Difference between revisions of "ERF of PFAS"

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PFAS|Increased ALT|Ingestion|ng /kg /wk|ERS|BW|0|0|EFSA?
 
PFAS|Increased ALT|Ingestion|ng /kg /wk|ERS|BW|0|0|EFSA?
 
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Immunosuppression is not well quantified. Here we assume that at the tolerable weekly intate (TWI) level, 10 % of respiratory infections are attributable to PFAS. The TWI comes from EFSA<ref>EFSA. (2020) Risk to human health related to the presence of perfluoroalkyl substances in food. https://doi.org/10.2903/j.efsa.2020.6223</ref>.
  
 
=== Calculations ===
 
=== Calculations ===

Revision as of 03:00, 26 February 2021


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The quality was last checked: 2021-01-29.


Question

What are the exposure-response functions (ERF) of perfluorinated alkyl substances (PFAS) on several health endpoints?

Answer

Rationale

Data

Difference between revisions of "ERF of PFAS"(-)
ObsExposure agentResponseExposureExposure unitER functionScalingThresholdERFDescription
1PFASPFAS TWIMaternal exposure via ingestionng /kg /wkTWIBW04.4EFSA 2020
2PFASImmunosuppressionMaternal ingested intakeng /kg /wkERSBW00.0227Converted from the row above assuming linearity and steady state
3PFASCholesterol increaseIngestionng /kg /wkERSBW00EFSA?
4PFASDecreased birth weightIngestionng /kg /wkERSBW00EFSA?
5PFASIncreased ALTIngestionng /kg /wkERSBW00EFSA?

Immunosuppression is not well quantified. Here we assume that at the tolerable weekly intate (TWI) level, 10 % of respiratory infections are attributable to PFAS. The TWI comes from EFSA[1].

Calculations

Initiation 2021-01-29

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See also

References

  1. EFSA. (2020) Risk to human health related to the presence of perfluoroalkyl substances in food. https://doi.org/10.2903/j.efsa.2020.6223