ERF of dioxin

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Scope

ERF of dioxin on cancer describes the quantitative relationship between exposure to polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs) and remaining lifetime cancer risk in adult Beneris population.

Definition

ERF of dioxin on cancer is indexed by variable age. It applies to the last two age categories, i.e. 18-55yr and 55yr+ (gender combined).

Data

The U.S. Environmental Protection Agency (US EPA) calculated an oral cancer slope factor (CSF) for 2,3,7,8 - TCDD (the most toxic dioxin compound). This CFS equals to 156000 (mg/kg bw-d)^-1 and represents the upper 95^th percentile estimate of the probability of developing cancer per unit intake of chemical over a lifetime. 

Unit

(mg/kg bw/d)^-1

Result

156000