PM2.5 exposure-response function

This page is a knowledge crystal of subtype variable. The page identifier is Op_en2790
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Scope

The variable describes the relationship between cardiopulomnary mortality and personal exposure to PM2.5. The personal exposure is the time-weighted average concentration of individuals given knowledge on activity patterns and concentration in diffferent microenvironments D↷

Definition

Data

• Concentration-response to PM2.5
• Studies that relate personal exposures to cardiopulmonary mortality
• Studies that relate personal exposures to intermediate health markers and studies on relationship between intermediary health impacts and cardiopulmonay mortality.
• Studies relating personal exposure to ambient concentrations and/or simulations of personal exposures given activity patterns and ambient concentrations

Causality

no parent variables

Unit

m3/ug

Formula

• Transform ambient concentration to a personal exposure measure in the Pope and Dockery studies, and derive exposure-response function (which becomes our prior)
• Simulate exposure-response function from combination of exposure-intermediary health and intermiediary health - cardiopulmonary mortality studies (gives us additional information on exposure -response )
• Update with Bayesian rule concentration-response function with above function and with additional knowledge from other existing studies on personal exposure - cardiopulmonary mortality if/when such studies exist