Dynamic simulation periods are specified in Time's definition. This is usually a list of numbers or labels, typically in some unit of time (days, weeks, months, etc.). Use the ÒDynamic()Ó function in your variables to perform dynamic simulation.
0
0
1
1
2
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Focus+scope
Moderator
References
INTARESE WP3.4
PM
14. jouta 2006 16:17
ktluser
15. touta 2008 15:49
48,24
1,1,0,448,245,17
2,102,90,476,224
Arial Narrow, 13
0,Model Intarese_wp3_4,2,2,0,1,C:\Analytica models\Nitrate.ANA
Risk model
Päivi
11. tamta 2008 10:45
48,24
176,48,1
48,24
1,0,0,1440,799,17
Population age structure
[1]
512,48,1
48,24
Country
['Finland','UK','Spain','Hungary','Romania']
504,112,1
48,24
2,102,90,476,224
['Finland','UK','Spain','Hungary','Romania']
Exposure model
ktluser
28. maata 2008 10:20
48,24
232,64,1
48,24
1,0,-23,1440,626,17
Source of drinking water
%
Percentage of population using tap and well water
Table(Country,Water_source)(
0.06,0.94,
0,0,
0,0,
0,0,
0,0
)
160,48,1
48,29
2,0,-23,1440,799
2,0,-23,1072,555,0,MIDM
[Water_source,Country]
[Undefined,Undefined]
[Variable Total_daily_consump1, Variable Total_daily_consump3]
Proportion of boiled drinking water
0
480,56,1
40,32
Total daily consumption of drinking water from public supply by infants < 6 months
l/day
Truncate( Normal (0.240, 0.247), 0, 0.800 )
312,152,1
92,28
2,0,-23,1072,555
2,0,-23,1072,555,1,STAT
[Constant Source_of_drinking_w, Variable Infants__6_months]
[Objective Total_ingestion]
http://rais.ornl.gov/homepage/DRAFT_EXPOSURE_HANDBOOK.pdf
Total daily consumption of privately supplied drinking water by infacts < 6 months
l/d
({Population_size}*Source_of_drinking_w*Daily_consumption_o1)
104,152,1
64,44
2,14,227,1072,555
[Constant Source_of_drinking_w, Variable Infants__6_months, Chance No3_well]
[Objective Total_ingestion]
Total ingestion of nitrates in drinking water by infacts < 6 months
Table(Country,Water_source,Data,Age_group)(
'’’I’f Local_water_data[Source=’Tap water*] >1 then x else No3_tap ’',0,
0,0,
0,0,
'Local_water_data[Source=’Tap water*] ',0,
0,0,
0,0,
0,0,
0,0,
0,0,
0,0,
0,0,
0,0,
0,0,
0,0,
0,0,
0,0,
0,0,
0,0,
0,0,
0,0,
0,0,
0,0,
0,0,
0,0,
0,0,
0,0,
0,0,
0,0,
0,0,
0,0
)
200,272,1
52,36
2,0,-23,1440,799
2,0,-23,1440,799,0,MIDM
[Water_source,Data]
[Data,Country]
[Variable Total_daily_consump1, Variable Total_daily_consump3]
[Objective Total_met_hb_mortal1]
[Water_source,1,Age_group,1,Country,1,Data,1]
[Data,1,Age_group,1,Country,1,Water_source,1]
Infants <6 months
Number of infants < 6 months in each country
Table(Country)(
28.6792K,0,0,0,0)
312,48,1
48,24
2,0,-23,1440,799
2,0,-23,1072,555,0,MIDM
[]
[Variable Total_daily_consump1, Variable Total_daily_consump3]
Risk level for NO3-
mg/l
The risk limit for symptomatic methemoglobinemia due to nitrate in drinking water
100
480,392,1
48,24
2,0,-23,1431,789
Population size
Table(Country)(
5.194901M,0,0,0,0)
472,456,1
48,24
2,0,-23,1072,555
Water source
Drinking water sources: Treated tap water or untreated water from private well
['Tap water','Well water']
488,240,1
48,24
['Tap water','Well water']
Health effects
ktluser
28. maata 2008 10:20
48,24
232,184,1
48,24
1,0,-23,1440,799,17
Attributable burden of disease to nitrates in drinking water
{Daly_valuation};
{Concentration_of_ni
104,160,1
60,28
[Variable Background_prevalen1, Objective Total_met_hb_mortal1]
[Objective Dalys_and_or_financ1]
Background prevalence of Met-Hb
[1,Infection_status_of_]
288,160,1
64,20
2,0,-23,1152,763
[Objective Attributable_burden1]
DALYs and/or financial costs
{Dbp_dalys};
{Mirobes_dalys}
(Risk_estimate)
104,264,1
48,28
[Objective Attributable_burden1, Variable Daly_and_or_cost_we1]
[]
DALY and/or cost weightings
0
288,264,1
48,32
[Objective Dalys_and_or_financ1]
Total met-Hb mortality and morbidity due to nitrates in drinking water
{Daly_valuation};
{Dbp_health_effects}
104,56,1
64,32
[Objective Total_ingestion, Chance Exposure_response]
[Objective Attributable_burden1]
Infection status of infants < 6 months
432,160,1
48,24
NOEL for NO3-
mg/l
No effect level (NOEL) for nitrate in drinking water
100
704,56,1
48,24
Health risk estimate for infant MetHg
Table(Water_source,Reference)(
'’(Total_ingestion_[Age_group=’Child’, Source=’Tap water’,Data=’Distribution’]/Exposure_response[Reference=’TCA/TDI’])’','(Exposure_response[Reference=’NOAEC/LOAEC/NOAEL/LOAEL’]/Total_ingestion[Age_group=’Infant’,Source=’Tap water’,Data=’Distribution’])’',
'’(Total_ingestion_[Age_group=’Child’, Source=’Well water’,Data=’Distribution’]/Exposure_response[Reference=’TCA/TDI’])’','(Exposure_response[Reference=’NOAEC/LOAEC/NOAEL/LOAEL’]/Total_ingestion[Age_group=’Infant’,Source=’Well water’,Data=’Distribution’])’'
)
704,144,1
60,32
2,0,-23,1440,799
2,0,-23,1440,799,0,MIDM
[Reference,Water_source]
[Water_source,Reference]
Risk estimate 2
656,24,-1
48,24
Risk estimate 1
64,24,-1
48,24
RC
Risk characterisation approach
['Hazard quotient','Margin of safety']
872,56,1
48,24
Reference
['TCA/TDI','NOAEC/LOAEC/NOAEL/LOAEL']
864,128,1
48,24
['TCA/TDI','NOAEC/LOAEC/NOAEL/LOAEL']
Data
['Distribution','Average','Max']
864,216,1
48,24
['Distribution','Average','Max']
Dose response model
ktluser
28. maata 2008 10:20
48,24
384,64,1
48,24
1,0,-23,1440,799,17
Exposure-response function for nitrate and iMetHg
If Total_ingestion >100 then 'Yes' else 'No'
112,88,1
68,36
2,0,-23,1440,799
[Data,Country]
[Objective Total_met_hb_mortal1]
Sources
ktluser
28. maata 2008 10:20
48,24
72,64,1
48,24
1,0,-23,1440,799,17
[NO3] in drinking water from well
If Local_data_well=Na, then General_well else Local_well
80,280,1
60,40
2,0,-23,1440,799
2,0,752,1440,799,0,MIDM
[Object Variable, Variable General_tap, Variable Local_data_well]
[Variable Total_daily_consump3]
[NO3] in drinking water from tap
If Local_data_tap=Na, then General_tap else Loca_water_tap
248,280,1
60,40
2,0,-23,1440,799
2,0,-23,1440,799,0,MIDM
[Variable Local_data_tap, Variable General_well]
Drinking water legistation and guidance levels on nitrates
mg NO3-/l
Nitrate concentration in drinking water. EU Directive 80/778/ETY for waterworks >5000 people of production >1000m3/d
50
472,104,1
68,32
[Variable Standard_for_nitrat2]
Standard for nitrate
mg NO3-/l
Table(Country)(
50,50,50,50,50)
472,192,1
48,24
2,0,-23,1440,799
[Decision Drinking_water_legi1]
[]
Local data on [NO3-] in tap water
Table(Country,Finland_areas_nuts2)(
'Normal (3.6875, 1.021804688)’','’’Normal (1.3125, 0.961304917)','’Normal (2.0625, 2.321291205)','’Normal (3.6875, 2.890100097)',
'Na','Na','Na','Na',
'Na','Na','Na','Na',
'Na','Na','Na','Na',
'Na','Na','Na','Na'
)
248,32,1
48,29
2,0,-23,1440,799
2,0,0,1431,789,0,MIDM
2,0,-23,1432,789,1,MIDM
[Country,Finland_areas_nuts2]
[Finland_areas_nuts2,Country]
[Chance No3_tap]
[Rc,2,Finland_areas_nuts2,1,Country,1]
De1
1
472,120,-3
76,128
1,1,1,0,1,1,0,,0,
65535,65535,65535
Needed for risk evaluation?
456,32,-1
48,24
General [NO3-] concentration in tap water
Table(Country,Water_source)(
Normal (1,0),0,
Normal (1,0),0,
Normal (1,0),0,
Normal (1,0),0,
Normal (1,0),0
)
80,112,1
48,38
2,0,-23,1440,799
2,0,-23,1440,799,0,MIDM
2,0,-23,1440,799,0,MIDM
[Water_source,Country]
[Water_source,Country]
[Chance No3_well]
Local data on [NO3-] in well water
Table(Country,Finland_areas_nuts2)(
'Na','Na','Na','Na',
'Na','Na','Na','Na',
'Na','Na','Na','Na',
'Na','Na','Na','Na',
'Na','Na','Na','Na'
)
80,32,1
48,29
2,102,90,476,224
[Finland_areas_nuts2,Country]
[Chance No3_well]
General [NO3-] concentration in well water
248,120,1
48,29
[Chance No3_tap]
Finland areas NUTS2
[' FI18',' FI19',' FI13',' FI1A']
480,312,1
48,24
2,0,-119,1432,790
[' FI18',' FI19',' FI13',' FI1A']
Age group
Age groups: Infant (< 6 monts), Adult
['Infant ','Adult']
496,176,1
48,24
['Infant ','Adult']
Conceptual model
ktluser
10. huhta 2008 12:14
48,24
56,48,1
48,24
1,0,0,1431,789,17
Attributable burden of disease to nitrates in drinking water
{Daly_valuation};
{Concentration_of_ni
976,256,1
60,28
[Variable Background_prevalen2, Objective Total_met_hb_mortal3]
[Objective Dalys_and_or_financ2]
Background prevalence of Met-Hb
[1]
976,320,1
64,20
2,0,-23,1152,763
[Objective Attributable_burden2]
Concentration of nitrates in drinking water from private supply
0
376,264,1
60,32
[Variable Concentration_of_ni7, Variable Removal_of_nitrates1]
[Variable Total_daily_consump7]
Concentration of nitrates in drinking water from public supply
[1,Raw_water_quality1,Concentration_of_ni6,Concentration_of_ni7,Removal_of_nitrates1]
536,104,1
72,28
[Variable Total_daily_consump6]
Concentration of nitrates in surface water
Lognormal( 1 )
224,104,1
48,32
2,166,180,476,224
[Constant Usage_of_nitrate_fe3]
Concentration of nitrates in ground water
[1,Usage_of_nitrate_fe3]
224,264,1
48,32
[Variable Concentration_of_ni4]
Daily consumption of bottled water by infacts <6 months
[1,Daily_sales_of_bott2]
776,176,1
48,32
[Variable Total_daily_consump6, Variable Total_daily_consump7]
Daily sales of bottled water
880,432,1
48,28
DALYs and/or financial costs
{Dbp_dalys};
{Mirobes_dalys}
1104,256,1
48,28
[Objective Attributable_burden2, Variable Daly_and_or_cost_we2]
DALY and/or cost weightings
0
1104,104,1
48,32
[Objective Dalys_and_or_financ2]
Drinking water legistation and guidance levels on nitrates
5
88,264,1
68,32
Exposure-response function
{Chlorination};
{Dose_response_of_mi;
Water_treatment_meth
984,104,1
64,28
[Objective Total_met_hb_mortal3]
Population using private water supplies
728,432,1
48,29
[Variable Total_daily_consump7]
Population demanding safe, wholesome and clean drinking water supply
0
88,104,1
68,32
Proportion of boiled drinking water
0
672,176,1
40,32
Raw water quality
chemical and microbial quality of raw water
[1]
376,432,1
52,28
Removal of nitrates by treatment
{Dbp_exposure_via_dr;
Dbp_exposure_via_oth;
Dose_response_of_dbp
536,368,1
72,24
[Variable Standard_for_nitrat3, Constant Water_treatment_met3]
[Variable Concentration_of_ni4]
Standard for nitrates
[1,Drinking_water_legi2]
88,368,1
64,24
2,0,0,1025,668
[Variable Removal_of_nitrates1]
Te1
Actions
80,40,-1
48,24
Te1
Sources
224,40,-1
48,24
Te1
Media
360,40,-1
48,24
Te1
Exposure
696,40,-1
48,24
Te1
Impacts
984,40,-1
44,24
Te1
Valuation
1096,40,-1
48,24
Total daily consumption of drinking water from public supply by infants < 6 months
0
720,104,1
92,28
[Variable Concentration_of_ni5, Variable Daily_consumption_o2]
Total daily consumption of privately supplied drinking water by infacts < 6 months
1
728,368,1
100,24
2,102,90,476,224
[Variable Concentration_of_ni4, Variable Daily_consumption_o2, Constant Population_using_pr2]
Total ingestion of nitrates in drinking water by infacts < 6 months
[1,Total_daily_consump6,Total_daily_consump7,Proportion_of_boile2,Population_demandin2]
720,256,1
92,24
2,102,90,476,224
[Objective Total_met_hb_mortal3]
Total met-Hb mortality and morbidity due to nitrates in drinking water
{Daly_valuation};
{Dbp_health_effects}
976,176,1
64,32
[Variable Exposure_response_f1, Variable Total_ingestion_of_3]
[Objective Attributable_burden2]
Usage of nitrate fertilisers in catcment
208,432,1
48,29
[Variable Concentration_of_ni6]
Water treatment method
none
water treatment methods
[1]
536,432,1
48,28
2,0,0,1025,668
[Variable Removal_of_nitrates1]