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==Kristiina telmii== | |||
<t2b index = "Substance,Observation type" locations = "CASRN,WOE 86 Guidelines,WOE Narrative,IRIS identifier" unit = "no unit"> | |||
Acenaphthene|83-32-9|Not Assessed under the IRIS program.||0442 | |||
Acenaphthylene| 208-96-8|D, Not classifiable as to human carcinogenicity|Based on no human data and inadequate data from animal bioassays.|0443 | |||
Acephate|30560-19-1|C, Possible human carcinogen|The classification is based on increased incidence of hepatocellular carcinomas and adenomas in female mice.|0354 | |||
Acetaldehyde|75-07-0|B2, Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals|Based on increased incidence of nasal tumors in male and female rats and laryngeal tumors in male and female hamsters after inhalation exposure.|0290 | |||
Acetochlor|34256-82-1|Not Assessed under the IRIS program.||0521 | |||
Acetone|67-64-1|NA, Not applicable. This substance was not assessed using the 1986 cancer guidelines (U.S. EPA, 1986).|In accordance with the Draft Revised Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1999) data are inadequate for an assessment of the human carcinogenic potential of acetone.|0128 | |||
Acetonitrile|75-05-8|D, Not classifiable as to human carcinogenicity|Under the Proposed Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1996), the carcinogenic potential of ACN following inhalation, oral, or dermal exposure is best characterized as "cannot be determined because the existing evidence is composed of conflicting data (e.g., some evidence is suggestive of carcinogenic effects, but other equally pertinent evidence does not confirm any concern)."|0205 | |||
Acetophenone|98-86-2|D, Not classifiable as to human carcinogenicity|Based on no human data and no animal data.|0321 | |||
Acetyl chloride|75-36-5|D, Not classifiable as to human carcinogenicity|No human data or animal data.|0518 | |||
Acifluorfen, sodium|62476-59-9|Not Assessed under the IRIS program.||0192 | |||
Acrolein|107-02-8|NA, Not applicable. This substance was not assessed using the 1986 cancer guidelines (U.S. EPA, 1986).|Under the Draft Revised Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1999), the potential carcinogenicity of acrolein cannot be determined because the existing data are inadequate for an assessment of human carcinogenic potential for either the oral or inhalation route of exposure. There are no adequate human studies of the carcinogenic potential of acrolein. Collectively, experimental studies provide inadequate evidence that acrolein causes cancer in laboratory animals.|0364 | |||
Acrylamide|79-06-1|B2, Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals|Based on inadequate human data and sufficient evidence of carcinogenicity in animals; significantly increased incidences of benign and/or malignant tumors at multiple sites in both sexes of rats, and carcinogenic effects in a series of one-year limited bioassays in mice by several routes of exposures. The classification is supported by positive genotoxicity data, adduct formation activity, and structure-activity relationships to vinyl carbamate and acrylonitrile.|0286 | |||
Acrylic acid|79-10-7|Not Assessed under the IRIS program.||0002 | |||
Acrylonitrile|107-13-1|B1, Probable human carcinogen - based on limited evidence of carcinogenicity in humans|The observation of a statistically significant increase in incidence of lung cancer in exposed workers and observation of tumors, generally astrocytomas in the brain, in studies in two rat strains exposed by various routes (drinking water, gavage, and inhalation) forms the basis for this classification.|0206 | |||
Adiponitrile|111-69-3|D, Not classifiable as to human carcinogenicity|No human and no animal cancer data were available. Adiponitrile was negative for mutagenicity in Salmonella with and without activation.|0515 | |||
Alachlor|15972-60-8|Not Assessed under the IRIS program.||0129 | |||
Alar|1596-84-5|Not Assessed under the IRIS program.||0287 | |||
Aldicarb|116-06-3|D, Not classifiable as to human carcinogenicity|Aldicarb was not found to induce statistically significant increases in tumor incidence in mice or rats in feeding studies or mice in a skin painting study. In the feeding studies there were, however, significant trends in pituitary tumors in female rats and fibrosarcomas in the male mouse. This evidence, together with the fact that less than maximum tolerated doses were used, indicates that the available assays are inadequate to assess the carcinogenic potential of aldicarb.|0003 | |||
Aldicarb sulfone|1646-88-4|Not Assessed under the IRIS program.||0312 | |||
Aldrin|309-00-2|B2, Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals|Orally administered aldrin produced significant increases in tumor responses in three different strains of mice in both males and females. Tumor induction has been observed for structurally related chemicals, including dieldrin, a metabolite.|0130 | |||
Ally|74223-64-6|Not Assessed under the IRIS program.||0288 | |||
Allyl alcohol|107-18-6|Not Assessed under the IRIS program.||0004 | |||
Allyl chloride|107-05-1|C, Possible human carcinogen|Classification is based on a low (but biologically important) incidence of forestomach tumors in female mice and positive results in a variety of genetic toxicity tests. Allyl chloride is an alkylating agent and structurally related to probable human carcinogens.|0387 | |||
Aluminum phosphide|20859-73-8|Not Assessed under the IRIS program.||0005 | |||
Amdro|67485-29-4|Not Assessed under the IRIS program.||0207 | |||
Ametryn|834-12-8|Not Assessed under the IRIS program.||0208 | |||
4-Aminopyridine|504-24-5|D, Not classifiable as to human carcinogenicity|No human data and no animal data available.|0440 | |||
Amitraz|33089-61-1|Not Assessed under the IRIS program.||0334 | |||
Ammonia|7664-41-7|Not Assessed under the IRIS program.||0422 | |||
Ammonium acetate|631-61-8|D, Not classifiable as to human carcinogenicity|No human data and no animal data|0517 | |||
Ammonium methacrylate|16325-47-6|D, Not classifiable as to human carcinogenicity|No human data and no animal data|0516 | |||
Ammonium sulfamate|7773-06-0|Not Assessed under the IRIS program.||0007 | |||
Aniline|62-53-3|B2, Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals|Induction of tumors of the spleen and the body cavity in two strains of rat, and some supporting genetic toxicological evidence.|0350 | |||
ortho-Anisidine|90-04-0|Not Assessed under the IRIS program.||0610 | |||
Anthracene|120-12-7|D, Not classifiable as to human carcinogenicity|Based on no human data and inadequate data from animal bioassays.|0434 | |||
Antimony|7440-36-0|Not Assessed under the IRIS program.||0006 | |||
Antimony trioxide|1309-64-4|Not Assessed under the IRIS program.||0676 | |||
Apollo|74115-24-5|C, Possible human carcinogen|Based on an increase in thyroid gland follicular cell tumors in male rats and supportive findings in pituitary/thyroid hormone activity.|0008 | |||
Aramite|140-57-8|B2, Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals|Based on no human data and sufficient data from animal bioassays including increased incidence of liver tumors and/or neoplastic nodules in three strains of male and female rats and males of one strain of mice, and extrahepatic biliary system tumors in dogs following chronic oral exposure.|0473 | |||
Aroclor 1016|12674-11-2|Not Assessed under the IRIS program.||0462 | |||
Aroclor 1248|12672-29-6|Not Assessed under the IRIS program.||0649 | |||
Aroclor 1254|11097-69-1|Not Assessed under the IRIS program.||0389 | |||
Arsenic, inorganic|7440-38-2|A, Human Carcinogen| Based on sufficient evidence from human data. An increased lung cancer mortality was observed in multiple human populations exposed primarily through inhalation. Also, increased mortality from multiple internal organ cancers (liver, kidney, lung, and bladder) and an increased incidence of skin cancer were observed in populations consuming drinking water high in inorganic arsenic.|0278 | |||
Arsine|7784-42-1|Not Assessed under the IRIS program.|| | |||
</t2b> | |||
Revision as of 13:02, 25 June 2012
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Static GoogleMaps test
Kuopio buildings on Google maps test
GoogleMaps Sorvi MML TEST
GoogleMaps PostgreSQL test 2
GoogleMaps PostgreSQL test
Opasnet.csv test
Opasnet.data and BUGS test
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Hello
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Bluebox
- works
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R-tools code include example
Rectangle area test
Kristiina telmii
| Obs | Substance | CASRN | WOE 86 Guidelines | WOE Narrative | IRIS identifier |
|---|---|---|---|---|---|
| 1 | Acenaphthene | 83-32-9 | Not Assessed under the IRIS program. | 0442 | |
| 2 | Acenaphthylene | 208-96-8 | D, Not classifiable as to human carcinogenicity | Based on no human data and inadequate data from animal bioassays. | 0443 |
| 3 | Acephate | 30560-19-1 | C, Possible human carcinogen | The classification is based on increased incidence of hepatocellular carcinomas and adenomas in female mice. | 0354 |
| 4 | Acetaldehyde | 75-07-0 | B2, Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals | Based on increased incidence of nasal tumors in male and female rats and laryngeal tumors in male and female hamsters after inhalation exposure. | 0290 |
| 5 | Acetochlor | 34256-82-1 | Not Assessed under the IRIS program. | 0521 | |
| 6 | Acetone | 67-64-1 | NA, Not applicable. This substance was not assessed using the 1986 cancer guidelines (U.S. EPA, 1986). | In accordance with the Draft Revised Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1999) data are inadequate for an assessment of the human carcinogenic potential of acetone. | 0128 |
| 7 | Acetonitrile | 75-05-8 | D, Not classifiable as to human carcinogenicity | Under the Proposed Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1996), the carcinogenic potential of ACN following inhalation, oral, or dermal exposure is best characterized as "cannot be determined because the existing evidence is composed of conflicting data (e.g., some evidence is suggestive of carcinogenic effects, but other equally pertinent evidence does not confirm any concern)." | 0205 |
| 8 | Acetophenone | 98-86-2 | D, Not classifiable as to human carcinogenicity | Based on no human data and no animal data. | 0321 |
| 9 | Acetyl chloride | 75-36-5 | D, Not classifiable as to human carcinogenicity | No human data or animal data. | 0518 |
| 10 | Acifluorfen, sodium | 62476-59-9 | Not Assessed under the IRIS program. | 0192 | |
| 11 | Acrolein | 107-02-8 | NA, Not applicable. This substance was not assessed using the 1986 cancer guidelines (U.S. EPA, 1986). | Under the Draft Revised Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1999), the potential carcinogenicity of acrolein cannot be determined because the existing data are inadequate for an assessment of human carcinogenic potential for either the oral or inhalation route of exposure. There are no adequate human studies of the carcinogenic potential of acrolein. Collectively, experimental studies provide inadequate evidence that acrolein causes cancer in laboratory animals. | 0364 |
| 12 | Acrylamide | 79-06-1 | B2, Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals | Based on inadequate human data and sufficient evidence of carcinogenicity in animals; significantly increased incidences of benign and/or malignant tumors at multiple sites in both sexes of rats, and carcinogenic effects in a series of one-year limited bioassays in mice by several routes of exposures. The classification is supported by positive genotoxicity data, adduct formation activity, and structure-activity relationships to vinyl carbamate and acrylonitrile. | 0286 |
| 13 | Acrylic acid | 79-10-7 | Not Assessed under the IRIS program. | 0002 | |
| 14 | Acrylonitrile | 107-13-1 | B1, Probable human carcinogen - based on limited evidence of carcinogenicity in humans | The observation of a statistically significant increase in incidence of lung cancer in exposed workers and observation of tumors, generally astrocytomas in the brain, in studies in two rat strains exposed by various routes (drinking water, gavage, and inhalation) forms the basis for this classification. | 0206 |
| 15 | Adiponitrile | 111-69-3 | D, Not classifiable as to human carcinogenicity | No human and no animal cancer data were available. Adiponitrile was negative for mutagenicity in Salmonella with and without activation. | 0515 |
| 16 | Alachlor | 15972-60-8 | Not Assessed under the IRIS program. | 0129 | |
| 17 | Alar | 1596-84-5 | Not Assessed under the IRIS program. | 0287 | |
| 18 | Aldicarb | 116-06-3 | D, Not classifiable as to human carcinogenicity | Aldicarb was not found to induce statistically significant increases in tumor incidence in mice or rats in feeding studies or mice in a skin painting study. In the feeding studies there were, however, significant trends in pituitary tumors in female rats and fibrosarcomas in the male mouse. This evidence, together with the fact that less than maximum tolerated doses were used, indicates that the available assays are inadequate to assess the carcinogenic potential of aldicarb. | 0003 |
| 19 | Aldicarb sulfone | 1646-88-4 | Not Assessed under the IRIS program. | 0312 | |
| 20 | Aldrin | 309-00-2 | B2, Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals | Orally administered aldrin produced significant increases in tumor responses in three different strains of mice in both males and females. Tumor induction has been observed for structurally related chemicals, including dieldrin, a metabolite. | 0130 |
| 21 | Ally | 74223-64-6 | Not Assessed under the IRIS program. | 0288 | |
| 22 | Allyl alcohol | 107-18-6 | Not Assessed under the IRIS program. | 0004 | |
| 23 | Allyl chloride | 107-05-1 | C, Possible human carcinogen | Classification is based on a low (but biologically important) incidence of forestomach tumors in female mice and positive results in a variety of genetic toxicity tests. Allyl chloride is an alkylating agent and structurally related to probable human carcinogens. | 0387 |
| 24 | Aluminum phosphide | 20859-73-8 | Not Assessed under the IRIS program. | 0005 | |
| 25 | Amdro | 67485-29-4 | Not Assessed under the IRIS program. | 0207 | |
| 26 | Ametryn | 834-12-8 | Not Assessed under the IRIS program. | 0208 | |
| 27 | 4-Aminopyridine | 504-24-5 | D, Not classifiable as to human carcinogenicity | No human data and no animal data available. | 0440 |
| 28 | Amitraz | 33089-61-1 | Not Assessed under the IRIS program. | 0334 | |
| 29 | Ammonia | 7664-41-7 | Not Assessed under the IRIS program. | 0422 | |
| 30 | Ammonium acetate | 631-61-8 | D, Not classifiable as to human carcinogenicity | No human data and no animal data | 0517 |
| 31 | Ammonium methacrylate | 16325-47-6 | D, Not classifiable as to human carcinogenicity | No human data and no animal data | 0516 |
| 32 | Ammonium sulfamate | 7773-06-0 | Not Assessed under the IRIS program. | 0007 | |
| 33 | Aniline | 62-53-3 | B2, Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals | Induction of tumors of the spleen and the body cavity in two strains of rat, and some supporting genetic toxicological evidence. | 0350 |
| 34 | ortho-Anisidine | 90-04-0 | Not Assessed under the IRIS program. | 0610 | |
| 35 | Anthracene | 120-12-7 | D, Not classifiable as to human carcinogenicity | Based on no human data and inadequate data from animal bioassays. | 0434 |
| 36 | Antimony | 7440-36-0 | Not Assessed under the IRIS program. | 0006 | |
| 37 | Antimony trioxide | 1309-64-4 | Not Assessed under the IRIS program. | 0676 | |
| 38 | Apollo | 74115-24-5 | C, Possible human carcinogen | Based on an increase in thyroid gland follicular cell tumors in male rats and supportive findings in pituitary/thyroid hormone activity. | 0008 |
| 39 | Aramite | 140-57-8 | B2, Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals | Based on no human data and sufficient data from animal bioassays including increased incidence of liver tumors and/or neoplastic nodules in three strains of male and female rats and males of one strain of mice, and extrahepatic biliary system tumors in dogs following chronic oral exposure. | 0473 |
| 40 | Aroclor 1016 | 12674-11-2 | Not Assessed under the IRIS program. | 0462 | |
| 41 | Aroclor 1248 | 12672-29-6 | Not Assessed under the IRIS program. | 0649 | |
| 42 | Aroclor 1254 | 11097-69-1 | Not Assessed under the IRIS program. | 0389 | |
| 43 | Arsenic, inorganic | 7440-38-2 | A, Human Carcinogen | Based on sufficient evidence from human data. An increased lung cancer mortality was observed in multiple human populations exposed primarily through inhalation. Also, increased mortality from multiple internal organ cancers (liver, kidney, lung, and bladder) and an increased incidence of skin cancer were observed in populations consuming drinking water high in inorganic arsenic. | 0278 |
| 44 | Arsine | 7784-42-1 | Not Assessed under the IRIS program. |