1 1 jtuomist Tue, Mar 27, 2001 11:26 jtue 8. syyta 2008 12:52 48,24 1,0,0,1,1,1,0,,0, 1,40,84,859,492,17 0,Linkmodule Vois,2,2,-32766,1,VOI analysis.ANA 100,1,1,1,2,9,4744,6798,7 - Index for making classes number of bins for classification. sequence(1/9,1,1/9) 760,64,1 48,12 (input,output) vary A function that classifies the values of output variable into classes number of different bins (defined by centiles) based on the values of the input variable. (if (input >= getfract(input,Frac-1/9) and input<getfract(input,Frac) ) then output else 0) + (if getfract(input,1)=input and Frac=1 then output else 0) 760,32,1 48,24 input,output avoided deaths/a Total VOI (EVPI) mean(max(outcome,H1898))-Nbuu 320,56,1 48,24 2,537,64,416,303,0,MIDM [H1899,Salmon1] 1,I,4,2,0,0 cases/a Expected net benefits under uncertainty max(mean(outcome),H1898) 208,56,1 48,24 1,114,51,409,331,0,MIDM cases/a classify(outcome_inputs,outcome) 208,112,1 48,24 2,155,110,843,183,0,MEAN Graphtool:0 Distresol:10 Diststeps:1 Cdfresol:5 Cdfsteps:1 Symbolsize:6 Baroverlap:0 Linestyle:1 Frame:1 Grid:1 Ticks:1 Mesh:1 Scales:1 Rotation:45 Tilt:0 Depth:70 Frameauto:1 Showkey:1 Xminimum:0 Xmaximum:1 Yminimum:0 Ymaximum:1 Zminimum:0 Zmaximum:1 Xintervals:0 Yintervals:0 Includexzero:0 Includeyzero:0 Includezzero:0 Statsselect:[1,1,1,1,1,0,0,0] Probindex:[0.05,0.25,0.5,0.75,0.95] [Frac,H1898] avoided deaths/a Collects all VOI to one table (EVPI and EVPPI). var a:= Max(mean(Nb),H1898); sum(a,Frac)-Nbuu 320,112,1 48,24 1,533,191,416,303,0,MIDM 2,165,255,741,391,0,MIDM Graphtool:0 Distresol:10 Diststeps:1 Cdfresol:5 Cdfsteps:1 Symbolsize:6 Baroverlap:0 Linestyle:10 Frame:1 Grid:1 Ticks:1 Mesh:1 Scales:1 Rotation:45 Tilt:0 Depth:70 Frameauto:0 Showkey:1 Xminimum:0 Xmaximum:1 Yminimum:0 Ymaximum:13K Zminimum:1 Zmaximum:8 Xintervals:0 Yintervals:0 Includexzero:0 Includeyzero:0 Includezzero:0 Statsselect:[1,1,1,1,1,0,0,0] Probindex:[0.05,0.25,0.5,0.75,0.95] Arial, 2 1,I,6,2,0,0 1 56,56,1 48,46 Outcome Table(outcome_inputs1)( Impr_in_feed,Pollutant_scare,All_or_chd,Erf_hcrude,Benefit_limit,Crude_salmon,Fraction_farmed,H1907,Poll_or_net,Poll_i_types[Pollutant1='Dieldrin', Salmon1='Farmed salmon'],Poll_i_types[Pollutant1='Toxaphene', Salmon1='Farmed salmon'],Poll_i_types[Pollutant1='PCB', Salmon1='Farmed salmon'],A,Regulate_pollutants_,Recommend) ['Pollutant levels in fish feed after lower limits (S+P)','Salmon consumption after feed limits (S+P)','Does omega-3 help CHD patients or everyone? (S)','Dose-response of health benefit (S)','Highest omega-3 dose with health benefit (S)','Current average consumption of salmon (S)','Fraction of farmed from total salmon use (S)','Omega3 content in salmon (S)','Consider pollutant or net health effect? (P)','Dieldrin concentration in farmed salmon (S)','Toxaphene concentration in farmed salmon (S)','PCB concentration in farmed salmon (S)','Farmed salmon use after recommendation (S)','Lower limits for pollutants in fish feed? (P)','Recommend restricted farmed salmon consumption? (P)'] 752,112,1 48,24 1,1,1,1,1,1,0,0,0,0 2,377,196,476,275 2,443,237,688,342,0,MIDM 2,168,178,582,361,0,MIDM [Self,Self] rank correlation Abs( RankCorrel( Outcome_inputs, Outcome ) ) 208,168,1 48,24 1,1,1,1,1,1,0,0,0,0 2,523,32,715,354,0,MIDM [H1898,Outcome_inputs1] 1 56,240,1 48,46 Outcome2 avoided deaths/a Total VOI (EVPI) mean(max(outcome2,H1899))-Nbuu1 320,240,1 48,24 2,559,23,416,303,0,MIDM [H1899,Salmon1] cases/a Expected net benefits under uncertainty max(mean(outcome2),H1899) 208,240,1 48,24 1,114,51,409,331,0,MIDM cases/a classify(outcome_inputs,outcome2) 208,296,1 48,24 2,45,47,932,338,0,SAMP Graphtool:0 Distresol:10 Diststeps:1 Cdfresol:5 Cdfsteps:1 Symbolsize:6 Baroverlap:0 Linestyle:1 Frame:1 Grid:1 Ticks:1 Mesh:1 Scales:1 Rotation:45 Tilt:0 Depth:70 Frameauto:1 Showkey:1 Xminimum:0 Xmaximum:1 Yminimum:0 Ymaximum:1 Zminimum:0 Zmaximum:1 Xintervals:0 Yintervals:0 Includexzero:0 Includeyzero:0 Includezzero:0 Statsselect:[1,1,1,1,1,0,0,0] Probindex:[0.05,0.25,0.5,0.75,0.95] [Frac,H1899] avoided deaths/a Collects all VOI to one table (EVPI and EVPPI). var a:= Max(mean(Nb1),H1899); sum(a,Frac)-Nbuu1 320,296,1 48,24 1,533,191,416,303,0,MIDM 2,61,82,685,383,0,MIDM Graphtool:0 Distresol:10 Diststeps:1 Cdfresol:5 Cdfsteps:1 Symbolsize:6 Baroverlap:0 Linestyle:10 Frame:1 Grid:1 Ticks:1 Mesh:1 Scales:1 Rotation:45 Tilt:0 Depth:70 Frameauto:0 Showkey:1 Xminimum:0 Xmaximum:1 Yminimum:0 Ymaximum:13K Zminimum:1 Zmaximum:8 Xintervals:0 Yintervals:0 Includexzero:0 Includeyzero:0 Includezzero:0 Statsselect:[1,1,1,1,1,0,0,0] Probindex:[0.05,0.25,0.5,0.75,0.95] Arial, 2 [Pollutant1,Outcome_inputs] 1,I,6,2,0,0 rank correlation Abs( RankCorrel( Outcome_inputs, Outcome2 ) ) 208,352,1 48,24 1,1,1,1,1,1,0,0,0,0 2,577,431,673,383,0,MIDM [H1899,Outcome_inputs1] var b:= nb1; var c:=0; var x:=1; while x<=samplesize do (c:=c+b[run=x]; x:=x+1); var d:= c/samplesize; var a:= Max(d,H1899); sum(a,Frac)-Nbuu1; x 320,352,1 48,24 2,446,377,658,349,0,MIDM [Frac,Outcome_inputs] 1,I,4,2,0,0 index a:= ['Total VOI']; index b1:= concat(a,outcome_inputs1); index b2:= concat(a,outcome_inputs1); index d:= concat(b1,b2); var c:= (if a='Total VOI' then total_voi1 else 0); var e:= concat(c,v3,a,outcome_inputs1,b1); var f:= (if a='Total VOI' then total_voi2 else 0); var g:= concat(f,v1,a,outcome_inputs1,b2); var h:= concat(e,g,b1,b2,d); h 432,184,1 48,24 2,217,23,532,727,0,MIDM Graphtool:0 Distresol:10 Diststeps:1 Cdfresol:5 Cdfsteps:1 Symbolsize:6 Baroverlap:0 Linestyle:1 Frame:1 Grid:1 Ticks:1 Mesh:1 Scales:1 Rotation:45 Tilt:0 Depth:70 Frameauto:1 Showkey:1 Xminimum:0 Xmaximum:1 Yminimum:0 Ymaximum:1 Zminimum:0 Zmaximum:1 Xintervals:0 Yintervals:0 Includexzero:0 Includeyzero:0 Includezzero:0 Statsselect:[1,1,1,1,1,0,0,0] Probindex:[0.05,0.25,0.5,0.75,0.95] ['Pollutant levels in fish feed after lower limits (S+P)','Salmon consumption after feed limits (S+P)','Does omega-3 help CHD patients or everyone? (S)','Dose-response of health benefit (S)','Highest omega-3 dose with health benefit (S)','Current average consumption of salmon (S)','Fraction of farmed from total salmon use (S)','Omega3 content in salmon (S)','Consider pollutant or net health effect? (P)','Dieldrin concentration in farmed salmon (S)','Toxaphene concentration in farmed salmon (S)','PCB concentration in farmed salmon (S)','Farmed salmon use after recommendation (S)','Lower limits for pollutants in fish feed? (P)','Recommend restricted farmed salmon consumption? (P)'] 752,168,1 48,24 1,1,1,1,1,1,0,0,0,0 2,102,90,476,469 2,351,356,688,342,0,MIDM 2,168,178,582,361,0,MIDM [Self,Self] ['Pollutant levels in fish feed after lower limits (S+P)','Salmon consumption after feed limits (S+P)','Does omega-3 help CHD patients or everyone? (S)','Dose-response of health benefit (S)','Highest omega-3 dose with health benefit (S)','Current average consumption of salmon (S)','Fraction of farmed from total salmon use (S)','Omega3 content in salmon (S)','Consider pollutant or net health effect? (P)','Dieldrin concentration in farmed salmon (S)','Toxaphene concentration in farmed salmon (S)','PCB concentration in farmed salmon (S)','Farmed salmon use after recommendation (S)','Lower limits for pollutants in fish feed? (P)','Recommend restricted farmed salmon consumption? (P)'] ['Total VOI','Pollutant levels in fish feed after lower limits (S+P)','Salmon consumption after feed limits (S+P)','Does omega-3 help CHD patients or everyone? (S)','Dose-response of health benefit (S)','Highest omega-3 dose with health benefit (S)','Current average consumption of salmon (S)','Fraction of farmed from total salmon use (S)','Omega3 content in salmon (S)','Consider pollutant or net health effect? (P)','Dieldrin concentration in farmed salmon (S)','Toxaphene concentration in farmed salmon (S)','PCB concentration in farmed salmon (S)','Farmed salmon use after recommendation (S)','Lower limits for pollutants in fish feed? (P)','Recommend restricted farmed salmon consumption? (P)','Total VOI','Pollutant levels in fish feed after lower limits (S+P)','Salmon consumption after feed limits (S+P)','Does omega-3 help CHD patients or everyone? (S)','Dose-response of health benefit (S)','Highest omega-3 dose with health benefit (S)','Current average consumption of salmon (S)','Fraction of farmed from total salmon use (S)','Omega3 content in salmon (S)','Consider pollutant or net health effect? (P)','Dieldrin concentration in farmed salmon (S)','Toxaphene concentration in farmed salmon (S)','PCB concentration in farmed salmon (S)','Farmed salmon use after recommendation (S)','Lower limits for pollutants in fish feed? (P)','Recommend restricted farmed salmon consumption? (P)'] 536,216,1 48,12 ['Total VOI','Pollutant levels in fish feed after lower limits (S+P)','Salmon consumption after feed limits (S+P)','Does omega-3 help CHD patients or everyone? (S)','Dose-response of health benefit (S)','Highest omega-3 dose with health benefit (S)','Current average consumption of salmon (S)','Fraction of farmed from total salmon use (S)','Omega3 content in salmon (S)','Consider pollutant or net health effect? (P)','Dieldrin concentration in farmed salmon (S)','Toxaphene concentration in farmed salmon (S)','PCB concentration in farmed salmon (S)','Farmed salmon use after recommendation (S)','Lower limits for pollutants in fish feed? (P)','Recommend restricted farmed salmon consumption? (P)','Total VOI','Pollutant levels in fish feed after lower limits (S+P)','Salmon consumption after feed limits (S+P)','Does omega-3 help CHD patients or everyone? (S)','Dose-response of health benefit (S)','Highest omega-3 dose with health benefit (S)','Current average consumption of salmon (S)','Fraction of farmed from total salmon use (S)','Omega3 content in salmon (S)','Consider pollutant or net health effect? (P)','Dieldrin concentration in farmed salmon (S)','Toxaphene concentration in farmed salmon (S)','PCB concentration in farmed salmon (S)','Farmed salmon use after recommendation (S)','Lower limits for pollutants in fish feed? (P)','Recommend restricted farmed salmon consumption? (P)'] 28.1.2004 Jouni Tuomisto Tulos on laskettu 28.1.2004 malliversiolla TuomistoViljelylohi2004_4.ana (28.1.2004 14:42). Iteraatioita on ollut 2000 kussakin ajossa, ja siemenlukua on vaihdettu 13, 14...22. Table(Dee,Self)( 45.99,54.68,52.26,36.1612390137561,54.3154602065333,34.9994540997468,48.2712149729705,43.4418171126272,36.5685772254328,48.5061584782452, -7.28p,3.64p,29.1p,-40.0177668780088p,-18.1898940354586p,-10.9139364212751p,-3.63797880709171p,32.7418092638254p,-25.465851649642p,7.27595761418343p, -10.9p,3.64p,29.1p,-43.6557456851006p,-18.1898940354586p,-7.27595761418343p,-3.63797880709171p,32.7418092638254p,-25.465851649642p,7.27595761418343p, 0,-10.9p,40p,-25.465851649642p,-3.63797880709171p,-3.63797880709171p,-18.1898940354586p,10.9139364212751p,-40.0177668780088p,3.63797880709171p, -10.9p,0,21.8p,-40.0177668780088p,-14.5519152283669p,-7.27595761418343p,-3.63797880709171p,32.7418092638254p,-29.1038304567337p,3.63797880709171p, -3.64p,7.28p,25.5p,-43.6557456851006p,-10.9139364212751p,-7.27595761418343p,-7.27595761418343p,29.1038304567337p,-32.7418092638254p,3.63797880709171p, -7.28p,3.64p,25.5p,-43.6557456851006p,-14.5519152283669p,-7.27595761418343p,-7.27595761418343p,32.7418092638254p,-21.8278728425503p,3.63797880709171p, -7.28p,3.64p,29.1p,-43.6557456851006p,-14.5519152283669p,-7.27595761418343p,-3.63797880709171p,29.1038304567337p,-25.465851649642p,7.27595761418343p, -7.28p,3.64p,25.5p,-40.0177668780088p,-14.5519152283669p,-7.27595761418343p,-7.27595761418343p,29.1038304567337p,-25.465851649642p,3.63797880709171p, 19.73,19.19,19.44,19.4379094993274,20.0175573351808,20.3445513117949,20.355546642757,19.7440144359389,20.7034870828174,19.9763413781584, -7.28p,3.64p,29.1p,-43.6557456851006p,-10.9139364212751p,-7.27595761418343p,-3.63797880709171p,32.7418092638254p,-25.465851649642p,7.27595761418343p, -7.28p,0,29.1p,-43.6557456851006p,-14.5519152283669p,-7.27595761418343p,-7.27595761418343p,29.1038304567337p,-29.1038304567337p,3.63797880709171p, -7.28p,3.64p,29.1p,-40.0177668780088p,-18.1898940354586p,-7.27595761418343p,-3.63797880709171p,32.7418092638254p,-25.465851649642p,3.63797880709171p, -7.28p,0,29.1p,-43.6557456851006p,-14.5519152283669p,-10.9139364212751p,-3.63797880709171p,29.1038304567337p,-29.1038304567337p,7.27595761418343p, 14.6p,7.28p,29.1p,-36.3797880709171p,-14.5519152283669p,-18.1898940354586p,-7.27595761418343p,43.6557456851006p,-40.0177668780088p,7.27595761418343p, 3.64p,-3.64p,32.7p,-29.1038304567337p,-29.1038304567337p,-29.1038304567337p,-10.9139364212751p,43.6557456851006p,-32.7418092638254p,0, 320.6,318.5,264.9,335.708549076064,337.442817728655,275.665732995609,290.791226693727,334.370728607537,273.164494316921,276.459606918472, 10.57,14.86,41.8p,5.74955088028401,24.7671730730817,5.45696821063757p,-14.5519152283669p,4.67620054120562,-40.0177668780088p,-1.81898940354586p, 123.2,86.48,60.06,90.5814652189947,101.172076686928,59.0112207949551,50.290428820892,122.376689417411,54.4520162740264,81.5371850319334, -18.2p,18.2p,34.6p,9.09494701772928p,-3.63797880709171p,20.0088834390044p,-9.09494701772928p,18.1898940354586p,-36.3797880709171p,-16.3709046319127p, 2.138,1.82p,38.2p,-5.45696821063757p,11.8073357625708,7.27595761418343p,-12.732925824821p,9.96986357776404,-43.6557456851006p,1.81898940354586p, 6.398,3.079,43.7p,-9.09494701772928p,21.7569893201817,3.63797880709171p,-14.5519152283669p,18.4151329940305,-41.8367562815547p,-1.81898940354586p, 11.02,3.64p,41.8p,11.9510390913656,19.2005104308973,3.63797880709171p,-12.732925824821p,13.7459735344328,-40.0177668780088p,1.81898940354586p, 13.24,3.928,41.8p,-10.9139364212751p,6.94312189276934,3.84243531387074,-12.732925824821p,3.79393370039361,-41.8367562815547p,-1.81898940354586p, -20p,3.64p,13.18,2.94388484912088,6.21058777152939,5.45696821063757p,-12.732925824821p,3.40300298175498,-43.6557456851006p,6.49686528052371, -18.2p,3.64p,30.9p,-16.3709046319127p,10.9139364212751p,5.45696821063757p,-5.45696821063757p,9.09494701772928p,-12.732925824821p,1.81898940354586p, -20p,9.1p,41.8p,9.43435100685565,1.66582958040635,7.27595761418343p,-12.732925824821p,29.1038304567337p,-41.8367562815547p,-1.81898940354586p, 10.8,7.28p,41.8p,6.27069051176841,5.9436259337399,2.82376602475961,-14.5519152283669p,21.799220341687,-43.6557456851006p,-1.81898940354586p, 32.63,1.013,43.7p,-9.09494701772928p,14.1657807083811,0.412992603269231,-16.3709046319127p,29.1038304567337p,-41.8367562815547p,-1.81898940354586p, 7.526,5.46p,41.8p,16.9614523061118,33.5381902710542,7.27595761418343p,-12.732925824821p,29.0075866389925,-41.8367562815547p,1.81898940354586p, -10.9p,3.64p,34.6p,9.09494701772928p,-12.732925824821p,12.732925824821p,-20.0088834390044p,36.3797880709171p,-43.6557456851006p,-9.09494701772928p, -10.9p,9.1p,34.6p,5.45696821063757p,-9.09494701772928p,10.9139364212751p,-20.0088834390044p,32.7418092638254p,-40.0177668780088p,-10.9139364212751p ) ['Seed 13','Seed 14','Seed 15','Seed 16','Seed 17','Seed 18','Seed 19','Seed 20','Seed 21','Seed 22'] 536,184,1 48,24 2,130,115,985,303,0,MIDM 2,136,146,921,371,0,MIDM 65535,52427,65534 Graphtool:0 Distresol:10 Diststeps:1 Cdfresol:5 Cdfsteps:1 Symbolsize:6 Baroverlap:0 Linestyle:1 Frame:1 Grid:1 Ticks:1 Mesh:1 Scales:1 Rotation:45 Tilt:0 Depth:70 Frameauto:1 Showkey:1 Xminimum:0 Xmaximum:1 Yminimum:0 Ymaximum:1 Zminimum:0 Zmaximum:1 Xintervals:0 Yintervals:0 Includexzero:0 Includeyzero:0 Includezzero:0 Statsselect:[1,1,1,1,1,0,0,0] Probindex:[0.05,0.25,0.5,0.75,0.95] [Self,Dee] [Self,Dee] 28.1.2004 Jouni Tuomisto The result has been calculated with the model version TuomistoViljelylohi2004_4.ana (28.1.2004 14:42). We used 2000 iterations in each ten runs, and the random seed number was 13, 14...22. average(voi_result,voi_result) 640,184,1 48,24 2,120,59,1054,669,0,MIDM {!40000|Att_catlinestyle Graph_primary_valdim:9} {!40000|Flip:0} {!40000|Att_graphindexrange Dee:1,,,,,,10} {!40000|Att_graphvaluerange Combined_voi_result:1,,,,,,10}