Risk assessment of nitrate in drinking water: Difference between revisions

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* Infants < 6 months of age
* Infants < 6 months of age
* Exposure to nitrate via baby food formula mixed with drinking water
* Exposure to nitrate via baby food formula mixed with drinking water
* Effects: infant methemoglobinemia. More detailed information about methemoglobinemia and other nitrate related health effects is found in [http://www.pyrkilo.fi/intarese/index.php/WP3.4_Selection_of_health_outcome_for_nitrates| INTAESE wiki].
* Effects: infant methemoglobinemia (iMetHb). More detailed information about methemoglobinemia and other nitrate related health effects is found in [http://www.pyrkilo.fi/intarese/index.php/WP3.4_Selection_of_health_outcome_for_nitrates| INTAESE wiki].


=== Scenarios ===
=== Scenarios ===
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=== Decision variables ===
=== Decision variables ===


* Water source (population using public/private water supplies)
* [[Drinking water source]] (population using public/private water supplies)


=== Indicators ===
=== Indicators ===


* Health risk estimates for infant MetHg
* [[Health risk estimates for iMetHb]]
* Excess cases of iMetHg
* [[Excess cases of iMetHb]]
* Total ingestion of nitrates in drinking water by infacts < 6 months
* [[Total ingestion of nitrates from drinking water]] by infacts < 6 months


=== Other variables ===
=== Other variables ===
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* Exposure of infants &lt; 6 months to water from private supply
* Exposure of infants &lt; 6 months to water from private supply
* Infection status of infants &lt; 6 months
* Infection status of infants &lt; 6 months
* Exposure response function for nitrate and iMetHg: Detailed discussion of this can be found in [http://www.pyrkilo.fi/intarese/index.php/WP3.4_Exposure-response:_nitrates_and_MetHb| INTARESE wiki]
*[[Exposure response function for nitrate and iMetHb]]: Detailed discussion of this can be found in [http://www.pyrkilo.fi/intarese/index.php/WP3.4_Exposure-response:_nitrates_and_MetHb| INTARESE wiki]




Revision as of 12:34, 16 June 2008

This is the main page of nitrate risk assessment conducted in INTARESE WP3.4. The analytica file can be uploaded here: File:Nitrate.ANA. Detailed information about nitrates in drinking water is found in INTARESE wiki.



Scope

Purpose

To investigate the effects of nitrate contaminated drinking water.

Boundaries

  • European countries in selected regions:
    • Finland
    • Romania
    • Spain
    • UK
  • Infants < 6 months of age
  • Exposure to nitrate via baby food formula mixed with drinking water
  • Effects: infant methemoglobinemia (iMetHb). More detailed information about methemoglobinemia and other nitrate related health effects is found in INTAESE wiki.

Scenarios

  • BAU (business-as-usual)

For the first pass it was deemed appropriate to carry out a diagnostic assessment i.e. to estimate the scale of the health impacts under present conditions, which in this case make use of 2001 as the baseline year. It was recognised that the causal diagram should be constructed in such a way that the introduction of policy scenarios is possible, since this is intended for the second pass of the assessment. The introduction of such potential policy scenarios would allow the diagnostic assessment to be transformed into a prognostic assessment i.e. a causal diagram which allows the estimation the likely consequences of different policy options, primarly as a basis for choosing between them. [1]

Intended users

Participants

  • Researchers at KTL
  • Researcher at Imperial College London
  • Researchers at London School of Hygiene & Tropical Medicine
  • Researchers at Municipal Institute of Medical Research Foundation

Definition

Causal diagram

Detailed documentation of the design, elaboration and construction of the causal diagram to be used in this assessment is given in article found in |INTARESE wiki. The final draft is presented in figure 1. The working Analytica version of the nitrate model File:Nitrate.ANA.

  • Figure 1 - Causal diagram for assessment of the impacts of exposure to nitrate due to MetHg

    Figure 1 - Causal diagram for assessment of the impacts of exposure to nitrate due to MetHg

  • Figure 2 - Analytica model of nitrate risk assessment

    Figure 2 - Analytica model of nitrate risk assessment

Decision variables

Indicators

Other variables

  • Concentration of nitrate in drinking water from public supply
  • Concentration of nitrate in drinking water from private supply
  • Exposure of infants < 6 months to water from private supply
  • Infection status of infants < 6 months
  • Exposure response function for nitrate and iMetHb: Detailed discussion of this can be found in INTARESE wiki


Modules

  • Figure 3 - Sources

    Figure 3 - Sources

  • Figure 4 - Exposure

    Figure 4 - Exposure

  • Figure 5 Dose response

    Figure 5 Dose response

  • Figure 6 - Health effects

    Figure 6 - Health effects

Analyses

Result

Results

Conclusions

References

  1. ↑ Briggs DJ. Integrated assessment for policies on environmental health. Draft. Unpublished document. 2008.
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