Myocardial infarction risk in adults in Beneris

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Scope
Myocardial infarction risk in adults in Beneris describes the relationship between exposure to omega-3 fatty acids (EPA+DHA) and methyl mercury (MeHg) in fish and the mortality from coronary heart disease (CHD) in adult Beneris population.

Definition

Myocardial infarction in adults is represented as a function of parent variables and is indexed by variable age. It applies to two age groups, i.e adults aged 18-55yr and 55yr+ (gender combined).

Causality

List of parents:

• Mortality in Finland - represents baseline CHD mortality in Finland
• Fish oil intake in Beneris
• Methyl mercury intake from fish in Beneris
• ERF of omega-3 fatty acids on CVD risk in adults
• ERF of methyl mercury on CVD risk in adults

Data

Baseline CHD mortality represents the annual CHD mortality rate in Finland in 2006. It is estimated based on Mortality in Finland and equals to 1.5 and 72 cases per 10,000 person-years in age groups 18-55yr and 55yr+, respectively.

Formula

CHD_Mortality = Baseline_CHD_mortality*exp[ERF_of_MeHg*(MeHg_Intake_Fish-Average_MeHg_Intake_Fish)+ if(n3_Intake_Fish*BW<=250,ERF1_of_n3_Fish_Intake*(n3_Intake_Fish-Average_n3_Intake_Fish1), ERF2_of_n3_Fish_Intake*(n3_Intake_Fish-Average_n3_Intake_Fish2))]

Unit

#cases per 10,000 person-years