ERFs of vitamins

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Question

What are exposure-response functions to vitamins?

Rationale

Data

ERFs of vitamins(-)

Obs	Exposure agent	Trait	Response metric	Exposure route	Exposure metric	Exposure unit	ERF parameter	Scaling	Threshold	ERF	Description
1	Vitamin D	Vitamin D recommendation	1 if recommendation not met	Ingestion	Daily intake	ug /d	Step	None	7.5	100

Calculations

+ Show code- Hide code library(OpasnetUtils) d <- opbase.data("Op_en6866") d$Obs <- NULL colnames(d) <- gsub(" ", "_", colnames(d)) d$Exposure_agent <- gsub(" ", "_", d$Exposure_agent) d$Result <- ifelse(d$Result == "", "0", as.character(d$Result)) ERF <- Ovariable("ERF", data = d[d$Observation == "ERF", colnames(d) != "Observation"]) threshold <- Ovariable("Threshold", data = d[d$Observation == "Threshold", colnames(d) != "Observation"]) objects.store(ERF, threshold) cat("Ovariables ERF, threshold stored.\n")

References

• Serum 25-hydroxyvitamin D levels and survival in colorectal and breast cancer patients: Systematic review and meta-analysis of prospective cohort studies
• New insights into the role of vitamin D and calcium in osteoporosis management: an expert roundtable discussion.
• Vitamin D Therapy
• Vitamin D insufficiency and chronic diseases: hype and reality.
• Osteoporosis - a review
• Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety.
• Low vitamin D status: definition, prevalence, consequences, and correction.