ERFs of environmental pollutants
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- This page contains exposure-response functions of several environmental pollutants that do not have own pages. This page used to contain e.g. estimates for dioxins, but they were moved to ERF of dioxin.
Question
What are the exposure-response functions (ERF) of environmental pollutants that do not have own pages in Opasnet?
Answer
Exposure-response function (ERF) is a mathematical quantitative description of the relationship between an exposure to an agent and the health responses it causes in the human body. How to actually estimate the responses based on ERF is described in detail on page Health impact assessment. Relevant example results can be found from here (in Finnish).
Rationale
Data
Obs | Exposure agent | Response | Age | Exposure | ER function | Scaling | Exposure unit | Threshold | ERF | Description |
---|---|---|---|---|---|---|---|---|---|---|
1 | Indoor radon | Lung cancer morbidity | Annual average indoor air concentration | RR | None | Bq /m3 | 0 | 1.0016 (1.0005-1.0031) | ||
2 | PM2.5 | Lung cancer mortality | Annual average outdoor air concentration | RR | None | µg /m3 | 0 | 1.014 (1.004-1.023) | Outdoor air, Pope et al. 2002 | |
3 | PM2.5 | Cardiopulmonary mortality | Annual average outdoor concentration | RR | None | µg /m3 | 0 | 1.009 (1.003-1.016) | Outdoor air, Pope et al. 2002 | |
4 | PM2.5 | Total mortality | Annual average outdoor air concentration | RR | None | µg /m3 | 0 | 1.0062 (1.0014-1.011) | Outdoor air | |
5 | Chlorination byproducts | Bladder cancer morbidity | Concentration in ingested water | RR | None | µg /l | 0 | 1.0039 (1.00053-1.00722) | ||
6 | Chlorination byproducts | Bladder cancer morbidity | Concentration in ingested water | RR | None | netrev /l | 0 | 1.000029 (1-1.000072) | ||
7 | Arsenic | Bladder cancer morbidity | Concentration in ingested water | RR | None | µg /l | 0 | 1.002 (0.999-1.006) | ||
8 | Formaldehyde | Asthma morbidity | <14 | Annual average indoor concentration | RR | None | µg /m3 | 0 | 1.0140743178 | |
9 | Formaldehyde | Asthma morbidity | >=14 | Annual average indoor concentration | RR | None | µg /m3 | 0 | 1 | |
10 | Dampness damage | Asthma morbidity | Yes/no moisture damage | RR | None | % | 0 | 1.37 (1.23-1.53) | ||
11 | Dampness damage | Lower respiratory symptoms morbidity | Yes/no moisture damage | RR | None | % | 0 | 1.5 (1.38-1.86) | ||
12 | Dampness damage | Upper respiratory symptoms morbidity | Yes/no moisture damage | RR | None | % | 0 | 1.7 (1.44-2) | ||
13 | Fluoride | Fluorosis | <14 | Concentration in ingested water | UR | None | 0 | 0.125 | ||
14 | Fluoride | Fluorosis | >=14 | Concentration in ingested water | UR | None | 0 | 0 | ||
15 | Outdoor ozone | Total mortality | Annual average outdoor air concentration | RR | None | µg /m3 | 0 | 1.000299596 (1.000099955-1.000399282) | ||
16 | Lead | Decrease of IQ below 70 points | Intake level from food | UR | None | ? | 0 | 0.025 | ||
17 | Lead | Increased blood pressure | Intake level from food | UR | None | ? | 0 | 0.025 | ||
18 | Formaldehyde | Nasal cancer morbidity | Annual average indoor concentration | UR | None | µg /m3 | 0 | 0.000013 | ||
19 | Benzene | Leukemia morbidity | Annual average indoor concentration | UR | None | µg /m3 | 0 | 0.000005 | ||
20 | Quatzdust | Silicosis morbidity | Indoor air concentration | UR | None | mg /m3 | 0 | 0.125; 0.125; 0.25 | ||
21 | Asbestos at work | Lung cancer and mesothelioma morbidity | Indoor air concentration | UR | None | 0 | 0.05 (0.01-0.1) | |||
22 | Noise at work | Hearing damage | Noise level | UR | None | 0 | 570 | Medium noise (80-85 dB) | ||
23 | Noise at work | Hearing damage | Noise level | UR | None | 0 | 1320 | Loud noise (>85 dB) | ||
24 | Outdoor ozone | Mild decreasing on general functioning | Annual average outdoor air concentration | UR | None | µg /m3 | 0 | 0.115 (0.044-0.186) |
Seturi ERFs
Altiste | Altisteen mittasuure ja yksikkö | Vaikutus | Tausta- tai kynnys-altistus[2] | RR (per altistusyksikkö) | Kuvaus |
---|---|---|---|---|---|
Radon | Bq/m3 | keuhko syöpä ilmaantuvuus ja kuolleisuus | 5[3] | 1.0016 | |
PM2.5 ulkoilma | µg/m3 | kuolleisuus | 2 | 1.0062 | |
Kloorauksen sivutuotteet | net rev/L | Virtsarakon syöpä ilmaantuvuus ja kuolleisuus | 0 | 1.00003[4] | |
Ulkomelu | Lden (dB) | sydäninfarkti ilmaantuvuus ja kuolleisuus | 59[5] | NA | |
Kiusallisuus/häiritsevyys | |||||
Unihäiriö | |||||
Arseeni | ug/l | Virtsarakon syöpä ilmaantuvuus ja kuolleisuus | 0.14 | 1.002 | |
ETS | Kyllä/ei | keuhko syöpä ilmaantuvuus ja kuolleisuus | 0 | 1.21 | |
ETS | IHD ilmaantuvuus ja kuolleisuus | 0 | 1.27 | ||
ETS | Astma ilmaantuvuus ja kuolleisuus | 0 | 1.97 | ||
ETS | Astma ilmaantuvuus ja kuolleisuus | 0 | 1.32 | ||
ETS | Keuhkoinfektiot | 0 | 1.55 | ||
ETS | Välikorvan tulehdus | 0 | 1.38 | ||
Formaldehydi | µg m-3 | Astma ilmaantuvuus ja kuolleisuus | 40 | 1.014 | |
Kosteusvauriot | Kyllä/ei | Astma ilmaantuvuus ja kuolleisuus | 0 | 1.37[6] | |
Alahengitystieoireet ilmaantuvuus ja kuolleisuus | 0 | 1.5[7] | |||
Ylähengitystieoireet ilmaantuvuus ja kuolleisuus | 0 | 1.7[8] | |||
Otsoni | µg/m3 | kokonaiskuolleisuus | 70[9] | 1.0003 | |
Auringon UV-säteily | Ihosyöpä | ||||
CO | Kuolleisuus | ||||
Ruoan mikrobit | Ripuli | ||||
Veden mikrobit | Ripuli | ||||
Kalan metyylielohopea | Lievä kehitysvamma vastasyntyneellä | ||||
Ympäristön lyijy | Lievä kehitysvamma | ||||
Verenpainetauti | |||||
Juomaveden fluoridi | Hampaiden fluoroosi | ||||
PM2.5 ulkoilma | µg/m3 | Krooninen bronkiitti | 2 | 5.33E-05 | |
µg/m3 | Vakava oirepäivä | 2 | 0.0902 | ||
Itämeren kalan dioksiini | Syöpä | 0 | 4.6E-07[10] | ||
Luonnon radionuklidit porakaivovedessä | Sv | Syöpäkuolema | 0.0009[11] | 0.0007[12] | |
Tshernobyl laskeuma ja ydinasekokeet | Sv | Syöpäkuolema | 0.0007[13] | ||
Hengitysilman bentseeni | Leukemia | 0 | 7.14286E-08 | ||
Otsoni | µg/m3 | Oirepäivä | |||
Yskäpäivä | |||||
Alahengitystie oirepäivä |
See also
- ----#: . Check some translations (chlorinating, surrounding's tobacco smoke, fluorosis, dampness damage,Nose-pharynx cancers, Mild decreasing on general funtioning) --Heta 18:43, 12 October 2012 (EEST) (type: truth; paradigms: science: comment)
- ----#: . Note that ERFs for "Environmental tobacco smoke" were moved to Indoor environment quality (IEQ) factors page, where they belong to. --Marjo 13:56, 28 March 2013 (EET) (type: truth; paradigms: science: comment)
- op_fi:Seturi (in Finnish)
- op fi:Seturi/Annosvaste
Generic variable
This variable is included in Exposure-response function.
References
- ↑ Tekaisu-hankkeen työpaketti 2. N:\YMAL\Projects\Tekaisu\TP2\BoD methodology\Seturi_DALY_simple_GHE2012_päivitys.xlsx versio 17.11.2016.
- ↑ Either natural background or if the dose-response slope does not go to zero
- ↑ Ulkoilman Rn pitoisuus
- ↑ Koivusalo et al. 1998
- ↑ Ei varsinainen kynnysaltistus, mutta altistusvastekäyrä leikkaa x-akselin noin kohdassa Lden = 59 dB, eli riski alkaa kohota vasta tässä kohden. Ref. Babisch, 2008.
- ↑ Lääkärin diagnosoima astma: best guess = OR 1.37, Min = OR 1.23, Max = OR 1.53. Astman puhkeaminen: Best guess = OR 1.34, Min = OR 0.86, Max = OR 2.10. Fisk et al. 2007.
- ↑ Best guess = OR 1.50, Min = OR 1.38, Max = OR 1.86. Fisk et al. 2007.
- ↑ Best guess = OR 1.70, Min = OR 1.44, Max = OR 2.00. Fisk et al. 2007.
- ↑ SOMO35-altistusmittari on jo vähentänyt kynnysrajan allapuolisen altistuksen tämä tässä vain tiedoksi.
- ↑ Fatty fish PCDD/F Teq * csf * unit conversion,where Fatty fish PCDD/F Teq is toxicity (in Teq's) of dioxin congeners found typically in fatty fish, such as salmon; csf is cancer slope factor [mg/kg/day]^-1 for TCDD (Teq=1); unit conversion relates to conversion from mg -> pg [1].
- ↑ vesilaitosvedestä saatava annos
- ↑ ICRP 103: based on cancer incidence data, detriment adusted nominal risk coefficients for cancer for whole population = 5,5%/Sv; 5% increase in lifetime cancer deaths/Sv. Muutettu Päivin 25.9. mailin mukaisesti 0.05
- ↑ ICRP 103: based on cancer incidence data, detriment adusted nominal risk coefficients for cancer for whole population = 5,5%/Sv; 5% increase in lifetime cancer deaths/Sv. Muutettu Päivin 25.9. mailin mukaisesti 0.05