Risk of dental aberrations in children in Beneris: Difference between revisions
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'''Scope'''<br> | '''Scope'''<br> | ||
'''The variable''' describes | '''The variable''' describes developmental defects in human teeth as enamel defects of all human teeth. | ||
== Definition == | == Definition == | ||
=== Causality === | === Causality === | ||
List of parents: | List of parents: | ||
* | *[[Variable:Intake of PCBs from fish]] | ||
*[[Variable:Intake of PCDD/Fs from fish]] | |||
=== Data === | === Data === | ||
=== Formula === | === Formula === | ||
=== Unit === | |||
=== | Relative risk (risk %) | ||
== Result <sup><ref>Alaluusua, S., Calderara, P., Gerthoux, P.M., Lukinmaa, P-L., Kovero, O., Needham, L., Patterson, D.G., Tuomisto, J., and Mocarelli, P. (2004) Developmental dental aberrations after the dioxin accident in Seveso. Environ Health Perspect. 112, 1313-8.</ref><ref>Kattainen, H., Tuukkanen, J., Simanainen, U., Tuomisto, J.T., Kovero, O., Lukinmaa, P-L., Alaluusua, S., Tuomisto, J., and Viluksela, M. (2001) In utero/lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure impairs molar tooth development in rats. Toxicol Appl Pharmacol. 174, 216-24.</ref><ref>Niittynen, M. Tuomisto1, JT., Karjalainen, A., Pekkanen,J. A case study of combining epidemiology and toxicology in environmental health risk assessment: TCDD-induced dental aberrations in humans and rats. (manuscript in prep.)</ref></sup>== | |||
{|{{prettytable}} | |||
! Exposure cases | |||
! Observation n | |||
! Cases | |||
! Serum 2,4,7,8-TCDD concn. range, pg/g lipid | |||
! Serum 2,4,7,8-TCDD concn. mean, pg/g lipid | |||
! Risk % | |||
! Risk ratio | |||
|----- | |||
| Control | |||
| 49 | |||
| 11 | |||
| 31-226 | |||
| 128.5 | |||
| 22 | |||
| 1 | |||
|----- | |||
| Exposed | |||
| 11 | |||
| 5 | |||
| 238-592 | |||
| 415 | |||
| 45 | |||
| 2.05 | |||
|----- | |||
| Exposed | |||
| 15 | |||
| 9 | |||
| 700-26000 | |||
| 3000 | |||
| 60 | |||
| 2.73 | |||
|} | |||
== References == | |||
<references/> | |||
Revision as of 21:08, 31 October 2007
Scope
The variable describes developmental defects in human teeth as enamel defects of all human teeth.
Definition
Causality
List of parents:
Data
Formula
Unit
Relative risk (risk %)
Result [1][2][3]
| Exposure cases | Observation n | Cases | Serum 2,4,7,8-TCDD concn. range, pg/g lipid | Serum 2,4,7,8-TCDD concn. mean, pg/g lipid | Risk % | Risk ratio |
|---|---|---|---|---|---|---|
| Control | 49 | 11 | 31-226 | 128.5 | 22 | 1 |
| Exposed | 11 | 5 | 238-592 | 415 | 45 | 2.05 |
| Exposed | 15 | 9 | 700-26000 | 3000 | 60 | 2.73 |
References
- ↑ Alaluusua, S., Calderara, P., Gerthoux, P.M., Lukinmaa, P-L., Kovero, O., Needham, L., Patterson, D.G., Tuomisto, J., and Mocarelli, P. (2004) Developmental dental aberrations after the dioxin accident in Seveso. Environ Health Perspect. 112, 1313-8.
- ↑ Kattainen, H., Tuukkanen, J., Simanainen, U., Tuomisto, J.T., Kovero, O., Lukinmaa, P-L., Alaluusua, S., Tuomisto, J., and Viluksela, M. (2001) In utero/lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure impairs molar tooth development in rats. Toxicol Appl Pharmacol. 174, 216-24.
- ↑ Niittynen, M. Tuomisto1, JT., Karjalainen, A., Pekkanen,J. A case study of combining epidemiology and toxicology in environmental health risk assessment: TCDD-induced dental aberrations in humans and rats. (manuscript in prep.)