Hämeenkyrö MSWI risk assessment: Indicators: Difference between revisions

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==== Dioxin exposure-response function on population level====
Anu T
{{var
|Name        = Dioxin exposure-response function on population level
|Focus      =
|Scope      =
|Description =
'''Dioxins''' are a group of polychlorinated dibenzo-''p''-dioxins (PCDDs) and dibenzofurans (PCDFs). 2,3,7,8-tetrachlorodibenzo-''p''-dioxin (TCDD) is the most toxic PCDD/Fs congener, and it is classified as a known human carcinogen by the International Agency for Research on Cancer (IARC).
*Health effects related to '''long-term exposure'''
**impairment of the immune system
**impairment of the developing nervous system
**impairment of the endocrine system
**impairment of reproductive functions
**increased cancer risk
Evidence concerning cancer risk is mainly from animal studies, and dioxins are probably quite weak carcinogens in humans. Evindence concerning other health effects is inconsistent.
Sensitive subgroups: foetuses, newborns, individuals with high fish consumption, individuals working in incineration plants etc. (For health effects related to '''short-term exposure''' {{Reslink|Discussion on short term effects of dioxins}})
|Inputs = Dioxin variables:
*Dioxin emissions in Hämeenkyrö
*Baseline dioxin exposure in Hämeenkyrö
*Dioxin exposure due to MSWI in Hämeenkyrö
|Index      =
|Definition  =
|Unit        = increase in lifetime risk per pg/kg body weight
|Result      = effective dose resulting in a 0.01 increase in lifetime risk of cancer mortality (ED<sub>01</sub>): 45 pg/kg body weight (95% CI 21-324 pg/kg body weight) 
tolerable daily intake (TDI): 1-4 pg/kg body weight
|References  = Crump et al. 2003. Meta-analysis of dioxin-cancer dose-response for three occupational cohorts. Environmental Health Perspectives 111 (5), 681-687.
Kogevinas 2001. Human health effects of dioxins: cancer, reproductive and endochrine system effects. Human Reproduction Update 7 (3), 331-339.
Tuomisto et al. 1999. Synopsis on dioxins and PCBs. Publications of the National Public Health Institute B17/1999.
}}
}}



Revision as of 17:58, 25 September 2006

See the main page of this assessment: Hämeenkyrö MSWI risk assessment: General

  • Decisions related to Hämeenkyrö case
  • Possible indicators (optimising variables) in Hämeenkyrö

Well-being of the population (smells, comfort, noise)

Kari Auri

Effects on economy (esp. gas energy plant)

Juha

Transportation costs of waste


Health effects of dioxins and PM2.5

Anu T