Narcolepsy in Finland

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Scope

What is the prevalence and incidence of narcolepsy (ICD-10 G47.4) in Finland?

Definition

Literature

• In general the prevalence of narcolepsy is bout 0.05% in the world population.
  • In Finland it is slightly smaller at 0.026%.
• Narcolepsy is "very rare" in subjects younger than 10 years old.
• General incidence is about 1.4*10^-5a^-1.
  • In about 10% of cases evidence of affected relatives exists.
• In twin studies the environment has been shown to have a very large impact.
• Symptoms "seem to" peak at ages 15 and 36.
• Suspected triggers: infections, allergic reactions, inflammatory diseases, other autoimmunity diseases, brain damage, thyroid disorders, psychological trauma

Data

• Diagnosis definition was updated in 2005.
  • Comparison to earlier years not consistent.
• Data for 2006-2009 originates from THL treatment registry (reports of diagnosed ICD-10 G47.4).
  • Data for 2010 was gathered from health care municipalities and private sleep-clinics by the narcolepsy work group

Narcolepsy cases (incidence) by age group for 2006-2010

Narcolepsy in Finland(#)

Obs	Age group	2006	2007	2008	2009	2010
1	0-4	0	0	0	1	0
2	5-9	0	1	0	0	18
3	10-14	2	1	5	3	29
4	15-19	3	4	9	6	11
5	20-24	3	10	6	14	3
6	25-29	2	8	4	7	7
7	30-34	5	5	4	8	2
8	35-39	1	3	6	5	4
9	40-44	6	3	3	3	4
10	45-49	4	6	3	4	4
11	50-54	2	4	3	3	0
12	55-59	3	6	4	3	3
13	60-64	3	4	6	1	5
14	65-69	3	2	4	3	2
15	70-74	3	1	1	3	2
16	75-79	2	1	2	2	0
17	80-	2	0	0	2	0
18	Total	44	59	60	68	102

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