerves | 0.078 | 0.078 | 0.078 | 0.078 | 0.078 | 0.064 | 0.064 | 0.064 | 0.064 | 0.064 |