Hämeenkyrö MSWI risk assessment: Indicators: Difference between revisions

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|Scope      =  
|Scope      =  
|Description =  
|Description =  
'''Dioxins''' are a group of polychlorinated dibenzo-''p''-dioxins (PCDDs) and dibenzofurans (PCDFs).  
'''Dioxins''' are a group of polychlorinated dibenzo-''p''-dioxins (PCDDs) and dibenzofurans (PCDFs). 2,3,7,8-tetrachlorodibenzo-''p''-dioxin (TCDD) is the most toxic PCDD/Fs congener, and it is classified as a known human carcinogen by the International Agency for Research on Cancer (IARC).
 
2,3,7,8-tetrachlorodibenzo-''p''-dioxin (TCDD) is the most toxic PCDD/Fs congener, and it is classified as a known human  
 
carcinogen by the International Agency for Research on Cancer (IARC).


*Health effects related to '''long-term exposure'''
*Health effects related to '''long-term exposure'''
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**impairment of reproductive functions
**impairment of reproductive functions
**increased cancer risk  
**increased cancer risk  
Evidence concerning cancer risk is mainly from animal studies, and dioxins are probably quite weak carcinogens in humans.  
Evidence concerning cancer risk is mainly from animal studies, and dioxins are probably quite weak carcinogens in humans. Evindence concerning other health effects is inconsistent.  
 
Evindence concerning other health effects is inconsistent.  


Sensitive subgroups: foetuses, newborns, individuals with high fish consumption, individuals working in incineration plants  
Sensitive subgroups: foetuses, newborns, individuals with high fish consumption, individuals working in incineration plants etc. (For health effects related to '''short-term exposure''' {{Reslink|Discussion on short term effects of dioxins}})
 
etc. (For health effects related to '''short-term exposure''' {{Reslink|Discussion on short term effects of dioxins}})


|Inputs = Dioxin variables:
|Inputs = Dioxin variables:
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|Index      =  
|Index      =  
|Definition  =  
|Definition  =  
|Unit        = Dioxins: increase in lifetime risk per pg/kg body weight
|Unit        = increase in lifetime risk per pg/kg body weight
|Result      =  
|Result      = effective dose resulting in a 0.01 increase in lifetime risk of cancer mortality (ED<sub>01</sub>): 45 pg/kg body weight (95% CI 21-324 pg/kg body weight) 
Dioxins
*effective dose resulting in a 0.01 increase in lifetime risk of cancer mortality (ED<sub>01</sub>): 45 pg/kg body weight  


(95% CI 21-324 pg/kg body weight) 
tolerable daily intake (TDI): 1-4 pg/kg body weight
*tolerable daily intake (TDI): 1-4 pg/kg body weight


|References  = Crump et al. 2003. Meta-analysis of dioxin-cancer dose-response for three occupational cohorts. Environmental  
|References  = Crump et al. 2003. Meta-analysis of dioxin-cancer dose-response for three occupational cohorts. Environmental Health Perspectives 111 (5), 681-687.


Health Perspectives 111 (5), 681-687.
Kogevinas 2001. Human health effects of dioxins: cancer, reproductive and endochrine system effects. Human Reproduction Update 7 (3), 331-339.
 
Kogevinas 2001. Human health effects of dioxins: cancer, reproductive and endochrine system effects. Human Reproduction  
 
Update 7 (3), 331-339.


Tuomisto et al. 1999. Synopsis on dioxins and PCBs. Publications of the National Public Health Institute B17/1999.
Tuomisto et al. 1999. Synopsis on dioxins and PCBs. Publications of the National Public Health Institute B17/1999.
}}
}}


==== PM<sub>2.5</sub> exposure-response function on population level====
==== PM<sub>2.5</sub> exposure-response function on population level====

Revision as of 07:51, 22 September 2006

See the main page of this assessment: Hämeenkyrö MSWI risk assessment: General

  • Decisions related to Hämeenkyrö case
  • Possible indicators (optimising variables) in Hämeenkyrö

Well-being of the population (smells, comfort, noise)

Kari Auri

Effects on economy (esp. gas energy plant)

Juha

Transportation costs of waste

Anne

Dioxin exposure-response function on population level

Anu T

PM2.5 exposure-response function on population level

Health effects of dioxins and PM2.5

Anu T