Impact calculation tool

This page is a knowledge crystal of subtype assessment. The page identifier is Op_en2909
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Impact Calculation Tool ICT is a tool for calculating Years of Life Lost (YLL) and Years of Life lived with a Disease (YLD). By combining these two, the model calculates a burden of disease (BoD) estimate expressed in disability adjusted lifeyears (DALY).

The tool utilizes life table approach, i.e age specific information on diseases in a given population; input data is given in 5-year categories and the model divides them evenly for the 1-year time-step used internally. ICT tool is programmed on Analytica Monte-Carlo software (Lumina, Inc., see http://www.lumina.com/). 

The model inputs include:

• Cause of death due to exposure
• Endpoints of morbidity
• Population data with 5-year age intervals
• Baseline mortality
• Baseline morbidity
• Exposure measure
• Mortality exposure-response function
• Morbidity exposure-response function
• Duration of disease
• Severity weights

Existing data on burden of disease can be used in the model with attributable fraction estimates.

Future develoment work with the tool contains comparative use of common currencies other than DALY (e.g. $, QALY, deahts before certain age) and features to include databases within the model, and an advanced user interface.