View source for ERF of indoor dampness on respiratory health effects

[[Category:Indoor air]]
[[Category:Dampness]]
[[Category:Exposure-response functions]]
[[Category:Health effects]]
[[Category:Mega case study]]
[[Category: CLAIH]]
[[Category:Urgenche]]
[[Category:Contains R code]]
{{variable|moderator=Ulla H-S}}

Exposure-response function of exposure to indoor dampness and/or mold or mold odor and respiratory health effects. The exposure-response function is expressed as ERF. 

== Question ==

What is the association between exposure to indoor dampness and mould in homes and respiratory health effects?

== Answer ==

'''Exposure-response function

<rcode graphics="1">
library(OpasnetUtils) # A package with Opasnet functionalities
library(xtable)       # A package with table formats
library(ggplot2)      # A package with fancy graph formats

objects.latest("Op_en4716", "calculations") # Get the latest ovariables from code calculations on page Op_en4716.

ERF		<- EvalOutput(ERF, N = 100)

ERF@output <- data.frame(ERF@output, Pollutant = "Indoor.dampness") # This is needed because the Pollutant column is missing from the data table.

print(xtable(ERF@output[ERF@output$Iter == 1 , ], digits = 4), type = 'html')

ggplot(ERF@output[ERF@output$ERF.parameter == "OR" , ], # Show a 
	aes(x = Disease, y = ERFResult)) + # , fill = Response.metric)) +
	geom_boxplot() + 
	theme_grey(base_size = 24) +
	theme(axis.text.x = element_text(angle = 90, hjust = 1))

</rcode>

== Rationale==

=== Data ===

<t2b index="Disease,Response metric,Subjects,Exposure route,Exposure metric,Exposure unit,ERF parameter,Threshold,Observation" locations="Result,Description" unit=" OR per yes/no visible dampness and/or mold or mold odor
">
Upper respiratory tract symptoms||All|Inhalation|visible dampness and/or mold or mold odor|yes/no|OR|0|1.70 (1.44-2.00)| No. studies: 13
Cough||All|Inhalation|visible dampness and/or mold or mold odor|yes/no|OR|0|1.67 (1.49-1.86)| No. studies: 18
Cough||Adults|Inhalation|visible dampness and/or mold or mold odor|yes/no|OR|0|1.52 (1.18-1.96)| No. studies: 6
Cough||Children|Inhalation|visible dampness and/or mold or mold odor|yes/no|OR|0|1.75 (1.56-1.96)| No. studies: 6
Wheeze||All|Inhalation|visible dampness and/or mold or mold odor|yes/no|OR|0|1.50 (1.38-1.64)| No. studies: 22
Wheeze||Adults|Inhalation|visible dampness and/or mold or mold odor|yes/no|OR|0|1.39 (1.04-1.85)| No. studies: 5
Wheeze||Children|Inhalation|visible dampness and/or mold or mold odor|yes/no|OR|0|1.53 (1.39-1.68)| No. studies: 17
Current asthma||All|Inhalation|visible dampness and/or mold or mold odor|yes/no|OR|0|1.56 (1.30-1.86)| No. studies: 10
Ever-diagnosed asthma||All|Inhalation|visible dampness and/or mold or mold odor|yes/no|OR|0|1.37 (1.23-1.53)| No. studies: 8
Ever-diagnosed asthma||Children|Inhalation|visible dampness and/or mold or mold odor|yes/no|OR|0|1.35 (1.20-1.51)| No. studies: -
Asthma development||All|Inhalation|visible dampness and/or mold or mold odor|yes/no|OR|0|1.34 (0.86-2.10)| No. studies: 4
Bronchitis||All|Inhalation|visible dampness and/or mold or mold odor|yes/no|OR|0|1.45 (1.32-1.59)| No. studies: -
Bronchitis||Children|Inhalation|visible dampness and/or mold or mold odor|yes/no|OR|0|1.38 (1.28-1.47)| No. studies: -
Respiratory infections||All|Inhalation|visible dampness and/or mold or mold odor|yes/no|OR|0|1.44 (1.31-1.59)| No. studies: -
Respiratory infections||Adults|Inhalation|visible dampness and/or mold or mold odor|yes/no|OR|0|1.49 (1.14-1.95)| No. studies: -
Respiratory infections||Children|Inhalation|visible dampness and/or mold or mold odor|yes/no|OR|0|1.48 (1.33-1.65)| No. studies: -
Sensitivity to inhaled antigens||Children|Inhalation|visible dampness and/or mold or mold odor|yes/no|OR|0|1.33 (1.23-1.44)| No. studies: -
Hay fever||Children|Inhalation|visible dampness and/or mold or mold odor|yes/no|OR|0|1.35 (1.18-1.53)| No. studies: -
</t2b>

<ref>W. J. Fisk, Q. Lei-Gomez, M. J. Mendell. Meta-analyses of the associations of respiratory health e?ects with dampness and mold in homes. Indoor Air 2007; 17: 284–296. {{doi|10.1111/j.1600-0668.2007.00475.x}}</ref> <ref>[http://ehp03.niehs.nih.gov/article/fetchArticle.action?articleURI=info%3Adoi%2F10.1289%2Fehp.1002410 Mendell et al. 2011. Respiratory and allergic health effects of dampness and mold, and dampness-related agents: a review of the epidemiological evidence. Environmental Health Perspectives 119(6), 748-756.]</ref>

Page-specific entries (indices that have exactly one value each for the whole variable; usually mentioned in the title and/or in the scope.):
* Pollutant: visible dampness and/or mold or mold odor
* Threshold: 0
* Exposure metric: yes/no
* Exposure route: Inhalation

===Unit===

[[OR]] for yes vs. no visible dampness and/or mold or mold odor

=== Calculations ===

<rcode label="Initiate variable" name="calculations">
library(OpasnetUtils)
library(xtable)

ERF <- Ovariable("ERF", ddata = "Op_en4716", getddata = FALSE, save = TRUE) 

cat("Ovariable ERF saved for later use. Page name: Op_en4716, code name: calculations\n")

print(xtable(EvalOutput(ERF, N = 1)@output), type = "html")

</rcode>

==See also==

* [[:heande:Moisture damage]]
* [[Assessment of building policies' effect on dampness and asthma in Europe]]

==Keywords==

Dampness and mould, ERF, Respiratory Disease, Asthma, Indoor Environment, Allergy

==References==

<references/>

==Related files==

{{mfiles}}