ERF of dioxin on cancer: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
mNo edit summary |
||
| Line 1: | Line 1: | ||
== | {{Variable|Exposure-response functions}} | ||
== Scope == | |||
'''ERF of dioxin on cancer '''describes the quantitative relationship between exposure to polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs) and cancer risk in adults.<br><!--[if gte mso 10]> | '''ERF of dioxin on cancer '''describes the quantitative relationship between exposure to polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs) and cancer risk in adults.<br><!--[if gte mso 10]> | ||
| Line 26: | Line 28: | ||
ERF of dioxin on cancer is indexed by variable age. It applies to the last two age categories, i.e. 18-55yr and 55yr+. | ERF of dioxin on cancer is indexed by variable age. It applies to the last two age categories, i.e. 18-55yr and 55yr+. | ||
=== Causality | === Causality === | ||
=== Data === | === Data === | ||
| Line 34: | Line 36: | ||
=== Formula === | === Formula === | ||
=== Unit === | === Unit === | ||
| Line 42: | Line 43: | ||
== Result == | == Result == | ||
156000 | 156000 | ||
== References == | == References == | ||
<references / | <references /> | ||
Revision as of 06:25, 26 March 2009
| Moderator:Nobody (see all) Click here to sign up. |
|
|
| Upload data
|
Scope
ERF of dioxin on cancer describes the quantitative relationship between exposure to polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs) and cancer risk in adults.
Definition
ERF of dioxin on cancer is indexed by variable age. It applies to the last two age categories, i.e. 18-55yr and 55yr+.
Causality
Data
The U.S. Environmental Protection Agency (US EPA) calculated an oral cancer slope factor (CSF) for 2,3,7,8 - TCDD (the most toxic dioxin compound). This CFS equals to 156000 (mg/kg bw-d)-1 and represents the upper 95th percentile estimate of the probability of developing cancer per unit intake of chemical over a lifetime. [1]
Formula
Unit
(mg/kg bw/d)-1
Result
156000
References
- ↑ US EPA 2000. Guidance for assessing chemical contaminant data for use in fish advisories. Volume 1: Fish sampling and analysis, 3rd edition. http://www.epa.gov/waterscience/fish/advice/volume1/