Risk of dental aberrations in children in Beneris
<accesscontrol>beneris</accesscontrol>
Scope
The variable describes developmental defects in human teeth as enamel defects of all human teeth.
Definition
Causality
List of parents:
Data
Formula
Unit
Relative risk (risk %)
Result [1][2][3]
| Exposure cases | Observation n | Cases | Serum 2,4,7,8-TCDD concn. range, pg/g lipid | Serum 2,4,7,8-TCDD concn. mean, pg/g lipid | Risk % | Risk ratio |
|---|---|---|---|---|---|---|
| Control | 49 | 11 | 31-226 | 128.5 | 22 | 1 |
| Exposed | 11 | 5 | 238-592 | 415 | 45 | 2.05 |
| Exposed | 15 | 9 | 700-26000 | 3000 | 60 | 2.73 |
References
- ↑ Alaluusua, S., Calderara, P., Gerthoux, P.M., Lukinmaa, P-L., Kovero, O., Needham, L., Patterson, D.G., Tuomisto, J., and Mocarelli, P. (2004) Developmental dental aberrations after the dioxin accident in Seveso. Environ Health Perspect. 112, 1313-8.
- ↑ Kattainen, H., Tuukkanen, J., Simanainen, U., Tuomisto, J.T., Kovero, O., Lukinmaa, P-L., Alaluusua, S., Tuomisto, J., and Viluksela, M. (2001) In utero/lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure impairs molar tooth development in rats. Toxicol Appl Pharmacol. 174, 216-24.
- ↑ Niittynen, M. Tuomisto1, JT., Karjalainen, A., Pekkanen,J. A case study of combining epidemiology and toxicology in environmental health risk assessment: TCDD-induced dental aberrations in humans and rats. (manuscript in prep.)