Risk of dental aberrations in children in Beneris: Difference between revisions

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<accesscontrol>beneris</accesscontrol>
'''Scope'''<br>
'''Scope'''<br>
'''The variable''' describes developmental defects in human teeth as enamel defects of all human teeth.
'''The variable''' describes developmental defects in human teeth as enamel defects of all human teeth.

Revision as of 11:14, 1 November 2007

<accesscontrol>beneris</accesscontrol> Scope
The variable describes developmental defects in human teeth as enamel defects of all human teeth.

Definition

Causality

List of parents:


Data

Formula

Unit

Relative risk (risk %)

Result [1][2][3]

Exposure cases Observation n Cases Serum 2,4,7,8-TCDD concn. range, pg/g lipid Serum 2,4,7,8-TCDD concn. mean, pg/g lipid Risk % Risk ratio
Control 49 11 31-226 128.5 22 1
Exposed 11 5 238-592 415 45 2.05
Exposed 15 9 700-26000 3000 60 2.73

References

  1. Alaluusua, S., Calderara, P., Gerthoux, P.M., Lukinmaa, P-L., Kovero, O., Needham, L., Patterson, D.G., Tuomisto, J., and Mocarelli, P. (2004) Developmental dental aberrations after the dioxin accident in Seveso. Environ Health Perspect. 112, 1313-8.
  2. Kattainen, H., Tuukkanen, J., Simanainen, U., Tuomisto, J.T., Kovero, O., Lukinmaa, P-L., Alaluusua, S., Tuomisto, J., and Viluksela, M. (2001) In utero/lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure impairs molar tooth development in rats. Toxicol Appl Pharmacol. 174, 216-24.
  3. Niittynen, M. Tuomisto1, JT., Karjalainen, A., Pekkanen,J. A case study of combining epidemiology and toxicology in environmental health risk assessment: TCDD-induced dental aberrations in humans and rats. (manuscript in prep.)