Impact calculation tool

This page is a knowledge crystal of subtype assessment. The page identifier is Op_en2909
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Impact Calculation Tool ICT is a tool for calculating Years of Life Lost (YLL) and Years of Life lived with a Disease (YLD). By combining these two, the model calculates a burden of disease (BoD) estimate expressed in disability adjusted lifeyears (DALY).

The tool utilizes life table approach, i.e age specific information on diseases in a given population; input data is given in 5-year categories and the model divides them evenly for the 1-year time-step used internally. ICT tool is programmed on Analytica Monte-Carlo software (Lumina, Inc., see http://www.lumina.com/). 

The model inputs include:

• Cause of death due to exposure
• Endpoints of morbidity
• Population data with 5-year age intervals
• Baseline mortality
• Baseline morbidity
• Exposure measure
• Mortality exposure-response function
• Morbidity exposure-response function
• Duration of disease
• Severity weights

Existing data on burden of disease can be used in the model with attributable fraction estimates.