Lateral chlorines: Difference between revisions
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{{encyclopedia|moderator=Henrik}} | {{encyclopedia|moderator=Henrik}}'''Lateral chlorines''': the four chlorine atoms in a [[PCDD/F]] molecule in positions 2, 3, 7, and 8. These four chlorines are required for binding to the AH receptor and toxic effects. They also stabilise the molecule against metabolism, which increases their half-life and tendency for accumulation. PCDD/Fs without lateral chlorines are rapidly metabolised, which prevents their accumulation in the food chain. | ||
[[category:Dioxin synopsis]] | [[category:Dioxin synopsis]] | ||
<ref>Jouko Tuomisto, Terttu Vartiainen and Jouni T. Tuomisto: Dioxin synopsis. Report. National Institute for Health and Welfare (THL), ISSN 1798-0089 ; 14/2011 [http://www.thl.fi/thl-client/pdfs/81322e2c-e9b6-4003-bb13-995dcd1b68cb]</ref> | |||
==References== | |||
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Lateral chlorines: the four chlorine atoms in a PCDD/F molecule in positions 2, 3, 7, and 8. These four chlorines are required for binding to the AH receptor and toxic effects. They also stabilise the molecule against metabolism, which increases their half-life and tendency for accumulation. PCDD/Fs without lateral chlorines are rapidly metabolised, which prevents their accumulation in the food chain. [1]