Case burden of waterborne microbes

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Scope

What are the case burdens (in DALYs) of waterborne microbes?

Answer

The case burdens are presented as DALYs per infected individual. These include both those who get ill with the disease as well as those carrying the pathogen.

Case burdens of waterborne microbes(DALY)
ObsDiseaseSubgroupResultDescription
1GiardiaAge:Age 0-40.002425060273973
2GiardiaAge:Age 5-90.002732458082192
3GiardiaAge:Age 10-140.004313122191781
4GiardiaAge:Age 15-640.002572193972603
5GiardiaAge:Age 65-810.006244547945205
6CryptosporidiumAge:Age 0-40.001768459987478
7CryptosporidiumAge:Age 5-90.002801479147212
8CryptosporidiumAge:Age 10-140.004051679355586
9CryptosporidiumAge:Age 15-640.001768450068397
10CryptosporidiumAge:Age 65-810.010969156357322
11NorovirusAge:Age 0-40.000854356334858
12NorovirusAge:Age 5-90.000527168738082
13NorovirusAge:Age 10-140.000558226165288
14NorovirusAge:Age 15-650.000550474210904
15NorovirusAge:Age 66-810.001776198506945
16RotavirusAge:Age 0-40.003431215134247
17RotavirusAge:Age 5-90.001095840616438
18RotavirusAge:Age 11-140.001120609306849
19RotavirusAge:Age 15-640.000888790216438
20RotavirusAge:Age 65-810.000990939378082

Rationale

Data

Data for Giardia used in the calculations. The probability of illness if infected is 1.

treatment age probability of needing the treatment if ill duration severity
untreated 0-4 0.9375 0.027397260273973 0.067
untreated 5-9 0.91034 0.027397260273973 0.067
untreated 10-14 0.72642 0.027397260273973 0.067
untreated 15-64 0.92486 0.027397260273973 0.067
untreated 65-81 0.5365 0.027397260273973 0.067
general practitioner 0-4 0.0609 0.027397260273973 0.393
general practitioner 5-9 0.0852 0.027397260273973 0.393
general practitioner 10-14 0.272 0.027397260273973 0.393
general practitioner 15-64 0.0721 0.027397260273973 0.393
general practitioner 65-81 0.451 0.027397260273973 0.393
hospitalised 0-4 0.0015 0.082191780821918 0.393
hospitalised 5-9 0.00446 0.082191780821918 0.393
hospitalised 10-14 0.00158 0.082191780821918 0.393
hospitalised 15-64 0.00304 0.082191780821918 0.393
hospitalised 65-81 0.0125 0.082191780821918 0.393

Data for Cryptosporidium used in the calculations. The probability of illness if infected is 0.71.

treatment age probability of needing the treatment if ill duration severity
untreated 0-4 0.917573005 0.00958904109589 0.067
untreated 5-9 0.80937 0.00958904109589 0.067
untreated 10-14 0.68105 0.00958904109589 0.067
untreated 15-64 0.9774191 0.00958904109589 0.067
untreated 65-81 0.94706 0.00958904109589 0.067
general practitioner 0-4 0.082 0.019178082191781 0.393
general practitioner 5-9 0.188 0.019178082191781 0.393
general practitioner 10-14 0.316 0.019178082191781 0.393
general practitioner 15-64 0.0209 0.019178082191781 0.393
general practitioner 65-81 0.0367 0.019178082191781 0.393
hospitalised 0-4 0.000426 0.05041095890411 0.393
hospitalised 5-9 0.00263 0.05041095890411 0.393
hospitalised 10-14 0.0029 0.05041095890411 0.393
hospitalised 15-64 0.00166 0.05041095890411 0.393
hospitalised 65-81 0.0146 0.05041095890411 0.393

Probability of death, if ill with Cryptosporidium.

age probability
0-4 9.95E-07
5-14 0
15-64 2.09E-05
65-81 0.00164

Data for norovirus used in the calculations. The probability of illness if infected is 0.7.

treatment age probability of needing the treatment if ill duration severity
untreated 0-4 0.94876706 0.01041095890411 0.067
untreated 5-9 0.9902 0.01041095890411 0.067
untreated 10-14 0.98239 0.01041095890411 0.067
untreated 15-65 0.98434 0.01041095890411 0.067
untreated 66-81 0.992741 0.01041095890411 0.067
general practitioner 0-4 0.0448 0.015698630136986 0.393
general practitioner 5-9 0.0086 0.015698630136986 0.393
general practitioner 10-14 0.0154 0.015698630136986 0.393
general practitioner 15-65 0.0137 0.015698630136986 0.393
general practitioner 66-81 0.00617 0.015698630136986 0.393
hospitalized 0-4 0.00643 0.019808219178082 0.393
hospitalized 5-9 0.0012 0.019808219178082 0.393
hospitalized 10-14 0.00221 0.019808219178082 0.393
hospitalized 15-65 0.00196 0.019808219178082 0.393
hospitalized 66-81 0.000885 0.019808219178082 0.393

Probability of death if ill with norovirus

age probability
0-4 2.94E-06
5-65 0
66-81 0.00024

The data for rotavirus used in the calculations. The probability of illness if infected is 0.9. The probability of death from being ill with rotavirus is 2.13E-05 for 0-4-year-olds and 0 for everyone else.

treatment age probability of needing the treatment if ill duration severity
untreated 0-4 0.82 0.013424657534247 0.067
untreated 5-14 0.95 0.013424657534247 0.067
untreated 15-64 0.99 0.013424657534247 0.067
untreated 65-81 0.97 0.013424657534247 0.067
general practitioner 0-4 0.137 0.019452054794521 0.393
general practitioner 5-9 0.0244 0.019452054794521 0.393
general practitioner 11-14 0.0511 0.019452054794521 0.393
general practitioner 15-64 0.0127 0.019452054794521 0.393
general practitioner 65-81 0.0299 0.019452054794521 0.393
hospitalized 0-4 0.0416 0.021095890410959 0.393
hospitalized 5-9 0.0213 0.021095890410959 0.393
hospitalized 10-81 0 0.021095890410959 0.393
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