Sequence( 0, 23.99, 1/5 ) Dynamic simulation periods are specified in Time's definition. This is usually a list of numbers or labels, typically in some unit of time (days, weeks, months, etc.). Use the “Dynamic()” function in your variables to perform dynamic simulation. 2,339,108,476,224 1000 0 [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88,89,90,91,92,93,94,95,96,97,98,99,100,101,102,103,104,105,106,107,108,109,110,111,112,113,114,115,116,117,118,119,120,121,122,123,124,125,126,127,128,129,130,131,132,133,134,135,136,137,138,139,140,141,142,143,144,145,146,147,148,149,150,151,152,153,154,155,156,157,158,159,160,161,162,163,164,165,166,167,168,169,170,171,172,173,174,175,176,177,178,179,180,181,182,183,184,185,186,187,188,189,190,191,192,193,194,195,196,197,198,199,200,201,202,203,204,205,206,207,208,209,210,211,212,213,214,215,216,217,218,219,220,221,222,223,224,225,226,227,228,229,230,231,232,233,234,235,236,237,238,239,240,241,242,243,244,245,246,247,248,249,250,251,252,253,254,255,256,257,258,259,260,261,262,263,264,265,266,267,268,269,270,271,272,273,274,275,276,277,278,279,280,281,282,283,284,285,286,287,288,289,290,291,292,293,294,295,296,297,298,299,300,301,302,303,304,305,306,307,308,309,310,311,312,313,314,315,316,317,318,319,320,321,322,323,324,325,326,327,328,329,330,331,332,333,334,335,336,337,338,339,340,341,342,343,344,345,346,347,348,349,350,351,352,353,354,355,356,357,358,359,360,361,362,363,364,365,366,367,368,369,370,371,372,373,374,375,376,377,378,379,380,381,382,383,384,385,386,387,388,389,390,391,392,393,394,395,396,397,398,399,400,401,402,403,404,405,406,407,408,409,410,411,412,413,414,415,416,417,418,419,420,421,422,423,424,425,426,427,428,429,430,431,432,433,434,435,436,437,438,439,440,441,442,443,444,445,446,447,448,449,450,451,452,453,454,455,456,457,458,459,460,461,462,463,464,465,466,467,468,469,470,471,472,473,474,475,476,477,478,479,480,481,482,483,484,485,486,487,488,489,490,491,492,493,494,495,496,497,498,499,500,501,502,503,504,505,506,507,508,509,510,511,512,513,514,515,516,517,518,519,520,521,522,523,524,525,526,527,528,529,530,531,532,533,534,535,536,537,538,539,540,541,542,543,544,545,546,547,548,549,550,551,552,553,554,555,556,557,558,559,560,561,562,563,564,565,566,567,568,569,570,571,572,573,574,575,576,577,578,579,580,581,582,583,584,585,586,587,588,589,590,591,592,593,594,595,596,597,598,599,600,601,602,603,604,605,606,607,608,609,610,611,612,613,614,615,616,617,618,619,620,621,622,623,624,625,626,627,628,629,630,631,632,633,634,635,636,637,638,639,640,641,642,643,644,645,646,647,648,649,650,651,652,653,654,655,656,657,658,659,660,661,662,663,664,665,666,667,668,669,670,671,672,673,674,675,676,677,678,679,680,681,682,683,684,685,686,687,688,689,690,691,692,693,694,695,696,697,698,699,700,701,702,703,704,705,706,707,708,709,710,711,712,713,714,715,716,717,718,719,720,721,722,723,724,725,726,727,728,729,730,731,732,733,734,735,736,737,738,739,740,741,742,743,744,745,746,747,748,749,750,751,752,753,754,755,756,757,758,759,760,761,762,763,764,765,766,767,768,769,770,771,772,773,774,775,776,777,778,779,780,781,782,783,784,785,786,787,788,789,790,791,792,793,794,795,796,797,798,799,800,801,802,803,804,805,806,807,808,809,810,811,812,813,814,815,816,817,818,819,820,821,822,823,824,825,826,827,828,829,830,831,832,833,834,835,836,837,838,839,840,841,842,843,844,845,846,847,848,849,850,851,852,853,854,855,856,857,858,859,860,861,862,863,864,865,866,867,868,869,870,871,872,873,874,875,876,877,878,879,880,881,882,883,884,885,886,887,888,889,890,891,892,893,894,895,896,897,898,899,900,901,902,903,904,905,906,907,908,909,910,911,912,913,914,915,916,917,918,919,920,921,922,923,924,925,926,927,928,929,930,931,932,933,934,935,936,937,938,939,940,941,942,943,944,945,946,947,948,949,950,951,952,953,954,955,956,957,958,959,960,961,962,963,964,965,966,967,968,969,970,971,972,973,974,975,976,977,978,979,980,981,982,983,984,985,986,987,988,989,990,991,992,993,994,995,996,997,998,999,1000] 1 1 4 22 1 2 0 [0.05,0.5,0.95] 1 2 0 -1460 1 9 <a href="<a href="http://en.opasnet.org/w/Risk_assessment_of_nitrate_in_drinking_water">Wiki description</a> PM 14. jouta 2006 16:17 ktluser 1. Decta 2008 7:18 48,24 1,15,23,1056,542,17 2,102,90,476,224 Arial Narrow, 13 0,Model Op_en2343,2,2,0,1,C:\temp\Nitrate-1.ANA Copy.ANA No units Number of infants < 6 months in each country Intarese3249[Intarese3260='0-4']/8 768,152,1 48,24 2,0,-23,1441,800 2,0,-23,1440,799,0,MIDM 2,523,149,421,266,0,MIDM [0,1,1,0] No units <a href="http://www.pyrkilo.fi/intarese/index.php/Population_structure_of_each_area">Wiki description</a> Table(Intarese3260)( 287K,312K,421K,166K,3.88M,4.63M,2.88M,1.12M,3.18M,2.61M,1.85M,582K,701K,609K,154K,0,0,0) 768,64,1 48,29 1,1,1,1,1,1,0,,1, 2,0,-23,1440,799 2,0,-23,1440,799,0,MIDM 2,136,148,419,484,0,MIDM 65535,52427,65534 [Intarese3260] [Intarese3260] Background prelevance of iMetHb UNKNOWN CURRENTLY!!!!!!!!!! Lognormal( 1, , , 1 ) 608,48,1 52,28 2,0,-23,1280,952 2,0,-23,1281,953,1,PDFP 52425,39321,65535 [1,0,0,0] [Variable Excess_cases_of_ime2] <a href="http://www.pyrkilo.fi/intarese/index.php/Index:Age_categories">Wiki description</a> ['0-4','5-9','10-14','15-19','20-24','25-29','30-34','35-39','40-44','45-49','50-54','55-59','60-64','65-69','70-74','75-79','80-84','>85'] 768,104,1 48,12 1,1,1,1,1,1,0,,1, 2,749,102,426,516 [] ['0-4','5-9','10-14','15-19','20-24','25-29','30-34','35-39','40-44','45-49','50-54','55-59','60-64','65-69','70-74','75-79','80-84','>85'] % Percentage of bottle fed infants <6 months in Finland (2005) Imeväisikäisten ruokinta Suomessa vuonna 2005 Kaija Hasunen, Sanna Ryynänen Selvityksiä 2005:19 ISBN 952-00-1800-X (PDF), 952-00-1799-2 (nid.), ISSN 1236-2115 Triangular( 0.48, 0.51, 0.73 ) 608,112,1 52,28 2,0,-23,1280,952 2,0,-23,1281,953,1,PDFP 52425,39321,65535 [1,0,0,0] [Variable Excess_cases_of_ime2] No units <a href="http://en.opasnet.org/w/Excess_cases_of_iMetHb_in_England_and_Wales">Wiki description</a> Excess_rate_of_imet1*Infants__6_months*Background_prelevanc/100000*Percentage_of_bottle 768,240,1 48,40 1,1,1,1,1,1,0,,1, 2,102,90,476,224 2,40,50,793,499,1,STAT {!40000|Att_contlinestyle Graph_pdf_valdim:6} {!40000|Att_graphvaluerange Graph_pdf_valdim:1,0,1,1,0} Probindex:[0.5 ] [Op_en2672,Op_en2672,2,1] [Index Intarese3260, Index Op_en2672] [1,0,0,0] [Sys_localindex('STATISTICS'),1,Areas_in_england_and,1] No units (exp(Op_en2404*Op_en2403)-1) 448,240,1 48,31 2,0,-23,1441,800 2,0,-23,1440,799,0,MIDM 2,40,50,581,368,1,MIDM [] [] [1,0,0,0] [Scenarios,1,Water_companies,1,Sys_localindex('STEP'),1] These variables defined using author judgement 608,104,-1 72,96 1,0,0,1,0,1,0,,0, mg/l Concentration of NO3- in drinking water in UK (2001). <a href="http://en.opasnet.org/w/Nitrate_concentration_in_drinking_water">Wiki description</a> Table(Op_en2672)( LogNormal (18.9,,, 2.34),LogNormal(26.25,,, 2.34),LogNormal (16.35,,,10.9),LogNormal (38.85,,,0.9),LogNormal (34.071,,,0.001),LogNormal (3.0007,,,5.009),LogNormal (25.539,,,10.2),LogNormal(20.4655,,,9.231),LogNormal (28.45,,,6.862),LogNormal(5.43,,,0.8788),LogNormal(18.7,,,8.223),LogNormal (3.9753,,,595),LogNormal(2.865,,,5.777),LogNormal(28.891,,,3.782),LogNormal (16.828,,,1.11),LogNormal (18.75,,,0.22),LogNormal(19.56125,,,9.113),LogNormal (30.03,,,8.132),LogNormal (4.8454,,,8.516),LogNormal (6.167,,, .03),LogNormal(27.835,,,5.515),LogNormal (28,,,6.615),LogNormal (21.243,,,11.88),LogNormal (4.80565,,,3.023),LogNormal (6.2882,,,12.02)) 64,240,1 48,38 1,1,1,1,1,1,0,,1, 2,0,-23,1440,799 2,774,46,355,505,0,MIDM 2,-50,24,1440,799,1,PDFP 65535,52427,65534 {!40000|Att_graphvaluerange Graph_pdf_valdim:1,0,0,1,,,,0,20} {!40000|Att_graphvaluerange Op_en2401:1,,0,,0,0,,0,60} {!40000|Att_contlinestyle Graph_pdf_valdim:6} [Op_en2672] [Op_en2672,Op_en2672,Undefined,Undefined,1] [] [1,0,0,0] [Variable Excess_cases_of_ime2] [2,1,4,4,4,0] <a href="http://en.opasnet.org/w/Water_companies_in_England_and_Wales">Wiki description</a> ['ang','bou','brw','caw','cho','dcc','eas','ess','fol','har','mik','nor','nww','por','sea','sev','sos','sou','sww','teh','tha','thr','wes','wrx','yor'] 64,296,1 48,20 1,1,1,1,1,1,0,,1, 2,0,-23,1433,792 ['ang','bou','brw','caw','cho','dcc','eas','ess','fol','har','mik','nor','nww','por','sea','sev','sos','sou','sww','teh','tha','thr','wes','wrx','yor'] mg/kg/d <a href="http://en.opasnet.org/w/Total_ingestion_of_nitrates_from_drinking_water">Wiki description</a> Op_en2401*Total_daily_consump/ Weight 216,240,1 68,40 1,1,1,1,1,1,0,,1, 2,641,140,593,590 2,0,-23,1440,799,0,MIDM 2,0,-23,1440,799,1,MIDM {!40000|Graph_keylabelcolor:0,0,0} {!40000|Graph_keytextcolor:0,0,0} {!40000|Graph_axislabelcolor:0,0,0} {!40000|Graph_axistitlecolor:0,0,0} {!40000|Graph_pagebrush:65280,65280,65280} {!40000|Att_catlinestyle Graph_primary_valdim:9} [] [] 1,,,,,,10 [Water_source,1,Age_group,1,Country,1,Data,1] [Data,1,Country,1,Water_source,1] l/day Lognormal( , , 0.240, 0.800 ) 280,136,1 96,36 2,0,-23,1441,800 2,0,-23,1433,792,0,STAT 52425,39321,65535 [Variable Excess_cases_of_ime2] http://rais.ornl.gov/homepage/DRAFT_EXPOSURE_HANDBOOK.pdf kg Distribution of weight for infants < 6 months of age Lognormal( , , 5, 2 ) 128,136,1 48,24 2,0,-23,1441,800 2,392,402,416,303,1,PDFP 65535,52427,65534 [1,0,0,0] [Variable Excess_cases_of_ime2] mg/kg/d <a href="http://en.opasnet.org/w/Exposure_response_function_for_nitrate_and_iMetHb">Wiki description</a> Nitrate toxicity value for infants U.S. EPA has evaluated the noncancer oral data for nitrate and derived a reference dose (RfD) of 1.6 mg/kg-day with 10 % of risk to MetHb. 0.065850 448,136,1 68,38 1,1,1,1,1,1,0,,1, 2,538,205,764,590 2,0,-23,1440,799,0,MIDM 2,0,-23,1440,799,1,MIDM 65535,52427,65534 [] [] [Variable Excess_cases_of_ime2] ProbBands(Op_en2403) 216,368,1 68,48 2,0,-23,1280,952,1,MIDM [Op_en2672,Undefined] [Sys_localindex('PROBABILITY'),2,Areas_in_england_and,1] ProbBands(Excess_rate_of_imet1) 448,368,1 48,46 2,0,-23,1281,953,1,MIDM [Op_en2672,Undefined] [Sys_localindex('PROBABILITY'),2,Areas_in_england_and,1] ProbBands(Op_en2406) 768,368,1 48,46 2,0,0,1281,953,0,MIDM [Op_en2672,Undefined] [Sys_localindex('PROBABILITY'),3,Areas_in_england_and,1] ProbBands(Op_en2401) 64,368,1 56,40 2,104,35,984,632,1,MIDM Probindex:[0.05, 0.5, 0.95 ] [Op_en2672,Undefined] [Sys_localindex('PROBABILITY'),2,Op_en2672,1] pmea 5. syyta 2008 9:59 48,24 960,72,1 48,24 1,0,1,1,1,1,0,,0, 1,690,360,553,260,17 Abs( RankCorrel( Excess_cases_of_ime2, Op_en2406 ) ) 288,96,1 48,46 1,1,1,1,1,1,0,0,0,0 2,0,-23,1440,799,1,MIDM Flip:8 [Excess_cases_of_ime2,Undefined] [Index Op_en2672] [Areas_in_england_and,-1,Excess_cases_of_ime2,1] [ Background_prelevanc, Percentage_of_bottle, Op_en2401, Total_daily_consump, Weight, Op_en2404] ['Background prelevance of iMetHb','Percentage of bottle fed infants','[NO3-] in drinking water in England and Wales','Total daily consumption of drinking water by infants < 6 months','Weight','Slope of exposure-response function for nitrate and iMetHb'] 96,96,1 48,38 1,1,1,1,1,1,0,0,0,0 [Background_prelevanc,Percentage_of_bottle,Op_en2401,Total_daily_consump,Weight,Op_en2404] These variables defined using author judgement 280,120,-1 100,56 1,0,0,1,0,1,0,,0, ktluser 10. huhta 2008 12:14 48,24 960,128,1 48,24 1,4,31,1185,552,17 {Daly_valuation}; {Concentration_of_ni 984,264,1 60,28 [Variable Background_prevalen2, Objective Total_met_hb_mortal3] [Objective Dalys_and_or_financ2] [1] 984,328,1 64,20 2,0,-23,1152,763 [Objective Attributable_burden2] 0 384,272,1 60,32 [Variable Concentration_of_ni7, Variable Removal_of_nitrates1] [Variable Total_daily_consump7] [1,Raw_water_quality1,Concentration_of_ni6,Concentration_of_ni7,Removal_of_nitrates1] 544,112,1 72,28 [Variable Total_daily_consump6] Lognormal( 1 ) 232,112,1 48,32 2,166,180,476,224 [Constant Usage_of_nitrate_fe3] [1,Usage_of_nitrate_fe3] 232,272,1 48,32 [Variable Concentration_of_ni4] [1,Daily_sales_of_bott2] 784,184,1 48,32 [Variable Total_daily_consump6, Variable Total_daily_consump7] 888,440,1 48,28 {Dbp_dalys}; {Mirobes_dalys} 1112,264,1 48,28 [Objective Attributable_burden2, Variable Daly_and_or_cost_we2] 0 1112,112,1 48,32 [Objective Dalys_and_or_financ2] 5 96,272,1 68,32 {Chlorination}; {Dose_response_of_mi; Water_treatment_meth 992,112,1 64,28 [Objective Total_met_hb_mortal3] 736,440,1 48,29 [Variable Total_daily_consump7] 0 96,112,1 68,32 0 680,184,1 40,32 chemical and microbial quality of raw water [1] 384,440,1 52,28 {Dbp_exposure_via_dr; Dbp_exposure_via_oth; Dose_response_of_dbp 544,376,1 72,24 [Variable Standard_for_nitrat3, Constant Water_treatment_met3] [Variable Concentration_of_ni4] [1,Drinking_water_legi2] 96,376,1 64,24 2,0,0,1025,668 [Variable Removal_of_nitrates1] Actions 88,48,-1 48,24 Sources 232,48,-1 48,24 Media 368,48,-1 48,24 Exposure 704,48,-1 48,24 Impacts 992,48,-1 44,24 Valuation 1104,48,-1 48,24 0 728,112,1 92,28 [Variable Concentration_of_ni5, Variable Daily_consumption_o2] 1 736,376,1 100,24 2,102,90,476,224 [Variable Concentration_of_ni4, Variable Daily_consumption_o2, Constant Population_using_pr2] [1,Total_daily_consump6,Total_daily_consump7,Proportion_of_boile2,Population_demandin2] 728,264,1 92,24 2,102,90,476,224 [Objective Total_met_hb_mortal3] {Daly_valuation}; {Dbp_health_effects} 984,184,1 64,32 [Variable Exposure_response_f1, Variable Total_ingestion_of_3] [Objective Attributable_burden2] 216,440,1 48,29 [Chance Concentration_of_ni6] none water treatment methods [1] 544,440,1 48,28 2,0,0,1025,668 [Variable Removal_of_nitrates1] This model is built for INTARESE project, WP3.4. The risk assessment behind the <a href="http://en.opasnet.org/w/Image:Nitrate.ANA">model</a> is in the <a href="http://heande.pyrkilo.fi/heande/index.php/Risk_assessment_of_nitrate_in_drinking_water">INTARESE wiki</a> This model uses 2003 data when appropriate and possible. 928,263,-1 96,95 For instructions, see <a href="http://en.opasnet.org/en-opwiki/images/8/86/Help_for_enhanced_causal_diagrams.ANA">Help module</a> 944,344,-1 60,36 <a href="http://en.opasnet.org/w/Drinking_water_source">Wiki description</a> 56,32,1 48,24 1,1,1,1,1,1,0,,1, <a href="http://en.opasnet.org/w/Health_risk_estimates_for_iMetHb">Wiki description</a> 56,88,1 48,29 1,1,1,1,1,1,0,,1,