Sequence( 0, 23.99, 1/5 ) Dynamic simulation periods are specified in Time's definition. This is usually a list of numbers or labels, typically in some unit of time (days, weeks, months, etc.). Use the “Dynamic()” function in your variables to perform dynamic simulation. 2,339,108,476,224 1000 0 [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88,89,90,91,92,93,94,95,96,97,98,99,100,101,102,103,104,105,106,107,108,109,110,111,112,113,114,115,116,117,118,119,120,121,122,123,124,125,126,127,128,129,130,131,132,133,134,135,136,137,138,139,140,141,142,143,144,145,146,147,148,149,150,151,152,153,154,155,156,157,158,159,160,161,162,163,164,165,166,167,168,169,170,171,172,173,174,175,176,177,178,179,180,181,182,183,184,185,186,187,188,189,190,191,192,193,194,195,196,197,198,199,200,201,202,203,204,205,206,207,208,209,210,211,212,213,214,215,216,217,218,219,220,221,222,223,224,225,226,227,228,229,230,231,232,233,234,235,236,237,238,239,240,241,242,243,244,245,246,247,248,249,250,251,252,253,254,255,256,257,258,259,260,261,262,263,264,265,266,267,268,269,270,271,272,273,274,275,276,277,278,279,280,281,282,283,284,285,286,287,288,289,290,291,292,293,294,295,296,297,298,299,300,301,302,303,304,305,306,307,308,309,310,311,312,313,314,315,316,317,318,319,320,321,322,323,324,325,326,327,328,329,330,331,332,333,334,335,336,337,338,339,340,341,342,343,344,345,346,347,348,349,350,351,352,353,354,355,356,357,358,359,360,361,362,363,364,365,366,367,368,369,370,371,372,373,374,375,376,377,378,379,380,381,382,383,384,385,386,387,388,389,390,391,392,393,394,395,396,397,398,399,400,401,402,403,404,405,406,407,408,409,410,411,412,413,414,415,416,417,418,419,420,421,422,423,424,425,426,427,428,429,430,431,432,433,434,435,436,437,438,439,440,441,442,443,444,445,446,447,448,449,450,451,452,453,454,455,456,457,458,459,460,461,462,463,464,465,466,467,468,469,470,471,472,473,474,475,476,477,478,479,480,481,482,483,484,485,486,487,488,489,490,491,492,493,494,495,496,497,498,499,500,501,502,503,504,505,506,507,508,509,510,511,512,513,514,515,516,517,518,519,520,521,522,523,524,525,526,527,528,529,530,531,532,533,534,535,536,537,538,539,540,541,542,543,544,545,546,547,548,549,550,551,552,553,554,555,556,557,558,559,560,561,562,563,564,565,566,567,568,569,570,571,572,573,574,575,576,577,578,579,580,581,582,583,584,585,586,587,588,589,590,591,592,593,594,595,596,597,598,599,600,601,602,603,604,605,606,607,608,609,610,611,612,613,614,615,616,617,618,619,620,621,622,623,624,625,626,627,628,629,630,631,632,633,634,635,636,637,638,639,640,641,642,643,644,645,646,647,648,649,650,651,652,653,654,655,656,657,658,659,660,661,662,663,664,665,666,667,668,669,670,671,672,673,674,675,676,677,678,679,680,681,682,683,684,685,686,687,688,689,690,691,692,693,694,695,696,697,698,699,700,701,702,703,704,705,706,707,708,709,710,711,712,713,714,715,716,717,718,719,720,721,722,723,724,725,726,727,728,729,730,731,732,733,734,735,736,737,738,739,740,741,742,743,744,745,746,747,748,749,750,751,752,753,754,755,756,757,758,759,760,761,762,763,764,765,766,767,768,769,770,771,772,773,774,775,776,777,778,779,780,781,782,783,784,785,786,787,788,789,790,791,792,793,794,795,796,797,798,799,800,801,802,803,804,805,806,807,808,809,810,811,812,813,814,815,816,817,818,819,820,821,822,823,824,825,826,827,828,829,830,831,832,833,834,835,836,837,838,839,840,841,842,843,844,845,846,847,848,849,850,851,852,853,854,855,856,857,858,859,860,861,862,863,864,865,866,867,868,869,870,871,872,873,874,875,876,877,878,879,880,881,882,883,884,885,886,887,888,889,890,891,892,893,894,895,896,897,898,899,900,901,902,903,904,905,906,907,908,909,910,911,912,913,914,915,916,917,918,919,920,921,922,923,924,925,926,927,928,929,930,931,932,933,934,935,936,937,938,939,940,941,942,943,944,945,946,947,948,949,950,951,952,953,954,955,956,957,958,959,960,961,962,963,964,965,966,967,968,969,970,971,972,973,974,975,976,977,978,979,980,981,982,983,984,985,986,987,988,989,990,991,992,993,994,995,996,997,998,999,1000] 1 1 4 22 1 2 0 [0.05,0.5,0.95] 1 2 0 -1460 9 PM 14. jouta 2006 16:17 pmea 5. syyta 2008 11:09 48,24 1,0,-23,1440,799,17 2,102,90,476,224 Arial Narrow, 13 0,Model Intarese_wp3_1,2,2,0,1,M:\Nitrate_UK.ana No units Number of infants < 6 months in each country Population_age_struc[Age_categories1='0-4']/8 768,168,1 48,24 2,0,-23,1441,800 2,0,-23,1440,799,0,MIDM 2,523,149,421,266,0,MIDM [0,1,1,0] No units Table(Age_categories1)( 287K,312K,421K,166K,3.88M,4.63M,2.88M,1.12M,3.18M,2.61M,1.85M,582K,701K,609K,154K,0,0,0) 768,88,1 48,29 2,0,-23,1440,799 2,0,-23,1440,799,0,MIDM 2,136,148,419,484,0,MIDM [Age_categories1] [Age_categories1] Background prelevance of iMetHb UNKNOWN CURRENTLY!!!!!!!!!! Lognormal( 1, , , 1 ) 608,128,1 52,28 2,0,-23,1280,952 2,0,-23,1281,953,1,PDFP [1,0,0,0] [Variable Excess_cases_of_ime2] ['0-4','5-9','10-14','15-19','20-24','25-29','30-34','35-39','40-44','45-49','50-54','55-59','60-64','65-69','70-74','75-79','80-84','>85'] 192,64,1 48,24 2,0,-23,1440,799 [] ['0-4','5-9','10-14','15-19','20-24','25-29','30-34','35-39','40-44','45-49','50-54','55-59','60-64','65-69','70-74','75-79','80-84','>85'] % Percentage of bottle fed infants <6 months in Finland (2005) Imeväisikäisten ruokinta Suomessa vuonna 2005 Kaija Hasunen, Sanna Ryynänen Selvityksiä 2005:19 ISBN 952-00-1800-X (PDF), 952-00-1799-2 (nid.), ISSN 1236-2115 Triangular( 0.48, 0.51, 0.73 ) 608,192,1 52,28 2,0,-23,1280,952 2,0,-23,1281,953,1,PDFP [1,0,0,0] [Variable Excess_cases_of_ime2] No units Excess_rate_of_imet1*Infants__6_months*Background_prelevanc/100000*Percentage_of_bottle 768,320,1 48,40 2,102,90,476,224 2,40,50,793,499,1,STAT {!40000|Att_contlinestyle Graph_pdf_valdim:6} {!40000|Att_graphvaluerange Graph_pdf_valdim:1,0,1,1,0} Probindex:[0.5 ] [Areas_in_england_and,Areas_in_england_and,2,1] [Index Age_categories1, Index Areas_in_england_and] [1,0,0,0] [Sys_localindex('STATISTICS'),1,Areas_in_england_and,1] No units (exp(Slope_of_exposure_re*Total_daily_ingestio)-1) 448,320,1 48,31 2,0,-23,1441,800 2,0,-23,1440,799,0,MIDM 2,40,50,581,368,1,MIDM [] [] [Object Variable] [1,0,0,0] [Scenarios,1,Water_companies,1,Sys_localindex('STEP'),1] These variables defined using author judgement 608,184,-1 72,96 1,0,0,1,0,1,0,,0, mg/l Concentration of NO3- in drinking water in UK (2001) Table(Areas_in_england_and)( LogNormal (18.9,,, 2.34),LogNormal(26.25,,, 2.34),LogNormal (16.35,,,10.9),LogNormal (38.85,,,0.9),LogNormal (34.071,,,0.001),LogNormal (3.0007,,,5.009),LogNormal (25.539,,,10.2),LogNormal(20.4655,,,9.231),LogNormal (28.45,,,6.862),LogNormal(5.43,,,0.8788),LogNormal(18.7,,,8.223),LogNormal (3.9753,,,595),LogNormal(2.865,,,5.777),LogNormal(28.891,,,3.782),LogNormal (16.828,,,1.11),LogNormal (18.75,,,0.22),LogNormal(19.56125,,,9.113),LogNormal (30.03,,,8.132),LogNormal (4.8454,,,8.516),LogNormal (6.167,,, .03),LogNormal(27.835,,,5.515),LogNormal (28,,,6.615),LogNormal (21.243,,,11.88),LogNormal (4.80565,,,3.023),LogNormal (6.2882,,,12.02)) 64,320,1 48,38 2,0,-23,1440,799 2,0,-23,1422,791,0,MIDM 2,-50,24,1440,799,1,PDFP {!40000|Att_graphvaluerange Graph_pdf_valdim:1,0,0,1,,,,0,20} {!40000|Att_graphvaluerange A:1,,0,,0,0,,0,60} {!40000|Att_contlinestyle Graph_pdf_valdim:6} [Areas_in_england_and] [Areas_in_england_and,Areas_in_england_and,Undefined,Undefined,1] [] [1,0,0,0] [Variable Excess_cases_of_ime2] [2,1,4,4,4,0] ['ang','bou','brw','caw','cho','dcc','eas','ess','fol','har','mik','nor','nww','por','sea','sev','sos','sou','sww','teh','tha','thr','wes','wrx','yor'] 64,64,1 48,29 2,0,-23,1433,792 ['ang','bou','brw','caw','cho','dcc','eas','ess','fol','har','mik','nor','nww','por','sea','sev','sos','sou','sww','teh','tha','thr','wes','wrx','yor'] mg/kg/d A*Total_daily_consump/ Weight 216,320,1 68,40 2,0,-23,1441,800 2,0,-23,1440,799,0,MIDM 2,0,-23,1440,799,1,MIDM {!40000|Graph_keylabelcolor:0,0,0} {!40000|Graph_keytextcolor:0,0,0} {!40000|Graph_axislabelcolor:0,0,0} {!40000|Graph_axistitlecolor:0,0,0} {!40000|Graph_pagebrush:65280,65280,65280} {!40000|Att_catlinestyle Graph_primary_valdim:9} [] [] 1,,,,,,10 [Water_source,1,Age_group,1,Country,1,Data,1] [Data,1,Country,1,Water_source,1] l/day Lognormal( , , 0.240, 0.800 ) 280,192,1 96,36 2,0,-23,1441,800 2,0,-23,1433,792,0,STAT [Variable Excess_cases_of_ime2] http://rais.ornl.gov/homepage/DRAFT_EXPOSURE_HANDBOOK.pdf kg Distribution of weight for infants < 6 months of age Lognormal( , , 5, 2 ) 128,192,1 48,24 2,0,-23,1441,800 2,392,402,416,303,1,PDFP [1,0,0,0] [Variable Excess_cases_of_ime2] mg/kg/d Nitrate toxicity value for infants U.S. EPA has evaluated the noncancer oral data for nitrate and derived a reference dose (RfD) of 1.6 mg/kg-day with 10 % of risk to MetHb. 0.065850 448,192,1 68,38 2,0,-23,1281,953 2,0,-23,1440,799,0,MIDM 2,0,-23,1440,799,1,MIDM [] [] [Variable Excess_cases_of_ime2] ProbBands(Total_daily_ingestio) 216,448,1 68,48 2,0,-23,1280,952,1,MIDM [Areas_in_england_and,Undefined] [Sys_localindex('PROBABILITY'),2,Areas_in_england_and,1] ProbBands(Excess_rate_of_imet1) 448,448,1 48,46 2,0,-23,1281,953,1,MIDM [Areas_in_england_and,Undefined] [Sys_localindex('PROBABILITY'),2,Areas_in_england_and,1] ProbBands(Excess_cases_of_imet) 768,448,1 48,46 2,0,0,1281,953,0,MIDM [Areas_in_england_and,Undefined] [Sys_localindex('PROBABILITY'),3,Areas_in_england_and,1] ProbBands(A) 64,448,1 56,40 2,0,-23,1281,953,1,MIDM Probindex:[0.05, 0.5, 0.95 ] [Areas_in_england_and,Undefined] [Sys_localindex('PROBABILITY'),2,Areas_in_england_and,1] pmea 5. syyta 2008 9:59 48,24 960,72,1 48,24 1,0,1,1,1,1,0,,0, 1,0,-23,1440,799,17 Abs( RankCorrel( Excess_cases_of_ime2, Excess_cases_of_imet ) ) 288,96,1 48,46 1,1,1,1,1,1,0,0,0,0 2,0,-23,1440,799,1,MIDM Flip:8 [Excess_cases_of_ime2,Undefined] [Index Areas_in_england_and] [Areas_in_england_and,-1,Excess_cases_of_ime2,1] [ Background_prelevanc, Percentage_of_bottle, A, Total_daily_consump, Weight, Slope_of_exposure_re] ['Background prelevance of iMetHb','Percentage of bottle fed infants','[NO3-] in drinking water in England and Wales','Total daily consumption of drinking water by infants < 6 months','Weight','Slope of exposure-response function for nitrate and iMetHb'] 96,96,1 48,38 1,1,1,1,1,1,0,0,0,0 [Background_prelevanc,Percentage_of_bottle,A,Total_daily_consump,Weight,Slope_of_exposure_re] These variables defined using author judgement 280,176,-1 100,56 1,0,0,1,0,1,0,,0, ktluser 10. huhta 2008 12:14 48,24 960,128,1 48,24 1,4,31,1185,552,17 {Daly_valuation}; {Concentration_of_ni 984,264,1 60,28 [Variable Background_prevalen2, Objective Total_met_hb_mortal3] [Objective Dalys_and_or_financ2] [1] 984,328,1 64,20 2,0,-23,1152,763 [Objective Attributable_burden2] 0 384,272,1 60,32 [Variable Concentration_of_ni7, Variable Removal_of_nitrates1] [Variable Total_daily_consump7] [1,Raw_water_quality1,Concentration_of_ni6,Concentration_of_ni7,Removal_of_nitrates1] 544,112,1 72,28 [Variable Total_daily_consump6] Lognormal( 1 ) 232,112,1 48,32 2,166,180,476,224 [Constant Usage_of_nitrate_fe3] [1,Usage_of_nitrate_fe3] 232,272,1 48,32 [Variable Concentration_of_ni4] [1,Daily_sales_of_bott2] 784,184,1 48,32 [Variable Total_daily_consump6, Variable Total_daily_consump7] 888,440,1 48,28 {Dbp_dalys}; {Mirobes_dalys} 1112,264,1 48,28 [Objective Attributable_burden2, Variable Daly_and_or_cost_we2] 0 1112,112,1 48,32 [Objective Dalys_and_or_financ2] 5 96,272,1 68,32 {Chlorination}; {Dose_response_of_mi; Water_treatment_meth 992,112,1 64,28 [Objective Total_met_hb_mortal3] 736,440,1 48,29 [Variable Total_daily_consump7] 0 96,112,1 68,32 0 680,184,1 40,32 chemical and microbial quality of raw water [1] 384,440,1 52,28 {Dbp_exposure_via_dr; Dbp_exposure_via_oth; Dose_response_of_dbp 544,376,1 72,24 [Variable Standard_for_nitrat3, Constant Water_treatment_met3] [Variable Concentration_of_ni4] [1,Drinking_water_legi2] 96,376,1 64,24 2,0,0,1025,668 [Variable Removal_of_nitrates1] Actions 88,48,-1 48,24 Sources 232,48,-1 48,24 Media 368,48,-1 48,24 Exposure 704,48,-1 48,24 Impacts 992,48,-1 44,24 Valuation 1104,48,-1 48,24 0 728,112,1 92,28 [Variable Concentration_of_ni5, Variable Daily_consumption_o2] 1 736,376,1 100,24 2,102,90,476,224 [Variable Concentration_of_ni4, Variable Daily_consumption_o2, Constant Population_using_pr2] [1,Total_daily_consump6,Total_daily_consump7,Proportion_of_boile2,Population_demandin2] 728,264,1 92,24 2,102,90,476,224 [Objective Total_met_hb_mortal3] {Daly_valuation}; {Dbp_health_effects} 984,184,1 64,32 [Variable Exposure_response_f1, Variable Total_ingestion_of_3] [Objective Attributable_burden2] 216,440,1 48,29 [Chance Concentration_of_ni6] none water treatment methods [1] 544,440,1 48,28 2,0,0,1025,668 [Variable Removal_of_nitrates1] ktluser 11. kesta 2008 12:21 48,24 960,184,1 48,24 1,0,0,1440,799,1 Arial Narrow, 13 This model is built for INTARESE project, WP3.4. The risk assessment behind the model is on INTARESE wiki http://heande.pyrkilo.fi/heande/index.php/Risk_assessment_of_nitrate_in_drinking_water This model uses 2003 data when appropriate and possible 256,96,-1 184,68 Contains data that comes from a referrable source. The reference must be mentioned in the Reference attribute. Colour 3R1B. 1 232,504,1 48,24 2,102,90,476,516 65535,52427,65534 Contains data that comes from a non-referrable source, i.e. some general knowledge or author judgement. Colour 4R2B. 1 232,560,1 48,24 52425,39321,65535 Contains information about general issues related to the structure and content of a model. Text is written to Description. Each addition is started with the date and the name of the user. The title of the node is Loki n or Log n (n=version number of the model). You should not write information related to a particular node, that should be written in the node itself so that the information will be inherited with the node. Colour 4L3B. 1 120,632,1 48,24 65535,54067,19661 Argument about a node, data, or relationship in a model; or a description of its importance. Colour: automatic (2L3B). 1 344,448,1 48,24 65535,31131,19661 This is the basic building block of an Analytica model. It is a variable that defines a (typically) measurable entity. Usually it is calculated based on data on and relationships about its causes. 1 232,448,1 48,24 Modules are used to create a hierarchical structure. Modules may contain nodes and other modules inside them. mtad 16. Aprta 2003 12:56 48,24 120,584,1 48,24 1,40,0,505,406,17 A conclusion is basically an argument. The colour is used to enhance the fact that the data for this argument originates from the results of the model. Colour 6L3B. 1 344,560,1 48,24 2,44,90,476,224 65535,65532,19661 Index related to the node beside it. Indexes should be as close as possible to the place where they are used. Otherwise there is the risk of a connection brake. Colour: automatic (5R2B). [0] 120,484,1 48,24 2,341,157,476,224 Colour description: xLyT describes the coordinates in the colour palette, xth cell from left and yth cell from top. Directions are L left, R right, T top, B bottom, e.g. 1R1B is the right bottom cell. 560,480,-1 112,44 Decision mode defines a decision under analysis. Other decisions (such as those decided by someone else) can be defined as uncertain variables instead of decisions. 0 120,448,1 48,24 Outcome of interest. The optimisation of this variable is often defined as the criteria for choosing between decision options. 0 120,528,1 48,24 An uncertain variable that is defined as a probability distribution. 0 232,616,1 48,24 A value or preference. Colour 8L4B. 0 344,616,1 48,24 5,65535,1 Pyrkilo diagram method (or structured deliberation as it is sometimes called) has been developed to facilitate the Science-Policy Interface. There is a need for methods facilitating the flow of information and understanding between science and policy. The principle is to describe a risk situation in a formal manner. Pyrkilo is an enhanced causal diagram that contains items along a causal pathway (or network) from e.g. abatement strategies to emissions to dispersion to exposure to effects. It has been designed to describe also other than causal connections such as non-causal reasoning, values, preferences, and arguments. These diagrams use Analytica(TM) platform, a graphical Monte Carlo simulation program. It is based on nodes (or variables or objects). They are used to describe and define all the pieces needed for a description of the situation under scrutiny. Many nodes are used as described in Analytica manuals. However, there are also special colours and shapes representing features that are important for pyrkilo diagrams. See Description of each node for more details. You can see the definitions and descriptions by clicking or double-clicking the nodes. 472,231,-1 400,87 2,402,92,530,558 A scope node is basically an argument. The bevel is used to enhance the fact that the argument is about the scope of the model, (i.e. about the existence of a node or module). Colour: automatic (2L3B). 1 344,504,1 48,24 1,1,1,1,1,1,0,,1, 65535,31131,19661