ERF of dioxin on cancer: Difference between revisions

From Opasnet
Jump to navigation Jump to search
mNo edit summary
(Redirected page to ERF of dioxin)
 
(2 intermediate revisions by 2 users not shown)
Line 1: Line 1:
{{Variable|Exposure-response functions}}
#REDIRECT [[ERF of dioxin]]
 
== Scope ==
 
'''ERF of dioxin on cancer '''describes the quantitative relationship between exposure to polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs) and cancer risk in adults.<br><!--[if gte mso 10]>
<style>
/* Style Definitions */
table.MsoNormalTable
{mso-style-name:"Table Normal";
mso-tstyle-rowband-size:0;
mso-tstyle-colband-size:0;
mso-style-noshow:yes;
mso-style-parent:"";
mso-padding-alt:0pt 5.4pt 0pt 5.4pt;
mso-para-margin:0pt;
mso-para-margin-bottom:.0001pt;
mso-pagination:widow-orphan;
font-size:10.0pt;
font-family:"Times New Roman";
mso-ansi-language:#0400;
mso-fareast-language:#0400;
mso-bidi-language:#0400;}
</style>
<![endif]-->
 
== Definition  ==
 
ERF of dioxin on cancer is indexed by variable age. It applies to the last two age categories, i.e. 18-55yr and 55yr+.
 
=== Causality ===
 
=== Data  ===
 
The U.S. Environmental Protection Agency (US EPA) calculated an oral cancer slope factor (CSF) for 2,3,7,8 - TCDD (the most toxic dioxin compound). This CFS equals to 156000 (mg/kg bw-d)<sup>-1</sup> and represents the upper 95<sup>th</sup> percentile estimate of the probability of developing cancer per unit intake of chemical over a lifetime.<span style="">&nbsp;<ref>US EPA 2000. Guidance for assessing chemical contaminant data for use in fish advisories. Volume 1: Fish sampling and analysis, 3rd edition. http://www.epa.gov/waterscience/fish/advice/volume1/</ref></span><span style=""></span>
 
=== Formula  ===
 
 
=== Unit  ===
 
(mg/kg bw/d)<sup>-1</sup>
 
== Result  ==
 
156000
 
== References  ==
 
<references />

Latest revision as of 06:01, 20 August 2014

Redirect to: