Potency: Difference between revisions
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'''Potency:''' range of doses over which a chemical produces increasing responses. In a series of congeners several chemicals may have similar effects and have a similar efficiacy (see this), but different doses are needed for the same response. For instance 1 µg/kg of 2,3,7,8-TCDD may have the same effect as 10 µg/kg of 1,2,3,4,7,8-HxCDD, i.e. the former is 10-fold more potent than the latter.<ref>Jouko Tuomisto, Terttu Vartiainen and Jouni T. Tuomisto: Dioxin synopsis. Report. National Institute for Health and Welfare (THL), ISSN 1798-0089 ; 14/2011 [http://www.thl.fi/thl-client/pdfs/81322e2c-e9b6-4003-bb13-995dcd1b68cb]</ref> | |||
==References== | |||
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[[category:Dioxin synopsis]] | [[category:Dioxin synopsis]] | ||
[[op_fi:Voimakkuus]] | |||
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Potency: range of doses over which a chemical produces increasing responses. In a series of congeners several chemicals may have similar effects and have a similar efficiacy (see this), but different doses are needed for the same response. For instance 1 µg/kg of 2,3,7,8-TCDD may have the same effect as 10 µg/kg of 1,2,3,4,7,8-HxCDD, i.e. the former is 10-fold more potent than the latter.[1]