Case burden

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Case burden is the burden of disease or other impact that can be attributed to one case or unit, e.g. disease burden per one case of cancer. Typically it is calculated as

case burden = disability weight caused by the disease * duration of the disease.

Case burden can also be monetary losses attributed one case.

For case burdens attributed to waterborne diseases, see Case burden of waterborne microbes.

Question

What are the case burdens (in DALYs or euros) of relevant environmental health outcomes?

Rationale

Data

The case burdens are presented as DALYs or euros per case of illness.

Case burdens of environmental health outcomes(unit/case)

Obs	Response	Subgroup	Disability weight	Duration	Measure	Unit	Case burden	Description
1	Annual number of days with bronchitis in children (age 6-12 years)		0.225	0.00274	BoD	DALY/case	0.00062	WHO 2017a
2	Incidence chronic bronchitis in adults (age 18+ years)		0.099	10	BoD	DALY/case	0.99	Heimtsa & Intarese 2011
3	Incidence of asthma symptoms in asthmatic children (age 5-19 years)		0.07	0.00274	BoD	DALY/case	0.00019	Heimtsa & Intarese 2011
4	Hospitalizations, cardiovascular diseases		0.588	0.038	BoD	DALY/case	0.0223	Bachmann & van der Kamp 2017
5	Hospitalizations, respiratory diseases		0.408	0.038	BoD	DALY/case	0.0155	Bachmann & van der Kamp 2017
6	Work days lost, working age population (age 20-65 years)		0.099	0.00274	BoD	DALY/case	0.00027126	Heimtsa & Intarese 2011
7	Lung cancer (age 30+ years)		0.451	1	BoD	DALY/case	0.451	WHO 2017a
8	Annual number of days with bronchitis in children (age 6-12 years)				Cost	€/case	49	Holland 2014
9	Incidence chronic bronchitis in adults (age 18+ years)				Cost	€/case	62712	Holland 2014
10	Incidence of asthma symptoms in asthmatic children (age 5-19 years)				Cost	€/case	49	Holland 2014
11	Hospitalizations, cardiovascular diseases				Cost	€/case	2574	Holland 2014
12	Hospitalizations, respiratory diseases				Cost	€/case	2574	Holland 2014
13	Work days lost, working age population (age 20-65 years)				Cost	€/case	152	Holland 2014
14	Post-neonatal mortality (age 1-12 months)		1	80	BoD	DALY/case	80	Heimtsa & Intarese 2011
15	Premature deaths due to air pollution		1	10.6	BoD	DALY/case	10.6	De Leeuw & Horálek 2016/5
16	Cost of DALY				Cost	€/DALY	67500	Holland 2014
17	Dioxin recommendation tolerable daily intake				BoD	DALY/case	0.0001 - 0.0101	Goherr assessment
18	Dioxin recommendation tolerable daily intake 2018				BoD	DALY /case	0.0001 - 0.0101	Goherr assessment
19	Loss in child's IQ points				BoD	DALY/IQ	0.11 (0.06 - 0.16)	Arja used 0.013 but here we use Goherr value instead.
20	PFAS TWI				BoD	DALY/case	0.0001 - 0.0101	PFAS assessment
21	Sperm concentration	Gender:Female			BoD	DALY/case	0	Goherr assessment
22	Sperm concentration	Gender:Male			BoD	DALY/case	0 - 5	Goherr assessment
23	Vitamin D recommendation				BoD	DALY/case	0.0001 - 0.0101	Goherr assessment
24	Yes or no dental defect				BoD	DALY/case	0 - 0.12	Goherr assessment

Sources:

• WHO2017a
• Heimtsa & Intarese 2011
• Bachmann & van der Kamp 2017
• De Leeuw & Horálek 2016/5
• Holland (2014), corrected to price levels of 2015. Amounts are based on the lower limits.
• Goherr assessment
• PFAS assessment

Calculations

+ Show code- Hide code # This is code Op_en7980/case_burden on page [[Case burden]]. library(OpasnetUtils) case_burden <- Ovariable("case_burden", ddata="Op_en7980", subset="Case burdens of environmental health outcomes") objects.latest("Op_en2031", code_name="subgrouping") # [[ERF]] subgrouping case_burden@data <- subgrouping(case_burden@data)[-(2:3)] # Define subgroups and drop disability weights and durations objects.store(case_burden) cat("Ovariable case_burden saved. \n") oprint(case_burden@data)

See also

• Case burden of waterborne microbes