Chlamydia pneumoniae Infection Among Healthy Children and Children Hospitalised with Pneumonia in Greece

Scope

Chlamydia pneumoniae Infection Among Healthy Children and Children Hospitalised with Pneumonia in Greece

Definition

Chlamydia pneumoniae has been recognized as a cause of respiratory tract infection in humans, and its prevalence has been shown to vary among different age groups and populations. The prevalence of Chlamydia pneumoniae antibody was determined by serological investigation in 343 healthy children and in 77 children consecutively hospitalised for pneumonia in southwestern Greece.

Result

Seventy-eight (22.7%) healthy children had IgG Chlamydia pneumoniae titers ≥1/8. The prevalence of Chlamydia pneumoniae antibody in the age groups 6 months–5 years, 6–9 years and 10–15 years was 7.9%, 11.4% and 36%, respectively. One child hospitalised for pneumonia had serological results consistent with acute Chlamydia pneumoniae infection.

Conclusion

The results of the present study suggest a low prevalence of Chlamydia pneumoniae antibody among preschoolers in Greece, followed by a steep rise in children 10–15 years of age. Chlamydia pneumoniae is not a common etiologic agent of childhood pneumonia requiring hospitalisation.

Acknowledgements

Study summary from: Swatee P Patel, Marjo-Riitta Järvelin and Mark P Little. Systematic review of worldwide variations of the prevalence of wheezing symptoms in children. Environmental Health 2008, 7:57.