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| {{Variable|Exposure-response functions}}
| | #REDIRECT [[ERF of dioxin]] |
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| == Scope ==
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| '''ERF of dioxin on cancer '''describes the quantitative relationship between exposure to polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs) and remaining lifetime cancer risk in adult Beneris population.<br>
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| == Definition ==
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| ERF of dioxin on cancer is indexed by variable age. It applies to the last two age categories, i.e. 18-55yr and 55yr+ (gender combined).
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| === Causality ===
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| === Data ===
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| The U.S. Environmental Protection Agency (US EPA) calculated an oral cancer slope factor (CSF) for 2,3,7,8 - TCDD (the most toxic dioxin compound). This CFS equals to 156000 (mg/kg bw-d)<sup>-1</sup> and represents the upper 95<sup>th</sup> percentile estimate of the probability of developing cancer per unit intake of chemical over a lifetime.<span style=""> <ref>US EPA 2000. Guidance for assessing chemical contaminant data for use in fish advisories. Volume 1: Fish sampling and analysis, 3rd edition. http://www.epa.gov/waterscience/fish/advice/volume1/</ref></span><span style=""></span>
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| === Formula ===
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| === Unit ===
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| (mg/kg bw/d)<sup>-1</sup>
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| == Result ==
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| 156000
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| == References ==
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| <references />
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